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SMYD3-214 ,SMYD3 ,Q9H7B4
  • Uniprot Accession= Q9H7B4
  • Ensembl Transcript= ENST00000490107.6
  • Uniprot Name= SMYD3
  • Name= Histone-lysine N-methyltransferase SMYD3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 18
GO term GO name GO namespace GO def
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. [GOC:txnOH-2018]
GO:0000993 RNA polymerase II complex binding molecular_function Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits. [GOC:txnOH]
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding molecular_function Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within. [GOC:txnOH]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0046872 metal ion binding molecular_function Binding to a metal ion. [GOC:ai]
GO:0140939 histone H4 methyltransferase activity molecular_function Catalysis of the reaction
GO:0140954 histone H3K36 dimethyltransferase activity molecular_function Catalysis of the reaction
GO:0140999 histone H3K4 trimethyltransferase activity molecular_function Catalysis of the reaction
GO:0006334 nucleosome assembly biological_process The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. [GOC:mah]
GO:0014904 myotube cell development biological_process The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:mtg_muscle]
GO:0032259 methylation biological_process The process in which a methyl group is covalently attached to a molecule. [GOC:mah]
GO:0033138 positive regulation of peptidyl-serine phosphorylation biological_process Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine. [GOC:mah]
GO:0045184 establishment of protein localization biological_process The directed movement of a protein to a specific location. [GOC:bf]
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH]
GO:0071549 cellular response to dexamethasone stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. [GOC:mah, GOC:yaf]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]