Filter in search result
Please select a valid state.
RHOU-201 ,RHOU ,Q7L0Q8
  • Uniprot Accession= Q7L0Q8
  • Ensembl Transcript= ENST00000366691.4
  • Uniprot Name= RHOU
  • Name= Rho-related GTP-binding protein RhoU
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 23
GO term GO name GO namespace GO def
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0046872 metal ion binding molecular_function Binding to a metal ion. [GOC:ai]
GO:0000082 G1/S transition of mitotic cell cycle biological_process The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. [GOC:mtg_cell_cycle]
GO:0007010 cytoskeleton organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. [GOC:dph, GOC:jl, GOC:mah]
GO:0008360 regulation of cell shape biological_process Any process that modulates the surface configuration of a cell. [GOC:dph, GOC:go_curators, GOC:tb]
GO:0016601 Rac protein signal transduction biological_process An intracellular signaling cassette in which a small monomeric GTPase of the Rac subfamily relays a signal. [GOC:bf]
GO:0051056 regulation of small GTPase mediated signal transduction biological_process Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. [GOC:go_curators]
GO:1903955 positive regulation of protein targeting to mitochondrion biological_process Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24270810]
GO:0000139 Golgi membrane cellular_component The lipid bilayer surrounding any of the compartments of the Golgi apparatus. [GOC:mah]
GO:0002102 podosome cellular_component An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. [PMID:12837608, PMID:15890982]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0005925 focal adhesion cellular_component A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). [GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002]
GO:0010008 endosome membrane cellular_component The lipid bilayer surrounding an endosome. [GOC:mah]
GO:0042995 cell projection cellular_component A prolongation or process extending from a cell, e.g. a flagellum or axon. [GOC:jl, http://www.cogsci.princeton.edu/~wn/]
GO:0005525 GTP binding molecular_function Binding to GTP, guanosine triphosphate. [GOC:ai]
GO:0003924 GTPase activity molecular_function Catalysis of the reaction
GO:0006897 endocytosis biological_process A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis]
GO:0007015 actin filament organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. [GOC:mah]
GO:0007163 establishment or maintenance of cell polarity biological_process Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. [GOC:mah]
GO:0032488 Cdc42 protein signal transduction biological_process An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal. [GOC:mah, PMID:18558478]
GO:0019901 protein kinase binding molecular_function Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. [GOC:jl]