| GO term | GO name | GO namespace | GO def |
| GO:0001784 | phosphotyrosine residue binding | molecular_function | Binding to a phosphorylated tyrosine residue within a protein. [PMID:14636584] |
| GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity | molecular_function | The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way. [GOC:mtg_MIT_16mar07, PMID:10502414, PMID:20565848] |
| GO:0005154 | epidermal growth factor receptor binding | molecular_function | Binding to an epidermal growth factor receptor. [GOC:ai] |
| GO:0005158 | insulin receptor binding | molecular_function | Binding to an insulin receptor. [GOC:ai] |
| GO:0005159 | insulin-like growth factor receptor binding | molecular_function | Binding to an insulin-like growth factor receptor. [GOC:jl] |
| GO:0005168 | neurotrophin TRKA receptor binding | molecular_function | Binding to a neurotrophin TRKA receptor. [GOC:ai] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005543 | phospholipid binding | molecular_function | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. [ISBN:0198506732] |
| GO:0046875 | ephrin receptor binding | molecular_function | Binding to an ephrin receptor. [GOC:ai] |
| GO:0048408 | epidermal growth factor binding | molecular_function | Binding to epidermal growth factor. [GOC:dgh] |
| GO:0001525 | angiogenesis | biological_process | Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. [ISBN:0878932453] |
| GO:0007507 | heart development | biological_process | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:jid, UBERON:0000948] |
| GO:0008284 | positive regulation of cell population proliferation | biological_process | Any process that activates or increases the rate or extent of cell proliferation. [GOC:go_curators] |
| GO:0008286 | insulin receptor signaling pathway | biological_process | The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. [GOC:ceb] |
| GO:0030036 | actin cytoskeleton organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. [GOC:dph, GOC:jl, GOC:mah] |
| GO:0035556 | intracellular signal transduction | biological_process | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] |
| GO:0042742 | defense response to bacterium | biological_process | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. [GOC:jl] |
| GO:0043066 | negative regulation of apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| GO:0043410 | positive regulation of MAPK cascade | biological_process | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. [GOC:go_curators] |
| GO:0045892 | negative regulation of DNA-templated transcription | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH] |
| GO:0045893 | positive regulation of DNA-templated transcription | biological_process | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH] |
| GO:0048009 | insulin-like growth factor receptor signaling pathway | biological_process | The series of molecular signals initiated by a ligand binding to an insulin-like growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb] |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | biological_process | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. [GOC:mah] |
| GO:0071363 | cellular response to growth factor stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. [GOC:mah] |
| GO:0098609 | cell-cell adhesion | biological_process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |
| GO:0005759 | mitochondrial matrix | cellular_component | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. [GOC:as, ISBN:0198506732] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0005925 | focal adhesion | cellular_component | A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). [GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002] |
| GO:0070435 | Shc-EGFR complex | cellular_component | A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway. [GOC:mah, PMID:7798267] |
| GO:0030971 | receptor tyrosine kinase binding | molecular_function | Binding to a receptor that possesses protein tyrosine kinase activity. [GOC:mah] |
| GO:0007173 | epidermal growth factor receptor signaling pathway | biological_process | The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. [GOC:ceb] |