GO term | GO name | GO namespace | GO def |
GO:0003697 | single-stranded DNA binding | molecular_function | Binding to single-stranded DNA. [GOC:elh, GOC:vw, PMID:22976174] |
GO:0003713 | transcription coactivator activity | molecular_function | A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. [GOC:txnOH-2018, PMID:10213677, PMID:16858867] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0002244 | hematopoietic progenitor cell differentiation | biological_process | The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] |
GO:0008284 | positive regulation of cell population proliferation | biological_process | Any process that activates or increases the rate or extent of cell proliferation. [GOC:go_curators] |
GO:0021501 | prechordal plate formation | biological_process | The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] |
GO:0021547 | midbrain-hindbrain boundary initiation | biological_process | The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513] |
GO:0048382 | mesendoderm development | biological_process | The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues. [GOC:jid] |
GO:0060323 | head morphogenesis | biological_process | The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. [GOC:dph] |
GO:0065003 | protein-containing complex assembly | biological_process | The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. [GOC:jl] |
GO:2000744 | positive regulation of anterior head development | biological_process | Any process that activates or increases the frequency, rate or extent of anterior head development. [GOC:obol] |
GO:0005667 | transcription regulator complex | cellular_component | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. [GOC:jl] |
GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH] |