| GO term | GO name | GO namespace | GO def |
| GO:0032542 | sulfiredoxin activity | molecular_function | Catalysis of the reaction |
| GO:0044877 | protein-containing complex binding | molecular_function | Binding to a macromolecular complex. [GOC:jl] |
| GO:0098869 | cellular oxidant detoxification | biological_process | Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. [GOC:dos, GOC:vw] |
| GO:0031588 | nucleotide-activated protein kinase complex | cellular_component | A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae). [GOC:bhm, GOC:mah, GOC:vw] |
| GO:0031932 | TORC2 complex | cellular_component | A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. [GOC:bf, GOC:jh, PMID:14736892, PMID:15780592, PMID:16469695, PMID:21548787] |
| GO:0004601 | peroxidase activity | molecular_function | Catalysis of the reaction |
| GO:0005092 | GDP-dissociation inhibitor activity | molecular_function | Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding. [GOC:mah] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0042731 | PH domain binding | molecular_function | Binding to a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton. [GOC:jl, Pfam:PF00169] |
| GO:0070728 | leucine binding | molecular_function | Binding to 2-amino-4-methylpentanoic acid. [GOC:BHF, GOC:mah] |
| GO:0140311 | protein sequestering activity | molecular_function | Binding to a protein to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active. [PMID:1493333] |
| GO:0001932 | regulation of protein phosphorylation | biological_process | Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. [GOC:hjd] |
| GO:0006111 | regulation of gluconeogenesis | biological_process | Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. [GOC:go_curators] |
| GO:0006635 | fatty acid beta-oxidation | biological_process | A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). [GOC:mah, ISBN:0198506732, MetaCyc:FAO-PWY] |
| GO:0009749 | response to glucose | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. [GOC:jl] |
| GO:0016239 | positive regulation of macroautophagy | biological_process | Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. [GOC:go_curators, PMID:9412464] |
| GO:0030308 | negative regulation of cell growth | biological_process | Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:0030330 | DNA damage response, signal transduction by p53 class mediator | biological_process | A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. [GOC:go_curators] |
| GO:0032042 | mitochondrial DNA metabolic process | biological_process | The chemical reactions and pathways involving mitochondrial DNA. [GOC:mah] |
| GO:0032868 | response to insulin | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732] |
| GO:0034198 | cellular response to amino acid starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. [GOC:ecd] |
| GO:0034599 | cellular response to oxidative stress | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. [GOC:mah] |
| GO:0042149 | cellular response to glucose starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose. [GOC:jl] |
| GO:0042593 | glucose homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. [GOC:go_curators] |
| GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological_process | An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway. [PMID:20517722, PMID:22952397] |
| GO:0046323 | glucose import | biological_process | The directed movement of the hexose monosaccharide glucose into a cell or organelle. [GOC:ai] |
| GO:0070328 | triglyceride homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell. [GOC:BHF, GOC:mah] |
| GO:0071230 | cellular response to amino acid stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. [GOC:mah] |
| GO:0071233 | cellular response to leucine | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus. [GOC:mah] |
| GO:0072593 | reactive oxygen species metabolic process | biological_process | The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. [GOC:mah] |
| GO:1900182 | positive regulation of protein localization to nucleus | biological_process | Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. [GOC:TermGenie] |
| GO:1901031 | regulation of response to reactive oxygen species | biological_process | Any process that modulates the frequency, rate or extent of response to reactive oxygen species. [GOC:kmv, GOC:TermGenie] |
| GO:1902010 | negative regulation of translation in response to endoplasmic reticulum stress | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. [GOC:dph, GOC:TermGenie, PMID:10882126] |
| GO:1903432 | regulation of TORC1 signaling | biological_process | Any process that modulates the frequency, rate or extent of TORC1 signaling. [GO_REF:0000058, GOC:TermGenie] |
| GO:1904262 | negative regulation of TORC1 signaling | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling. [GO_REF:0000058, GOC:TermGenie, PMID:25366275] |
| GO:1904263 | positive regulation of TORC1 signaling | biological_process | Any process that activates or increases the frequency, rate or extent of TORC1 signaling. [GO_REF:0000058, GOC:TermGenie, PMID:25366275] |
| GO:1904504 | positive regulation of lipophagy | biological_process | Any process that activates or increases the frequency, rate or extent of lipophagy. [GO_REF:0000058, GOC:autophagy, GOC:dph, GOC:TermGenie, PMID:25383539] |
| GO:1990253 | cellular response to leucine starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine. [PMID:19033384] |
| GO:0005765 | lysosomal membrane | cellular_component | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005739 | mitochondrion | cellular_component | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:1990316 | Atg1/ULK1 kinase complex | cellular_component | A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation. [GOC:bhm, GOC:DOS, GOC:rb, PMID:15743910, PMID:19211835, PMID:19258318, PMID:19597335, PMID:22885598] |
| GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor | molecular_function | Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor. [GOC:ai] |