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TNFRSF14-201 ,TNFRSF14 ,Q92956
  • Uniprot Accession= Q92956
  • Ensembl Transcript= ENST00000355716.5
  • Uniprot Name= TNFRSF14
  • Name= Tumor necrosis factor receptor superfamily member 14
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of GO Term: 21
GO term GO name GO namespace GO def
GO:0001618 virus receptor activity molecular_function Combining with a virus component and mediating entry of the virus into the cell. [GOC:bf, GOC:dph, PMID:7621403, UniProtKB-KW:KW-1183]
GO:0005031 tumor necrosis factor receptor activity molecular_function Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function. [GOC:jl, http://lookwayup.com/]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0019955 cytokine binding molecular_function Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. [GOC:ai, GOC:bf, ISBN:0198599471]
GO:0031625 ubiquitin protein ligase binding molecular_function Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp]
GO:0002250 adaptive immune response biological_process An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149]
GO:0006955 immune response biological_process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. [GO_REF:0000022, GOC:add]
GO:0007166 cell surface receptor signaling pathway biological_process The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:mah, GOC:pr, GOC:signaling]
GO:0031295 T cell costimulation biological_process The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. [ISBN:0781735149]
GO:0033209 tumor necrosis factor-mediated signaling pathway biological_process The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]
GO:0045087 innate immune response biological_process Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu]
GO:0046718 symbiont entry into host cell biological_process The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell. [GOC:jl]
GO:1905675 negative regulation of adaptive immune memory response biological_process Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response. [GO_REF:0000058, GOC:TermGenie, PMID:26831526]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0009897 external side of plasma membrane cellular_component The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb]
GO:0050830 defense response to Gram-positive bacterium biological_process Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. [GOC:ai]
GO:0046642 negative regulation of alpha-beta T cell proliferation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation. [GOC:ai]
GO:0002720 positive regulation of cytokine production involved in immune response biological_process Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. [GOC:add]
GO:0050829 defense response to Gram-negative bacterium biological_process Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism. [GOC:ai]
GO:2000406 positive regulation of T cell migration biological_process Any process that activates or increases the frequency, rate or extent of T cell migration. [GOC:mah]
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai]