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SRSF4-201 ,SRSF4 ,Q08170
  • Uniprot Accession= Q08170
  • Ensembl Transcript= ENST00000373795.7
  • Uniprot Name= SRSF4
  • Name= Serine/arginine-rich splicing factor 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 12
GO term GO name GO namespace GO def
GO:0003723 RNA binding molecular_function Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:1990825 sequence-specific mRNA binding molecular_function Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif. [PMID:11886857]
GO:0000375 RNA splicing, via transesterification reactions biological_process Splicing of RNA via a series of two transesterification reactions. [GOC:krc]
GO:0006397 mRNA processing biological_process Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. [GOC:mah]
GO:0008380 RNA splicing biological_process The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:krc, GOC:mah]
GO:0032868 response to insulin biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732]
GO:0048025 negative regulation of mRNA splicing, via spliceosome biological_process Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. [GOC:jid]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0016607 nuclear speck cellular_component A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. [http://www.cellnucleus.com/]
GO:0000398 mRNA splicing, via spliceosome biological_process The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. [GOC:krc, ISBN:0198506732, ISBN:0879695897]