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STIL-202 ,STIL ,Q15468
  • Uniprot Accession= Q15468
  • Ensembl Transcript= ENST00000360380.7
  • Uniprot Name= STIL
  • Name= SCL-interrupting locus protein
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of GO Term: 29
GO term GO name GO namespace GO def
GO:0007052 mitotic spindle organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. [GOC:go_curators, GOC:mah]
GO:0051298 centrosome duplication biological_process The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. [GOC:ai]
GO:0071539 protein localization to centrosome biological_process A process in which a protein is transported to, or maintained at, the centrosome. [GOC:ecd]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0000578 embryonic axis specification biological_process The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb]
GO:0001701 in utero embryonic development biological_process The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. [GOC:go_curators, GOC:mtg_sensu]
GO:0001843 neural tube closure biological_process The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. [GOC:dph, ISBN:0878932437]
GO:0001947 heart looping biological_process The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation. [GOC:dph, PMID:12094232]
GO:0007224 smoothened signaling pathway biological_process The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. [GOC:mah, PMID:15057936, PMID:15205520]
GO:0007368 determination of left/right symmetry biological_process The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. [GOC:dph, GOC:jid]
GO:0021915 neural tube development biological_process The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
GO:0030900 forebrain development biological_process The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain]
GO:0030903 notochord development biological_process The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. [GOC:dgh]
GO:0033504 floor plate development biological_process The progression of the floor plate over time from its initial formation until its mature state. [GOC:dh]
GO:0035264 multicellular organism growth biological_process The increase in size or mass of an entire multicellular organism, as opposed to cell growth. [GOC:bf, GOC:curators, GOC:dph, GOC:tb]
GO:0043066 negative regulation of apoptotic process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0046599 regulation of centriole replication biological_process Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole. [GOC:ai]
GO:0046601 positive regulation of centriole replication biological_process Any process that activates or increases the frequency, rate or extent of centriole replication. [GOC:ai]
GO:0060236 regulation of mitotic spindle organization biological_process Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. [GOC:ascb_2009, GOC:dph, GOC:tb]
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle biological_process Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. [GOC:mtg_cell_cycle]
GO:1905832 positive regulation of spindle assembly biological_process Any process that activates or increases the frequency, rate or extent of spindle assembly. [GO_REF:0000058, GOC:TermGenie, PMID:27689799]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005813 centrosome cellular_component A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. [GOC:mah, ISBN:0198547684]
GO:0005814 centriole cellular_component A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0005938 cell cortex cellular_component The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. [GOC:mah, ISBN:0815316194]
GO:0120099 procentriole replication complex cellular_component A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates. [GOC:bhm, PMID:17576815, PMID:18207742, PMID:21059844, PMID:22020124, PMID:24997597]