GO term | GO name | GO namespace | GO def |
GO:0000993 | RNA polymerase II complex binding | molecular_function | Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits. [GOC:txnOH] |
GO:0003677 | DNA binding | molecular_function | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw] |
GO:0003723 | RNA binding | molecular_function | Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
GO:0006397 | mRNA processing | biological_process | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. [GOC:mah] |
GO:0008380 | RNA splicing | biological_process | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:krc, GOC:mah] |
GO:0032784 | regulation of DNA-templated transcription elongation | biological_process | Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. [GOC:mah, GOC:txnOH] |
GO:0043484 | regulation of RNA splicing | biological_process | Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:jl] |
GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
GO:0016363 | nuclear matrix | cellular_component | The dense fibrillar network lying on the inner side of the nuclear membrane. [ISBN:0582227089] |
GO:0043231 | intracellular membrane-bounded organelle | cellular_component | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators] |
GO:0044609 | DBIRD complex | cellular_component | A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD. [GOC:sp, PMID:22446626] |
GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |