GO term | GO name | GO namespace | GO def |
GO:0004843 | cysteine-type deubiquitinase activity | molecular_function | An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated. [GOC:jh2, PMID:30783221] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0031625 | ubiquitin protein ligase binding | molecular_function | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp] |
GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
GO:0061578 | K63-linked deubiquitinase activity | molecular_function | Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys63 residue of ubiquitin. [GOC:dph, GOC:pg, PMID:18313383] |
GO:0101005 | deubiquitinase activity | molecular_function | An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated. [GOC:mec, PMID:30783221] |
GO:1990380 | K48-linked deubiquitinase activity | molecular_function | Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys48 residue of ubiquitin. [GOC:bf, GOC:PARL, PMID:22970133] |
GO:0016236 | macroautophagy | biological_process | The autophagic process that proceeds via the formation of an autophagosome. [PMID:24366339] |
GO:0036503 | ERAD pathway | biological_process | The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. [GOC:bf, GOC:PARL, PMID:20940304, PMID:21969857] |
GO:0030968 | endoplasmic reticulum unfolded protein response | biological_process | The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. [GOC:mah, PMID:12042763] |
GO:0035523 | protein K29-linked deubiquitination | biological_process | A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein. [GOC:bf] |
GO:0035871 | protein K11-linked deubiquitination | biological_process | A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein. [GOC:sp, PMID:21596315] |
GO:0070536 | protein K63-linked deubiquitination | biological_process | A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. [GOC:mah, PMID:19202061, PMID:19214193] |
GO:0071108 | protein K48-linked deubiquitination | biological_process | A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein. [GOC:mah] |
GO:1904153 | negative regulation of retrograde protein transport, ER to cytosol | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18555783] |
GO:1990167 | protein K27-linked deubiquitination | biological_process | A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein. [PMID:23827681] |
GO:1990168 | protein K33-linked deubiquitination | biological_process | A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein. [PMID:23827681] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
GO:0016579 | protein deubiquitination | biological_process | The removal of one or more ubiquitin groups from a protein. [GOC:ai] |