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SLC1A7-202 ,SLC1A7 ,O00341
  • Uniprot Accession= O00341
  • Ensembl Transcript= ENST00000371494.9
  • Uniprot Name= SLC1A7
  • Name= Excitatory amino acid transporter 5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 16
GO term GO name GO namespace GO def
GO:0005313 L-glutamate transmembrane transporter activity molecular_function Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
GO:0005314 high-affinity L-glutamate transmembrane transporter activity molecular_function Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. [TC:2.A.3.10.5]
GO:0008068 extracellularly glutamate-gated chloride channel activity molecular_function Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. [GOC:mtg_transport, ISBN:0815340729]
GO:0015501 glutamate:sodium symporter activity molecular_function Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction
GO:0001504 neurotransmitter uptake biological_process The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. [ISBN:0123668387]
GO:0006811 monoatomic ion transport biological_process The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. [GOC:ai]
GO:0006835 dicarboxylic acid transport biological_process The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]
GO:0006836 neurotransmitter transport biological_process The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. [GOC:ai]
GO:0015804 neutral amino acid transport biological_process The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0015813 L-glutamate transmembrane transport biological_process The directed movement of L-glutamate across a membrane. [PMID:21307582]
GO:0060079 excitatory postsynaptic potential biological_process A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. [GOC:dph, GOC:ef]
GO:1902476 chloride transmembrane transport biological_process The process in which chloride is transported across a membrane. [GOC:TermGenie, GOC:vw]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0097060 synaptic membrane cellular_component A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. [GOC:BHF, PMID:20410104]
GO:0098794 postsynapse cellular_component The part of a synapse that is part of the post-synaptic cell. [GOC:dos]
GO:0015175 neutral L-amino acid transmembrane transporter activity molecular_function Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]