Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCD1-201 | ABCD1 | P33897 | ATP-binding cassette sub-family D member 1 | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 72 | 75 | 4 | 4 | 100 |
| ABCD2-201 | ABCD2 | Q9UBJ2 | ATP-binding cassette sub-family D member 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 111 | 29 | 3 | 3 | 0 |
| ABCD3-202 | ABCD3 | P28288 | ATP-binding cassette sub-family D member 3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 21 | 1 | 1 | 0 |
| ACBD5-201 | ACBD5 | Q5T8D3 | Acyl-CoA-binding domain-containing protein 5 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 335 | 34 | 34 | 0 |
| AGPS-201 | AGPS | O00116 | Alkyldihydroxyacetonephosphate synthase, peroxisomal | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 152 | 11 | 11 | 6 |
| AKAP1-202 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 541 | 50 | 50 | 0 |
| ANKRD55-201 | ANKRD55 | Q3KP44 | Ankyrin repeat domain-containing protein 55 | chr5 | Not Cancer Driver | No | 1 | hippie | 72 | 340 | 48 | 48 | 0 |
| ANLN-201 | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 101 | 771 | 75 | 75 | 2 |
| AR-201 | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie | 116 | 443 | 38 | 38 | 144 |
| ARF6-201 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 5 | 0 | 0 | 0 |
| ARHGEF16-203 | ARHGEF16 | Q5VV41 | Rho guanine nucleotide exchange factor 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 299 | 10 | 10 | 0 |
| ATP2A1-201 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 80 | 9 | 9 | 1 |
| ATP2A3-205 | ATP2A3 | Q93084 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 92 | 147 | 13 | 13 | 0 |
| ATP2B2-202 | ATP2B2 | Q01814 | Plasma membrane calcium-transporting ATPase 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 206 | 362 | 68 | 68 | 0 |
| ATP6V1C1-202 | ATP6V1C1 | P21283 | V-type proton ATPase subunit C 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 17 | 2 | 2 | 0 |
| AURKAIP1-202 | AURKAIP1 | Q9NWT8 | Small ribosomal subunit protein mS38 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 104 | 8 | 8 | 0 |
| BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | Not Cancer Driver | No | 1 | hippie | 10 | 165 | 10 | 10 | 0 |
| BIRC3-201 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 53 | 98 | 10 | 10 | 0 |
| BRD7-201 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 1 | hippie | 58 | 485 | 33 | 33 | 0 |
| BRF2-201 | BRF2 | Q9HAW0 | Transcription factor IIIB 50 kDa subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 26 | 138 | 7 | 7 | 0 |
| BTRC-202 | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 45 | 3 | 3 | 0 |
| C15orf48-202 | NMES1 | Q9C002 | Normal mucosa of esophagus-specific gene 1 protein | chr15 | Not Cancer Driver | No | 1 | intact | 9 | 10 | 1 | 1 | 0 |
| CBX4-201 | CBX4 | O00257 | E3 SUMO-protein ligase CBX4 | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 479 | 39 | 39 | 0 |
| CCNF-202 | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 221 | 16 | 16 | 3 |
| CD274-202 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | Census | Yes | 1 | hippie | 26 | 54 | 9 | 9 | 0 |
| CDC34-201 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | Not Cancer Driver | No | 1 | hippie | 19 | 96 | 7 | 7 | 0 |
| CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| CDK9-201 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 40 | 34 | 2 | 2 | 0 |
| CFTR-201 | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | intact | 216 | 145 | 9 | 9 | 130 |
| CHMP4B-201 | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | Not Cancer Driver | No | 1 | hippie | 21 | 201 | 20 | 20 | 2 |
| CIT-201 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 196 | 1020 | 116 | 116 | 3 |
| CLK2-203 | CLK2 | P49760 | Dual specificity protein kinase CLK2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 151 | 19 | 19 | 0 |
| CLN3-243 | CLN3 | Q13286 | Battenin | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 69 | 5 | 5 | 8 |
| COL6A2-201 | COL6A2 | P12110 | Collagen alpha-2(VI) chain | chr21 | Not Cancer Driver | No | 1 | hippie | 176 | 465 | 77 | 77 | 10 |
| COQ9-201 | COQ9 | O75208 | Ubiquinone biosynthesis protein COQ9, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 25 | 111 | 5 | 5 | 0 |
