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THEM5-201 ,THEM5 ,Q8N1Q8
  • Uniprot Accession= Q8N1Q8
  • Ensembl Transcript= ENST00000368817.10
  • Uniprot Name= THEM5
  • Name= Acyl-coenzyme A thioesterase THEM5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 6
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0052816 long-chain fatty acyl-CoA hydrolase activity molecular_function Catalysis of the reaction
GO:0006631 fatty acid metabolic process biological_process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. [ISBN:0198547684]
GO:0035336 long-chain fatty-acyl-CoA metabolic process biological_process The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [ISBN:0198506732]
GO:0035965 cardiolipin acyl-chain remodeling biological_process Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids. [GOC:bf, GOC:rb, PMID:19244244]
GO:0005759 mitochondrial matrix cellular_component The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. [GOC:as, ISBN:0198506732]