GO term | GO name | GO namespace | GO def |
GO:0001965 | G-protein alpha-subunit binding | molecular_function | Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide. [GOC:hjd] |
GO:0003924 | GTPase activity | molecular_function | Catalysis of the reaction |
GO:0005096 | GTPase activator activity | molecular_function | Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. [GOC:mah] |
GO:0031681 | G-protein beta-subunit binding | molecular_function | Binding to a G-protein beta subunit. [GOC:mah] |
GO:0001975 | response to amphetamine | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine. [GOC:dph, GOC:ef] |
GO:0007186 | G protein-coupled receptor signaling pathway | biological_process | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor] |
GO:0035556 | intracellular signal transduction | biological_process | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] |
GO:0043547 | positive regulation of GTPase activity | biological_process | Any process that activates or increases the activity of a GTPase. [GOC:jl, GOC:mah] |
GO:0045471 | response to ethanol | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. [GOC:go_curators] |
GO:0045744 | negative regulation of G protein-coupled receptor signaling pathway | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators] |
GO:1901381 | positive regulation of potassium ion transmembrane transport | biological_process | Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. [GOC:BHF, GOC:TermGenie] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0005635 | nuclear envelope | cellular_component | The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). [ISBN:0198547684] |
GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
GO:0032991 | protein-containing complex | cellular_component | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah] |
GO:0008277 | regulation of G protein-coupled receptor signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators] |
GO:0043005 | neuron projection | cellular_component | A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:jl, http://www.cogsci.princeton.edu/~wn/] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |