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URB2-201 ,URB2 ,Q14146
  • Uniprot Accession= Q14146
  • Ensembl Transcript= ENST00000258243.7
  • Uniprot Name= URB2
  • Name= Unhealthy ribosome biogenesis protein 2 homolog
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 5
GO term GO name GO namespace GO def
GO:1901796 regulation of signal transduction by p53 class mediator biological_process Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. [GOC:TermGenie]
GO:0005730 nucleolus cellular_component A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [ISBN:0198506732]
GO:0016235 aggresome cellular_component An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. [PMID:11121744]
GO:0030496 midbody cellular_component A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. [ISBN:0815316194]
GO:0042254 ribosome biogenesis biological_process A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis]