GO term | GO name | GO namespace | GO def |
GO:0005198 | structural molecule activity | molecular_function | The action of a molecule that contributes to the structural integrity of a complex. [GOC:mah, GOC:vw] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0030280 | structural constituent of skin epidermis | molecular_function | The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure. [GOC:mah] |
GO:0008544 | epidermis development | biological_process | The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. [GOC:go_curators, UBERON:0001003] |
GO:0018149 | peptide cross-linking | biological_process | The formation of a covalent cross-link between or within protein chains. [GOC:jsg] |
GO:0031424 | keratinization | biological_process | The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. [GOC:dph, GOC:ebc, GOC:sdb_2009, GOC:tb] |
GO:0001533 | cornified envelope | cellular_component | A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes). [GOC:add, PMID:11112355, PMID:11590230, PMID:15803139] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |