| GO term | GO name | GO namespace | GO def |
| GO:0001217 | DNA-binding transcription repressor activity | molecular_function | A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets. [GOC:txnOH-2018] |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | molecular_function | A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. [GOC:aruk, GOC:txnOH-2018, PMID:20737563, PMID:27145859] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0042803 | protein homodimerization activity | molecular_function | Binding to an identical protein to form a homodimer. [GOC:jl] |
| GO:0042826 | histone deacetylase binding | molecular_function | Binding to histone deacetylase. [GOC:jl] |
| GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
| GO:1990837 | sequence-specific double-stranded DNA binding | molecular_function | Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. [GOC:dos, GOC:sl] |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH] |
| GO:0001865 | NK T cell differentiation | biological_process | The process in which a precursor cell type acquires the specialized features of a NK T cell. [GOC:add, ISBN:0781735149, PMID:10704459] |
| GO:0006366 | transcription by RNA polymerase II | biological_process | The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). [GOC:jl, GOC:txnOH, ISBN:0321000382] |
| GO:0007398 | ectoderm development | biological_process | The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. [GOC:dph, GOC:tb] |
| GO:0007595 | lactation | biological_process | The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. [ISBN:0198506732] |
| GO:0010628 | positive regulation of gene expression | biological_process | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0010629 | negative regulation of gene expression | biological_process | Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0032740 | positive regulation of interleukin-17 production | biological_process | Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. [GOC:add, GOC:mah, PMID:16482511] |
| GO:0032868 | response to insulin | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732] |
| GO:0043372 | positive regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation. [GOC:add, GOC:pr, ISBN:0781735149] |
| GO:0043377 | negative regulation of CD8-positive, alpha-beta T cell differentiation | biological_process | Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation. [GOC:add, ISBN:0781735149] |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH] |
| GO:0046628 | positive regulation of insulin receptor signaling pathway | biological_process | Any process that increases the frequency, rate or extent of insulin receptor signaling. [GOC:bf] |
| GO:0051141 | negative regulation of NK T cell proliferation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation. [ISBN:0781735149, PMID:12154375, PMID:9133426] |
| GO:0090336 | positive regulation of brown fat cell differentiation | biological_process | Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. [GOC:BHF] |
| GO:0120162 | positive regulation of cold-induced thermogenesis | biological_process | Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis. [PMID:27876809] |
| GO:1990845 | adaptive thermogenesis | biological_process | The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. [PMID:17260010, PMID:20363363] |
| GO:2000320 | negative regulation of T-helper 17 cell differentiation | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. [GOC:BHF, GOC:mah] |
| GO:2000640 | positive regulation of SREBP signaling pathway | biological_process | Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway. [GOC:BHF] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0006357 | regulation of transcription by RNA polymerase II | biological_process | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH] |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | molecular_function | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. [GOC:txnOH-2018] |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. [GOC:txnOH-2018] |