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TXNIP-204 ,TXNIP ,Q9H3M7
  • Uniprot Accession= Q9H3M7
  • Ensembl Transcript= ENST00000582401.6
  • Uniprot Name= TXNIP
  • Name= Thioredoxin-interacting protein
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 24
GO term GO name GO namespace GO def
GO:0004857 enzyme inhibitor activity molecular_function Binds to and stops, prevents or reduces the activity of an enzyme. [GOC:ai, GOC:ebc]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0031625 ubiquitin protein ligase binding molecular_function Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp]
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0006606 protein import into nucleus biological_process The directed movement of a protein from the cytoplasm to the nucleus. [GOC:jl]
GO:0006954 inflammatory response biological_process The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732]
GO:0007049 cell cycle biological_process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. [GOC:go_curators, GOC:mtg_cell_cycle]
GO:0009410 response to xenobiotic stimulus biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:jl, GOC:krc]
GO:0009612 response to mechanical stimulus biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. [GOC:hb]
GO:0009749 response to glucose biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. [GOC:jl]
GO:0030216 keratinocyte differentiation biological_process The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. [GOC:dph, GOC:mah, GOC:sdb_2009, GOC:tb]
GO:0032355 response to estradiol biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. [GOC:mah, ISBN:0911910123]
GO:0032570 response to progesterone biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. [GOC:sl]
GO:0042127 regulation of cell population proliferation biological_process Any process that modulates the frequency, rate or extent of cell proliferation. [GOC:jl]
GO:0042542 response to hydrogen peroxide biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. [GOC:jl]
GO:0043065 positive regulation of apoptotic process biological_process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0048008 platelet-derived growth factor receptor signaling pathway biological_process The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb]
GO:0051592 response to calcium ion biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. [GOC:ai]
GO:0051782 negative regulation of cell division biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. [GOC:ai]
GO:0071228 cellular response to tumor cell biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell. [GOC:mah]
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus. [GOC:aruk, GOC:BHF, PMID:20037584, PMID:27607416]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0015031 protein transport biological_process The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]