| COX14-203 | COX14 | Q96I36 | Cytochrome c oxidase assembly protein COX14 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 4 | 7 | 0 | 0 | 1 |
| COX15-201 | COX15 | Q7KZN9 | Cytochrome c oxidase assembly protein COX15 homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 0 | 0 | 0 | 2 |
| COX6B1-204 | COX6B1 | P14854 | Cytochrome c oxidase subunit 6B1 | chr19 | Not Cancer Driver | No | 1 | hippie | 14 | 23 | 5 | 5 | 1 |
| CRELD1-206 | CRELD1 | Q96HD1 | Protein disulfide isomerase CRELD1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 44 | 6 | 6 | 4 |
| CTDNEP1-210 | CTDNEP1 | O95476 | CTD nuclear envelope phosphatase 1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 0 | 0 | 0 | 0 |
| CUL3-201 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 98 | 168 | 18 | 18 | 3 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 54 | 102 | 2 | 2 | 0 |
| DDR2-201 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | Census | Yes | 1 | biogrid | 129 | 120 | 25 | 25 | 7 |
| DDRGK1-201 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 26 | 181 | 19 | 19 | 0 |
| DEPDC1B-201 | DEPDC1B | Q8WUY9 | DEP domain-containing protein 1B | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 52 | 3 | 3 | 0 |
| DHX9-201 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie, biogrid | 125 | 332 | 30 | 30 | 0 |
| DOCK2-210 | DOCK2 | Q92608 | Dedicator of cytokinesis protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 382 | 267 | 71 | 71 | 2 |
| DOCK3-201 | DOCK3 | Q8IZD9 | Dedicator of cytokinesis protein 3 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 269 | 458 | 51 | 51 | 0 |
| DYRK1A-214 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | Not Cancer Driver | No | 1 | hippie | 3 | 447 | 1 | 1 | 0 |
| DYRK1B-201 | DYRK1B | Q9Y463 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | chr19 | Not Cancer Driver | No | 1 | hippie | 67 | 319 | 31 | 31 | 2 |
| ECT2-204 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 67 | 284 | 20 | 20 | 0 |
| EEF2-201 | EEF2 | P13639 | Elongation factor 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 79 | 9 | 9 | 1 |
| EFTUD2-202 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 100 | 179 | 22 | 22 | 3 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 346 | 223 | 30 | 30 | 1 |
| EGLN3-201 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 0 | 0 | 0 |
| ENST00000636766 | CLN3 | Q13286 | Battenin | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 0 | 0 | 0 | 0 | 0 |
| ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 203 | 1792 | 84 | 84 | 1 |
| EPHA1-201 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | Not Cancer Driver | No | 1 | intact, biogrid | 109 | 211 | 29 | 29 | 0 |
| ESR1-201 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 92 | 198 | 19 | 19 | 2 |
| ESR2-202 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 69 | 92 | 10 | 10 | 1 |
| EXD2-214 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 178 | 12 | 12 | 0 |
| FAF2-201 | FAF2 | Q96CS3 | FAS-associated factor 2 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 171 | 11 | 11 | 0 |
| FBXO6-201 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 25 | 27 | 3 | 3 | 0 |
| FBXW7-201 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 289 | 232 | 15 | 15 | 17 |
| FIS1-201 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 6 | 0 | 0 | 0 |
| FKBP8-206 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 161 | 19 | 19 | 0 |
| GNAO1-201 | GNAO1 | P09471 | Guanine nucleotide-binding protein G(o) subunit alpha | chr16 | Not Cancer Driver | No | 1 | hippie | 29 | 10 | 0 | 0 | 14 |
| GOLT1B-201 | GOLT1B | Q9Y3E0 | Vesicle transport protein GOT1B | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 0 | 0 | 0 | 0 |
| GPR182-201 | GPR182 | O15218 | G-protein coupled receptor 182 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 33 | 5 | 5 | 0 |
| HAX1-201 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 219 | 23 | 23 | 2 |
| HIF1AN-201 | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 24 | 78 | 5 | 5 | 0 |
| HIPK4-201 | HIPK4 | Q8NE63 | Homeodomain-interacting protein kinase 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 65 | 260 | 21 | 21 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 129 | 16 | 2 | 2 | 10 |
| HSD17B11-201 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 2 | 0 | 0 | 0 |
| HSD3B7-202 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 27 | 4 | 4 | 2 |
| HSPB1-201 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 19 |
| INS-202 | INS | P01308 | Insulin | chr11 | Not Cancer Driver | No | 1 | hippie | 7 | 5 | 1 | 1 | 19 |
| JUN-201 | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 26 | 283 | 17 | 17 | 0 |
| KIF14-201 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 145 | 777 | 65 | 65 | 2 |
| KIF20A-201 | KIF20A | O95235 | Kinesin-like protein KIF20A | chr5 | Not Cancer Driver | No | 1 | hippie | 64 | 341 | 32 | 32 | 1 |
| KIF23-201 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | Not Cancer Driver | No | 1 | hippie | 74 | 561 | 45 | 45 | 1 |
| KLF15-201 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 46 | 273 | 29 | 29 | 0 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 3 | intact, hippie, biogrid | 771 | 7 | 2 | 2 | 22 |
| KRT18-201 | KRT18 | P05783 | Keratin, type I cytoskeletal 18 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 179 | 17 | 17 | 4 |
| LACC1-201 | LACC1 | Q8IV20 | Purine nucleoside phosphorylase LACC1 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 4 | 0 | 0 | 1 |
| LMAN1-201 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 223 | 18 | 18 | 1 |
| LMBR1L-201 | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 4 | 0 | 0 | 0 |
| MAPK6-201 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 52 | 166 | 13 | 13 | 0 |
| MARCKS-201 | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 328 | 5 | 5 | 0 |
| MAVS-202 | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 415 | 44 | 44 | 0 |
| MDC1-201 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 175 | 1829 | 156 | 156 | 0 |
| MECOM-217 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | Census, Compendium | Yes | 1 | hippie | 225 | 751 | 120 | 120 | 3 |
| MEST-201 | MEST | Q5EB52 | Mesoderm-specific transcript homolog protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 0 | 0 | 0 | 0 |
| MEX3C-201 | MEX3C | Q5U5Q3 | RNA-binding E3 ubiquitin-protein ligase MEX3C | chr18 | Not Cancer Driver | No | 1 | intact | 36 | 476 | 23 | 23 | 0 |
| MGST3-205 | MGST3 | O14880 | Glutathione S-transferase 3, mitochondrial | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 0 | 0 | 0 | 0 |
| MKI67-202 | MKI67 | P46013 | Proliferation marker protein Ki-67 | chr10 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 346 | 3213 | 343 | 343 | 0 |
| MLF2-201 | MLF2 | Q15773 | Myeloid leukemia factor 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 189 | 27 | 27 | 0 |
| MMS19-209 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | Not Cancer Driver | No | 1 | hippie | 54 | 11 | 0 | 0 | 0 |
| MOV10-203 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 90 | 103 | 6 | 6 | 0 |
| MPV17-203 | MPV17 | P39210 | Protein Mpv17 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 0 | 0 | 0 | 15 |
| MRPL41-201 | MRPL41 | Q8IXM3 | Large ribosomal subunit protein mL41 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 23 | 0 | 0 | 0 |
| MTCH1-202 | MTCH1 | Q9NZJ7 | Mitochondrial carrier homolog 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 102 | 1 | 1 | 0 |
| MTCH2-201 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 11 | 0 | 0 | 0 |
| MYC-206 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 72 | 325 | 41 | 41 | 0 |
| MYH14-204 | MYH14 | Q7Z406 | Myosin-14 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 204 | 1220 | 128 | 128 | 5 |
| NAA40-202 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 31 | 1 | 1 | 0 |
| NDN-201 | NDN | Q99608 | Necdin | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 119 | 117 | 40 | 40 | 0 |
| NDUFA4-201 | NDUFA4 | O00483 | Cytochrome c oxidase subunit NDUFA4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 4 | 0 | 0 | 0 |
| NDUFAF4-201 | NDUFAF4 | Q9P032 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 8 | 47 | 3 | 3 | 2 |
| NDUFAF8-201 | NDUFAF8 | A1L188 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 | chr17 | Not Cancer Driver | No | 1 | hippie | 0 | 0 | 0 | 0 | 0 |
| NDUFB11-202 | NDUFB11 | Q9NX14 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 51 | 6 | 6 | 1 |
| NDUFS4-201 | NDUFS4 | O43181 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 93 | 12 | 12 | 1 |
| NDUFV1-201 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 57 | 3 | 3 | 3 |
| NEFM-201 | NEFM | P07197 | Neurofilament medium polypeptide | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 768 | 49 | 49 | 0 |
| NET1-201 | NET1 | Q7Z628 | Neuroepithelial cell-transforming gene 1 protein | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 297 | 32 | 32 | 0 |
| NNT-202 | NNT | Q13423 | NAD(P) transhydrogenase, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 47 | 5 | 5 | 11 |
| NR2C2-206 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 41 | 187 | 13 | 13 | 0 |
| NRAS-201 | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 272 | 10 | 0 | 0 | 12 |
| NTRK1-206 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 133 | 57 | 8 | 8 | 23 |
| NUDCD1-201 | NUDCD1 | Q96RS6 | NudC domain-containing protein 1 | chr8 | Not Cancer Driver | No | 1 | intact | 49 | 38 | 2 | 2 | 0 |
| NUP155-201 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 128 | 221 | 17 | 17 | 1 |
| NXF1-201 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 85 | 163 | 28 | 28 | 0 |
| OBSL1-204 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 168 | 556 | 38 | 38 | 0 |
| OCIAD1-201 | OCIAD1 | Q9NX40 | OCIA domain-containing protein 1 | chr4 | Not Cancer Driver | No | 2 | hippie, biogrid | 25 | 169 | 19 | 19 | 0 |
| OPA3-201 | OPA3 | Q9H6K4 | Optic atrophy 3 protein | chr19 | Not Cancer Driver | No | 1 | hippie | 3 | 44 | 0 | 0 | 2 |
| PBXIP1-202 | PBXIP1 | Q96AQ6 | Pre-B-cell leukemia transcription factor-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 606 | 60 | 60 | 0 |
| PCM1-201 | PCM1 | Q15154 | Pericentriolar material 1 protein | chr8 | Census | Yes | 1 | intact, hippie | 104 | 1673 | 94 | 94 | 0 |
| PDHA1-205 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 43 | 4 | 4 | 19 |
| PELO-201 | PELO | Q9BRX2 | Protein pelota homolog | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 27 | 67 | 6 | 6 | 0 |
| PEX14-201 | PEX14 | O75381 | Peroxisomal membrane protein PEX14 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 28 | 268 | 19 | 19 | 0 |
| PEX19-201 | PEX19 | P40855 | Peroxisomal biogenesis factor 19 | chr1 | Not Cancer Driver | No | 4 | intact, hippie | 26 | 267 | 23 | 23 | 0 |
| PEX3-201 | PEX3 | P56589 | Peroxisomal biogenesis factor 3 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 24 | 0 | 0 | 2 |
| PGRMC1-201 | PGRMC1 | O00264 | Membrane-associated progesterone receptor component 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 74 | 11 | 11 | 0 |
| PHYH-201 | PHYH | O14832 | Phytanoyl-CoA dioxygenase, peroxisomal | chr10 | Not Cancer Driver | No | 1 | hippie | 34 | 41 | 2 | 2 | 14 |
| PIM3-201 | PIM3 | Q86V86 | Serine/threonine-protein kinase pim-3 | chr22 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 22 | 9 | 0 | 0 | 0 |
| PLEKHA4-201 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 115 | 690 | 110 | 110 | 0 |
| PLGRKT-201 | PLGRKT | Q9HBL7 | Plasminogen receptor (KT) | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 0 | 0 | 0 | 0 |
| PRC1-202 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 44 | 236 | 17 | 17 | 0 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | Census | Yes | 1 | hippie | 164 | 190 | 31 | 31 | 2 |
| PSMA1-201 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 51 | 7 | 7 | 0 |
| PSMD14-201 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 1 | hippie | 14 | 68 | 3 | 3 | 0 |
| PTP4A3-204 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 27 | 3 | 0 | 0 | 0 |
| PTPN1-201 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 36 | 141 | 17 | 17 | 0 |
| PTRH2-201 | PTRH2 | Q9Y3E5 | Peptidyl-tRNA hydrolase 2, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 7 | 19 | 1 | 1 | 1 |
| PXMP2-201 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 0 | 0 | 0 | 0 |
| PYHIN1-203 | PYHIN1 | Q6K0P9 | Pyrin and HIN domain-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 139 | 293 | 81 | 81 | 0 |
| RAB11A-201 | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 43 | 2 | 2 | 0 |
| RAB2A-201 | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 58 | 3 | 3 | 0 |
| RAB35-201 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 26 | 1 | 1 | 0 |
| RAB3B-201 | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 26 | 6 | 6 | 0 |
| RAB4A-201 | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 32 | 8 | 8 | 0 |
| RAB5A-201 | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 20 | 67 | 9 | 9 | 0 |
| RAB5C-201 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 51 | 2 | 2 | 0 |
| RAB5IF-203 | RAB5IF | Q9BUV8 | GEL complex subunit OPTI | chr20 | Not Cancer Driver | No | 1 | hippie | 1 | 13 | 0 | 0 | 0 |
| RAB7A-201 | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 19 | 11 | 0 | 0 | 4 |
| RAB9A-202 | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 7 | 21 | 0 | 0 | 0 |
| RAC2-201 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 2 |
| RAC3-201 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 4 |
| RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | Census, Compendium | Yes | 1 | intact, hippie | 64 | 169 | 30 | 30 | 18 |
| RECQL4-209 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 105 | 612 | 54 | 54 | 1 |
| RETREG2-203 | RETREG2 | Q8NC44 | Reticulophagy regulator 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 321 | 32 | 32 | 0 |
| RHOA-202 | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 92 | 46 | 12 | 12 | 2 |
| RHOC-202 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 53 | 4 | 4 | 0 |
| RHOD-201 | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 10 | 0 | 0 | 0 |
| RHOG-201 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 22 | 3 | 3 | 0 |
| RHOH-201 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 32 | 12 | 3 | 3 | 0 |
| RHOT2-201 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 81 | 4 | 4 | 0 |
| RIPK4-202 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 99 | 232 | 31 | 31 | 3 |
| RMDN3-202 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 198 | 14 | 14 | 0 |
| RND2-202 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 17 | 54 | 4 | 4 | 0 |
| RNF123-201 | RNF123 | Q5XPI4 | E3 ubiquitin-protein ligase RNF123 | chr3 | Not Cancer Driver | No | 1 | hippie | 126 | 220 | 23 | 23 | 0 |
| RNF2-202 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 26 | 203 | 15 | 15 | 1 |
| RNF4-201 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 9 | 120 | 5 | 5 | 0 |
| RTRAF-201 | RTRAF | Q9Y224 | RNA transcription, translation and transport factor protein | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 35 | 0 | 0 | 0 |
| RYBP-201 | RYBP | Q8N488 | RING1 and YY1-binding protein | chr3 | Not Cancer Driver | No | 1 | hippie | 23 | 202 | 22 | 22 | 0 |
| SCARB2-201 | SCARB2 | Q14108 | Lysosome membrane protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 46 | 13 | 3 | 3 | 1 |
| SCN3B-201 | SCN3B | Q9NY72 | Sodium channel subunit beta-3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 16 | 2 | 2 | 3 |
| SEC61B-201 | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 60 | 5 | 5 | 0 |
| SEC63-201 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 267 | 25 | 25 | 0 |
| SFXN1-201 | SFXN1 | Q9H9B4 | Sideroflexin-1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 29 | 0 | 0 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 24 | 165 | 6 | 6 | 0 |
| SLC16A11-202 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 25 | 48 | 3 | 3 | 0 |
| SLC25A46-201 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 98 | 2 | 2 | 4 |
| SLC39A4-202 | SLC39A4 | Q6P5W5 | Zinc transporter ZIP4 | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 58 | 116 | 9 | 9 | 9 |
| SMIM26-201 | SMIM26 | A0A096LP01 | Small integral membrane protein 26 | chr20 | Not Cancer Driver | No | 1 | intact | 0 | 17 | 0 | 0 | 0 |
| SNAI1-201 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 41 | 98 | 8 | 8 | 0 |
| SOX4-201 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 402 | 20 | 20 | 4 |
| SP1-201 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 601 | 53 | 53 | 0 |
| SP7-202 | SP7 | Q8TDD2 | Transcription factor Sp7 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 46 | 332 | 32 | 32 | 0 |
| SPRTN-202 | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 53 | 254 | 26 | 26 | 1 |
| STARD8-202 | STARD8 | Q92502 | StAR-related lipid transfer protein 8 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 579 | 70 | 70 | 0 |
| STAU1-207 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 54 | 458 | 45 | 45 | 0 |
| STOM-201 | STOM | P27105 | Stomatin | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 18 | 44 | 2 | 2 | 0 |
| SUB1-201 | SUB1 | P53999 | Activated RNA polymerase II transcriptional coactivator p15 | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 108 | 4 | 4 | 0 |
| SURF1-201 | SURF1 | Q15526 | Surfeit locus protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 82 | 5 | 5 | 9 |
| SYNJ2BP-201 | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 12 | 1 | 1 | 0 |
| TAP1-201 | TAP1 | Q03518 | Antigen peptide transporter 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 42 | 2 | 2 | 0 |
| TFCP2-201 | TFCP2 | Q12800 | Alpha-globin transcription factor CP2 | chr12 | Not Cancer Driver | No | 1 | hippie | 40 | 169 | 12 | 12 | 0 |
| TFDP1-201 | TFDP1 | Q14186 | Transcription factor Dp-1 | chr13 | Not Cancer Driver | No | 1 | hippie | 61 | 246 | 36 | 36 | 0 |
| TIMMDC1-208 | TIMMDC1 | Q9NPL8 | Complex I assembly factor TIMMDC1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 51 | 4 | 4 | 0 |
| TMEM41B-204 | TMEM41B | Q5BJD5 | Transmembrane protein 41B | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 48 | 2 | 2 | 0 |
| TMEM63B-202 | TMEM63B | Q5T3F8 | CSC1-like protein 2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 80 | 78 | 11 | 11 | 0 |
| TMEM67-205 | TMEM67 | Q5HYA8 | Meckelin | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 11 | 0 | 0 | 45 |
| TOMM20-201 | TOMM20 | Q15388 | Mitochondrial import receptor subunit TOM20 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 6 | 25 | 0 | 0 | 0 |
| TOMM22-201 | TOMM22 | Q9NS69 | Mitochondrial import receptor subunit TOM22 homolog | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 83 | 5 | 5 | 0 |
| TOMM40-203 | TOMM40 | O96008 | Mitochondrial import receptor subunit TOM40 homolog | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 98 | 0 | 0 | 0 |
| TPTE-204 | TPTE | P56180 | Putative tyrosine-protein phosphatase TPTE | chr21 | Not Cancer Driver | No | 1 | hippie | 422 | 48 | 41 | 41 | 0 |
| TRIM25-201 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 226 | 11 | 11 | 0 |
| TRIM28-201 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 67 | 431 | 32 | 32 | 0 |
| TRIM37-201 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 89 | 493 | 42 | 42 | 3 |
| TUFT1-202 | TUFT1 | Q9NNX1 | Tuftelin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 296 | 25 | 25 | 0 |
| UBE2A-202 | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | Compendium | Yes | 1 | hippie | 23 | 67 | 11 | 11 | 2 |
| UBQLN2-201 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 1 | hippie | 64 | 581 | 61 | 61 | 8 |
| UFL1-201 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 77 | 141 | 19 | 19 | 0 |
| UNK-205 | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 60 | 513 | 33 | 33 | 0 |
| USP11-201 | USP11 | P51784 | Ubiquitin carboxyl-terminal hydrolase 11 | chrX | Not Cancer Driver | No | 1 | hippie | 104 | 211 | 21 | 21 | 0 |
| USP32-201 | USP32 | Q8NFA0 | Ubiquitin carboxyl-terminal hydrolase 32 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 128 | 401 | 35 | 35 | 0 |
| USP50-203 | USP50 | Q70EL3 | Inactive ubiquitin carboxyl-terminal hydrolase 50 | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 24 | 2 | 0 | 0 | 0 |
| VAPA-202 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 184 | 11 | 11 | 0 |
| VAV1-210 | VAV1 | P15498 | Proto-oncogene vav | chr19 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 128 | 113 | 18 | 18 | 0 |
| YAP1-201 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 41 | 491 | 41 | 41 | 0 |
| ZBTB2-201 | ZBTB2 | Q8N680 | Zinc finger and BTB domain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 64 | 216 | 29 | 29 | 0 |
| ZFPL1-201 | ZFPL1 | O95159 | Zinc finger protein-like 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 127 | 16 | 16 | 0 |
| ZNF454-202 | ZNF454 | Q8N9F8 | Zinc finger protein 454 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 152 | 22 | 22 | 0 |
| ZNF746-201 | ZNF746 | Q6NUN9 | Zinc finger protein 746 | chr7 | Not Cancer Driver | No | 1 | hippie | 68 | 437 | 43 | 43 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|