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TRABD2B-202 ,TRABD2B ,A6NFA1
  • Uniprot Accession= A6NFA1
  • Ensembl Transcript= ENST00000606738.3
  • Uniprot Name= TRABD2B
  • Name= Metalloprotease TIKI2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 12
GO term GO name GO namespace GO def
GO:0004222 metalloendopeptidase activity molecular_function Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0017147 Wnt-protein binding molecular_function Binding to a Wnt-protein, a secreted growth factor involved in signaling. [GOC:jl]
GO:0046872 metal ion binding molecular_function Binding to a metal ion. [GOC:ai]
GO:0006508 proteolysis biological_process The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah]
GO:0016055 Wnt signaling pathway biological_process The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state. [PMID:11532397]
GO:0030178 negative regulation of Wnt signaling pathway biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway. [GOC:dph, GOC:go_curators, GOC:tb]
GO:0031334 positive regulation of protein-containing complex assembly biological_process Any process that activates or increases the frequency, rate or extent of protein complex assembly. [GOC:mah]
GO:1904808 positive regulation of protein oxidation biological_process Any process that activates or increases the frequency, rate or extent of protein oxidation. [GO_REF:0000058, GOC:TermGenie, PMID:22719267]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0031090 organelle membrane cellular_component A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. [GOC:dos, GOC:mah]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]