| GO term | GO name | GO namespace | GO def |
| GO:0043495 | protein-membrane adaptor activity | molecular_function | The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. [GOC:go_curators] |
| GO:0006606 | protein import into nucleus | biological_process | The directed movement of a protein from the cytoplasm to the nucleus. [GOC:jl] |
| GO:0006611 | protein export from nucleus | biological_process | The directed movement of a protein from the nucleus into the cytoplasm. [GOC:jl] |
| GO:0006999 | nuclear pore organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore. [GOC:dph, GOC:jid, GOC:jl, GOC:mah] |
| GO:0010793 | regulation of mRNA export from nucleus | biological_process | Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm. [GOC:dph, GOC:tb] |
| GO:0031647 | regulation of protein stability | biological_process | Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation. [GOC:dph, GOC:mah, GOC:tb] |
| GO:0042306 | regulation of protein import into nucleus | biological_process | Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. [GOC:jl] |
| GO:0043578 | nuclear matrix organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane. [GOC:dph, GOC:jl, GOC:mah] |
| GO:0046825 | regulation of protein export from nucleus | biological_process | Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. [GOC:bf] |
| GO:0051292 | nuclear pore complex assembly | biological_process | The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex. [GOC:ai, GOC:mah] |
| GO:0000776 | kinetochore | cellular_component | A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. [GOC:elh] |
| GO:0003682 | chromatin binding | molecular_function | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. [GOC:jl, ISBN:0198506732, PMID:20404130] |
| GO:0003723 | RNA binding | molecular_function | Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah] |
| GO:0003729 | mRNA binding | molecular_function | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. [GOC:kmv, GOC:pr, SO:0000234] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0015631 | tubulin binding | molecular_function | Binding to monomeric or multimeric forms of tubulin, including microtubules. [GOC:clt] |
| GO:0017056 | structural constituent of nuclear pore | molecular_function | The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules. [GOC:mah, PMID:25802992] |
| GO:0031072 | heat shock protein binding | molecular_function | Binding to a heat shock protein, a protein synthesized or activated in response to heat shock. [GOC:mah, GOC:vw] |
| GO:0042803 | protein homodimerization activity | molecular_function | Binding to an identical protein to form a homodimer. [GOC:jl] |
| GO:0051019 | mitogen-activated protein kinase binding | molecular_function | Binding to a mitogen-activated protein kinase. [GOC:ai] |
| GO:0070840 | dynein complex binding | molecular_function | Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity. [GOC:bf, GOC:BHF, GOC:mah] |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH] |
| GO:0006404 | RNA import into nucleus | biological_process | The import of RNA from the cytoplasm to the nucleus. [GOC:ma] |
| GO:0006405 | RNA export from nucleus | biological_process | The directed movement of RNA from the nucleus to the cytoplasm. [GOC:ma] |
| GO:0006913 | nucleocytoplasmic transport | biological_process | The directed movement of molecules between the nucleus and the cytoplasm. [GOC:go_curators] |
| GO:0007094 | mitotic spindle assembly checkpoint signaling | biological_process | A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC). [GOC:mtg_cell_cycle, PMID:12360190] |
| GO:0010965 | regulation of mitotic sister chromatid separation | biological_process | Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. [GOC:dph, GOC:tb] |
| GO:0031453 | positive regulation of heterochromatin formation | biological_process | Any process that activates or increases the frequency, rate or extent of heterochromatin formation. [GOC:mah] |
| GO:0031990 | mRNA export from nucleus in response to heat stress | biological_process | The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export. [GOC:mah, GOC:vw] |
| GO:0032880 | regulation of protein localization | biological_process | Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. [GOC:dph, GOC:mah, GOC:tb] |
| GO:0034605 | cellular response to heat | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. [GOC:mah] |
| GO:0035457 | cellular response to interferon-alpha | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. [GOC:sl] |
| GO:0042307 | positive regulation of protein import into nucleus | biological_process | Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. [GOC:jl] |
| GO:0045947 | negative regulation of translational initiation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. [GOC:go_curators] |
| GO:0046827 | positive regulation of protein export from nucleus | biological_process | Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. [GOC:bf] |
| GO:0046832 | negative regulation of RNA export from nucleus | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm. [GOC:bf] |
| GO:0051301 | cell division | biological_process | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. [GOC:di, GOC:go_curators, GOC:pr] |
| GO:0070849 | response to epidermal growth factor | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. [GOC:BHF, GOC:mah] |
| GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint | biological_process | Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. [GOC:mah, GOC:vw] |
| GO:0090316 | positive regulation of intracellular protein transport | biological_process | Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. [GOC:tb] |
| GO:1901673 | regulation of mitotic spindle assembly | biological_process | Any process that modulates the frequency, rate or extent of mitotic spindle assembly. [GOC:TermGenie] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005635 | nuclear envelope | cellular_component | The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). [ISBN:0198547684] |
| GO:0005643 | nuclear pore | cellular_component | A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. [ISBN:0198547684] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0031965 | nuclear membrane | cellular_component | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. [GOC:mah, GOC:pz] |
| GO:0034399 | nuclear periphery | cellular_component | The portion of the nuclear lumen proximal to the inner nuclear membrane. [GOC:krc, GOC:mah] |
| GO:0042405 | nuclear inclusion body | cellular_component | An intranuclear focus at which aggregated proteins have been sequestered. [GOC:jl] |
| GO:0072686 | mitotic spindle | cellular_component | A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. [GOC:mah, GOC:vw, PMID:11408572, PMID:18367542, PMID:8027178] |
| GO:0005868 | cytoplasmic dynein complex | cellular_component | Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains. [GOC:cilia, GOC:hla, GOC:krc, GOC:mah, PMID:12600311] |
| GO:0044615 | nuclear pore nuclear basket | cellular_component | A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component. [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] |
| GO:0006406 | mRNA export from nucleus | biological_process | The directed movement of mRNA from the nucleus to the cytoplasm. [GOC:ma] |