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TMOD4-201 ,TMOD4 ,Q9NZQ9
  • Uniprot Accession= Q9NZQ9
  • Ensembl Transcript= ENST00000295314.9
  • Uniprot Name= TMOD4
  • Name= Tropomodulin-4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 10
GO term
GO name
GO namespace
GO def
GO:0003779 actin binding molecular_function Binding to monomeric or multimeric forms of actin, including actin filaments. [GOC:clt]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0051694 pointed-end actin filament capping biological_process The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. [ISBN:071673706X]
GO:0005865 striated muscle thin filament cellular_component Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils. [ISBN:0815316194]
GO:0030239 myofibril assembly biological_process Formation of myofibrils, the repeating units of striated muscle. [GOC:mah]
GO:0006936 muscle contraction biological_process A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. [GOC:ef, GOC:mtg_muscle, ISBN:0198506732]
GO:0007015 actin filament organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. [GOC:mah]
GO:0030016 myofibril cellular_component The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. [ISBN:0815316194]
GO:0005856 cytoskeleton cellular_component A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. [GOC:mah, PMID:16959967, PMID:27419875]
GO:0005523 tropomyosin binding molecular_function Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle. [GOC:curators, ISBN:0815316194]