| GO term | GO name | GO namespace | GO def |
| GO:0005509 | calcium ion binding | molecular_function | Binding to a calcium ion (Ca2+). [GOC:ai] |
| GO:0005544 | calcium-dependent phospholipid binding | molecular_function | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium. [GOC:jl] |
| GO:0008021 | synaptic vesicle | cellular_component | A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. [PMID:10099709, PMID:12563290] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0031369 | translation initiation factor binding | molecular_function | Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation. [GOC:mah] |
| GO:0031625 | ubiquitin protein ligase binding | molecular_function | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp] |
| GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
| GO:0048487 | beta-tubulin binding | molecular_function | Binding to the microtubule constituent protein beta-tubulin. [GOC:krc] |
| GO:0001778 | plasma membrane repair | biological_process | The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress. [GOC:add, PMID:12925704] |
| GO:0001818 | negative regulation of cytokine production | biological_process | Any process that stops, prevents, or reduces the rate of production of a cytokine. [GOC:add, ISBN:0781735149] |
| GO:0006914 | autophagy | biological_process | The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation. [GOC:autophagy, ISBN:0198547684, PMID:11099404, PMID:29455577, PMID:9412464] |
| GO:0007612 | learning | biological_process | Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. [ISBN:0582227089, ISBN:0721662544] |
| GO:0007613 | memory | biological_process | The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). [GOC:curators, ISBN:0582227089] |
| GO:0032715 | negative regulation of interleukin-6 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. [GOC:mah] |
| GO:0032720 | negative regulation of tumor necrosis factor production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. [GOC:mah, PMID:10891884, PMID:15560120] |
| GO:0033602 | negative regulation of dopamine secretion | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. [GOC:sl] |
| GO:0045806 | negative regulation of endocytosis | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis. [GOC:go_curators] |
| GO:0046929 | negative regulation of neurotransmitter secretion | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. [GOC:ai] |
| GO:0050765 | negative regulation of phagocytosis | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis. [GOC:ai] |
| GO:0051650 | establishment of vesicle localization | biological_process | The directed movement of a vesicle to a specific location. [GOC:ai] |
| GO:1900242 | regulation of synaptic vesicle endocytosis | biological_process | Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis. [GOC:BHF, GOC:TermGenie] |
| GO:1900424 | regulation of defense response to bacterium | biological_process | Any process that modulates the frequency, rate or extent of defense response to bacterium. [GOC:TermGenie, PMID:22346749] |
| GO:1903979 | negative regulation of microglial cell activation | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation. [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] |
| GO:1905162 | regulation of phagosome maturation | biological_process | Any process that modulates the frequency, rate or extent of phagosome maturation. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:16908865, PMID:23303671] |
| GO:1905171 | positive regulation of protein localization to phagocytic vesicle | biological_process | Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23303671] |
| GO:1990927 | calcium ion regulated lysosome exocytosis | biological_process | The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. [PMID:10725327, PMID:11511344] |
| GO:0001891 | phagocytic cup | cellular_component | An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome. [PMID:10358769] |
| GO:0005764 | lysosome | cellular_component | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. [GOC:mah, ISBN:0198506732] |
| GO:0005765 | lysosomal membrane | cellular_component | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai] |
| GO:0005802 | trans-Golgi network | cellular_component | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. [GOC:vw, ISBN:0815316194] |
| GO:0014069 | postsynaptic density | cellular_component | An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. [GOC:BHF, GOC:dos, GOC:ef, GOC:jid, GOC:pr, GOC:sjp, http://molneuro.kaist.ac.kr/psd, PMID:14532281, Wikipedia:Postsynaptic_density] |
| GO:0030424 | axon | cellular_component | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. [GOC:nln, ISBN:0198506732] |
| GO:0030425 | dendrite | cellular_component | A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. [GOC:aruk, GOC:bc, GOC:dos, GOC:mah, GOC:nln, ISBN:0198506732] |
| GO:0030665 | clathrin-coated vesicle membrane | cellular_component | The lipid bilayer surrounding a clathrin-coated vesicle. [GOC:mah] |
| GO:0031982 | vesicle | cellular_component | Any small, fluid-filled, spherical organelle enclosed by membrane. [GOC:mah, GOC:pz, GOC:vesicles] |
| GO:0032009 | early phagosome | cellular_component | A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis. [GOC:mah, PMID:12388753] |
| GO:0043005 | neuron projection | cellular_component | A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:jl, http://www.cogsci.princeton.edu/~wn/] |
| GO:0043197 | dendritic spine | cellular_component | A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. [GOC:nln] |
| GO:0043204 | perikaryon | cellular_component | The portion of the cell soma (neuronal cell body) that excludes the nucleus. [GOC:jl] |
| GO:0045335 | phagocytic vesicle | cellular_component | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. [GOC:go_curators, ISBN:0198506732] |
| GO:0048787 | presynaptic active zone membrane | cellular_component | The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters. [PMID:12812759, PMID:12923177, PMID:3152289] |
| GO:0055037 | recycling endosome | cellular_component | An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane. [GOC:dph, GOC:jid, GOC:kmv, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101, PMID:21556374, PMID:21562044] |
| GO:0055038 | recycling endosome membrane | cellular_component | The lipid bilayer surrounding a recycling endosome. [GOC:jid, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101] |
| GO:0060076 | excitatory synapse | cellular_component | A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell. [GOC:dph, GOC:ef] |
| GO:0060077 | inhibitory synapse | cellular_component | A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell. [GOC:dph, GOC:ef] |
| GO:0098691 | dopaminergic synapse | cellular_component | A synapse that uses dopamine as a neurotransmitter. [GOC:dos] |
| GO:0098793 | presynapse | cellular_component | The part of a synapse that is part of the presynaptic cell. [GOC:dos] |
| GO:0071277 | cellular response to calcium ion | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. [GOC:mah] |
| GO:0001786 | phosphatidylserine binding | molecular_function | Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine. [ISBN:0198506732, PMID:12000961] |
| GO:0070382 | exocytic vesicle | cellular_component | A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. [GOC:kad, GOC:mah] |
| GO:0000149 | SNARE binding | molecular_function | Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. [PMID:12642621] |
| GO:0014059 | regulation of dopamine secretion | biological_process | Any process that modulates the frequency, rate or extent of the regulated release of dopamine. [GOC:ef] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0045202 | synapse | cellular_component | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] |
| GO:0017158 | regulation of calcium ion-dependent exocytosis | biological_process | Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. [GOC:go_curators] |
| GO:0030276 | clathrin binding | molecular_function | Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles. [GOC:jl, GOC:mah, ISBN:0198506732] |
| GO:0006906 | vesicle fusion | biological_process | Fusion of the membrane of a transport vesicle with its target membrane. [GOC:jid] |
| GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter | biological_process | The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels. [GOC:curators] |