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RGS4-203 ,RGS4 ,P49798
  • Uniprot Accession= P49798
  • Ensembl Transcript= ENST00000367909.11
  • Uniprot Name= RGS4
  • Name= Regulator of G-protein signaling 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 24
GO term GO name GO namespace GO def
GO:0001965 G-protein alpha-subunit binding molecular_function Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide. [GOC:hjd]
GO:0003924 GTPase activity molecular_function Catalysis of the reaction
GO:0005096 GTPase activator activity molecular_function Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. [GOC:mah]
GO:0005516 calmodulin binding molecular_function Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. [GOC:krc]
GO:0019901 protein kinase binding molecular_function Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. [GOC:jl]
GO:0001975 response to amphetamine biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine. [GOC:dph, GOC:ef]
GO:0007186 G protein-coupled receptor signaling pathway biological_process The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
GO:0008277 regulation of G protein-coupled receptor signaling pathway biological_process Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators]
GO:0010460 positive regulation of heart rate biological_process Any process that activates or increases the frequency or rate of heart contraction. [GOC:dph, GOC:tb]
GO:0042220 response to cocaine biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. [GOC:ef, GOC:jl]
GO:0045471 response to ethanol biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. [GOC:go_curators]
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators]
GO:0051924 regulation of calcium ion transport biological_process Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0060160 negative regulation of dopamine receptor signaling pathway biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. [GOC:dph]
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development biological_process Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. [GOC:dph]
GO:0110053 regulation of actin filament organization biological_process Any process that modulates the frequency, rate or extent of actin filament organization. [GOC:kmv]
GO:1900924 negative regulation of glycine import across plasma membrane biological_process Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell. [GOC:TermGenie]
GO:1901380 negative regulation of potassium ion transmembrane transport biological_process Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport. [GOC:BHF, GOC:TermGenie]
GO:1990791 dorsal root ganglion development biological_process The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure. [PMID:18583150]
GO:2000463 positive regulation of excitatory postsynaptic potential biological_process Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. [GOC:bf, GOC:BHF]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0032991 protein-containing complex cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah]