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SMG7-201 ,SMG7 ,Q92540
  • Uniprot Accession= Q92540
  • Ensembl Transcript= ENST00000347615.6
  • Uniprot Name= SMG7
  • Name= Nonsense-mediated mRNA decay factor SMG7
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 11
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0042162 telomeric DNA binding molecular_function Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. [GOC:jl, SO:0000624]
GO:0051721 protein phosphatase 2A binding molecular_function Binding to protein phosphatase 2A. [GOC:ai]
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biological_process The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. [GOC:krc, GOC:ma, PMID:10025395]
GO:0006406 mRNA export from nucleus biological_process The directed movement of mRNA from the nucleus to the cytoplasm. [GOC:ma]
GO:0035303 regulation of dephosphorylation biological_process Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0070034 telomerase RNA binding molecular_function Binding to the telomerase RNA template. [GOC:krc, PMID:16884717]
GO:0005697 telomerase holoenzyme complex cellular_component Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits. [PMID:11884619]