| GO term | GO name | GO namespace | GO def |
| GO:0005507 | copper ion binding | molecular_function | Binding to a copper (Cu) ion. [GOC:ai] |
| GO:0005509 | calcium ion binding | molecular_function | Binding to a calcium ion (Ca2+). [GOC:ai] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0008270 | zinc ion binding | molecular_function | Binding to a zinc ion (Zn). [GOC:ai] |
| GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
| GO:0050786 | RAGE receptor binding | molecular_function | Binding to a RAGE receptor, the receptor for advanced glycation end-products. [GOC:ai] |
| GO:0002548 | monocyte chemotaxis | biological_process | The movement of a monocyte in response to an external stimulus. [GOC:add, PMID:11696603, PMID:15173832] |
| GO:0006805 | xenobiotic metabolic process | biological_process | The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc] |
| GO:0006954 | inflammatory response | biological_process | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732] |
| GO:0030593 | neutrophil chemotaxis | biological_process | The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. [GOC:jl, ISBN:0198506732] |
| GO:0031640 | killing of cells of another organism | biological_process | Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. [GOC:add] |
| GO:0042742 | defense response to bacterium | biological_process | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. [GOC:jl] |
| GO:0043123 | positive regulation of canonical NF-kappaB signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade. [GOC:jl] |
| GO:0043406 | positive regulation of MAP kinase activity | biological_process | Any process that activates or increases the frequency, rate or extent of MAP kinase activity. [GOC:dph, GOC:go_curators] |
| GO:0045087 | innate immune response | biological_process | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] |
| GO:0045576 | mast cell activation | biological_process | The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. [GOC:mgi_curators, ISBN:0781735149] |
| GO:0050729 | positive regulation of inflammatory response | biological_process | Any process that activates or increases the frequency, rate or extent of the inflammatory response. [GOC:ai] |
| GO:0050832 | defense response to fungus | biological_process | Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. [GOC:ai] |
| GO:0051092 | positive regulation of NF-kappaB transcription factor activity | biological_process | Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030] |
| GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide | biological_process | An immune response against microbes mediated by anti-microbial peptides in body fluid. [PMID:15761415, PMID:24287494] |
| GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0005856 | cytoskeleton | cellular_component | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. [GOC:mah, PMID:16959967, PMID:27419875] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0034774 | secretory granule lumen | cellular_component | The volume enclosed by the membrane of a secretory granule. [GOC:rph] |
| GO:0048306 | calcium-dependent protein binding | molecular_function | Binding to a protein or protein complex in the presence of calcium. [GOC:jid, PMID:10485905] |
| GO:0043542 | endothelial cell migration | biological_process | The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. [GOC:go_curators] |