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SH3BP5L-201 ,SH3BP5L ,Q7L8J4
  • Uniprot Accession= Q7L8J4
  • Ensembl Transcript= ENST00000366472.6
  • Uniprot Name= SH3BP5L
  • Name= SH3 domain-binding protein 5-like
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 5
GO term GO name GO namespace GO def
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0035556 intracellular signal transduction biological_process The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0004860 protein kinase inhibitor activity molecular_function Binds to and stops, prevents or reduces the activity of a protein kinase. [GOC:ai]