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RGS21-201 ,RGS21 ,Q2M5E4
  • Uniprot Accession= Q2M5E4
  • Ensembl Transcript= ENST00000417209.2
  • Uniprot Name= RGS21
  • Name= Regulator of G-protein signaling 21
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 8
GO term GO name GO namespace GO def
GO:0003924 GTPase activity molecular_function Catalysis of the reaction
GO:0007186 G protein-coupled receptor signaling pathway biological_process The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
GO:0009968 negative regulation of signal transduction biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. [GOC:sm]
GO:0019226 transmission of nerve impulse biological_process The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. [GOC:curators, ISBN:0815316194]
GO:0050913 sensory perception of bitter taste biological_process The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. [GOC:ai]
GO:0050916 sensory perception of sweet taste biological_process The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. [GOC:ai]
GO:0050917 sensory perception of umami taste biological_process The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process. [GOC:ai]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]