| GO term | GO name | GO namespace | GO def |
| GO:0000287 | magnesium ion binding | molecular_function | Binding to a magnesium (Mg) ion. [GOC:ai] |
| GO:0003924 | GTPase activity | molecular_function | Catalysis of the reaction |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005525 | GTP binding | molecular_function | Binding to GTP, guanosine triphosphate. [GOC:ai] |
| GO:0019003 | GDP binding | molecular_function | Binding to GDP, guanosine 5'-diphosphate. [GOC:ai] |
| GO:0043495 | protein-membrane adaptor activity | molecular_function | The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. [GOC:go_curators] |
| GO:0046982 | protein heterodimerization activity | molecular_function | Binding to a nonidentical protein to form a heterodimer. [GOC:ai] |
| GO:0051020 | GTPase binding | molecular_function | Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP. [GOC:ai] |
| GO:0060090 | molecular adaptor activity | molecular_function | The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. [GOC:mtg_MIT_16mar07, GOC:vw] |
| GO:0140767 | enzyme-substrate adaptor activity | molecular_function | An adaptor that brings together an enzyme and its substrate. Adaptors recruit the substrate to its enzyme, thus contributing to substrate selection and specificity. [PMID:16250895, PMID:34358446] |
| GO:0006351 | DNA-templated transcription | biological_process | The synthesis of an RNA transcript from a DNA template. [GOC:jl, GOC:txnOH] |
| GO:0006915 | apoptotic process | biological_process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] |
| GO:0007264 | small GTPase-mediated signal transduction | biological_process | An intracellular signaling cassette in which a small monomeric GTPase relays a signal. [GOC:mah] |
| GO:0008104 | protein localization | biological_process | Any process in which a protein is transported to, or maintained in, a specific location. [GOC:ai] |
| GO:0008380 | RNA splicing | biological_process | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:krc, GOC:mah] |
| GO:0031669 | cellular response to nutrient levels | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. [GOC:mah] |
| GO:0032006 | regulation of TOR signaling | biological_process | Any process that modulates the frequency, rate or extent of TOR signaling. [GOC:mah] |
| GO:0034198 | cellular response to amino acid starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. [GOC:ecd] |
| GO:0043200 | response to amino acid | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. [GOC:ef, GOC:mlg] |
| GO:0061462 | protein localization to lysosome | biological_process | A process in which a protein is transported to, or maintained in, a location within a lysosome. [GOC:dph] |
| GO:0071230 | cellular response to amino acid stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. [GOC:mah] |
| GO:0072657 | protein localization to membrane | biological_process | A process in which a protein is transported to, or maintained in, a specific location in a membrane. [GOC:mah] |
| GO:1903432 | regulation of TORC1 signaling | biological_process | Any process that modulates the frequency, rate or extent of TORC1 signaling. [GO_REF:0000058, GOC:TermGenie] |
| GO:1904263 | positive regulation of TORC1 signaling | biological_process | Any process that activates or increases the frequency, rate or extent of TORC1 signaling. [GO_REF:0000058, GOC:TermGenie, PMID:25366275] |
| GO:0005765 | lysosomal membrane | cellular_component | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005764 | lysosome | cellular_component | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. [GOC:mah, ISBN:0198506732] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0043231 | intracellular membrane-bounded organelle | cellular_component | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators] |
| GO:1990877 | FNIP-folliculin RagC/D GAP | cellular_component | A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2. [GOC:rn, PMID:24095279, PMID:26387955, PMID:34805795] |
| GO:0010507 | negative regulation of autophagy | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. [GOC:dph, GOC:tb] |
| GO:0009267 | cellular response to starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. [GOC:jl] |
| GO:1990131 | Gtr1-Gtr2 GTPase complex | cellular_component | A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins. [GOC:rb, PMID:10388807, PMID:16143306] |