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ABCD3-202 ,ABCD3 ,P28288
  • Number of Interaction partner in intact: 52
  • Number of Interaction partner in biogrid: 89
  • Number of Interaction partner in hippie: 219
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCD1-201 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX Not Cancer Driver No 2 intact, hippie, biogrid 72 75 4 4 100
ABCD2-201 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 Not Cancer Driver No 1 hippie 111 29 3 3 0
ABCD3-202 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 intact, hippie 52 21 1 1 0
ACBD5-201 ACBD5 Q5T8D3 Acyl-CoA-binding domain-containing protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 49 335 34 34 0
AGPS-201 AGPS O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal chr2 Not Cancer Driver No 1 hippie, biogrid 56 152 11 11 6
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
ANKRD55-201 ANKRD55 Q3KP44 Ankyrin repeat domain-containing protein 55 chr5 Not Cancer Driver No 1 hippie 72 340 48 48 0
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 101 771 75 75 2
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 116 443 38 38 144
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 16 5 0 0 0
ARHGEF16-203 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 Not Cancer Driver No 1 hippie, biogrid 55 299 10 10 0
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
ATP2A3-205 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 92 147 13 13 0
ATP2B2-202 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 206 362 68 68 0
ATP6V1C1-202 ATP6V1C1 P21283 V-type proton ATPase subunit C 1 chr8 Not Cancer Driver No 1 hippie, biogrid 41 17 2 2 0
AURKAIP1-202 AURKAIP1 Q9NWT8 Small ribosomal subunit protein mS38 chr1 Not Cancer Driver No 1 hippie 17 104 8 8 0
BAD-201 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 10 165 10 10 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BRD7-201 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 58 485 33 33 0
BRF2-201 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 Not Cancer Driver No 1 hippie 26 138 7 7 0
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 57 45 3 3 0
C15orf48-202 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 9 10 1 1 0
CBX4-201 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 47 479 39 39 0
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CD274-202 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 26 54 9 9 0
CDC34-201 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 19 96 7 7 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 40 34 2 2 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHMP4B-201 CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 21 201 20 20 2
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CLK2-203 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 Not Cancer Driver No 1 hippie, biogrid 76 151 19 19 0
CLN3-243 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 intact, hippie 42 69 5 5 8
COL6A2-201 COL6A2 P12110 Collagen alpha-2(VI) chain chr21 Not Cancer Driver No 1 hippie 176 465 77 77 10
COQ9-201 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 25 111 5 5 0
COX14-203 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
COX15-201 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 2
COX6B1-204 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 14 23 5 5 1
CRELD1-206 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie, biogrid 28 44 6 6 4
CTDNEP1-210 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 Not Cancer Driver No 1 intact, hippie 12 0 0 0 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 98 168 18 18 3
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 54 102 2 2 0
DDR2-201 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 Census Yes 1 biogrid 129 120 25 25 7
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DEPDC1B-201 DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 Not Cancer Driver No 1 hippie, biogrid 54 52 3 3 0
DHX9-201 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie, biogrid 125 332 30 30 0
DOCK2-210 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 382 267 71 71 2
DOCK3-201 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 269 458 51 51 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
DYRK1B-201 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 Not Cancer Driver No 1 hippie 67 319 31 31 2
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EEF2-201 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 86 79 9 9 1
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ENST00000636766 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 intact, hippie 0 0 0 0 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPHA1-201 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact, biogrid 109 211 29 29 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
EXD2-214 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 47 178 12 12 0
FAF2-201 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 intact, hippie 36 171 11 11 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 289 232 15 15 17
FIS1-201 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 Not Cancer Driver No 1 hippie, biogrid 9 6 0 0 0
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 50 161 19 19 0
GNAO1-201 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 29 10 0 0 14
GOLT1B-201 GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 intact, hippie 14 0 0 0 0
GPR182-201 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 38 33 5 5 0
HAX1-201 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 219 23 23 2
HIF1AN-201 HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 24 78 5 5 0
HIPK4-201 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 Not Cancer Driver No 1 hippie 65 260 21 21 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 129 16 2 2 10
HSD17B11-201 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
HSD3B7-202 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 37 27 4 4 2
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 19
INS-202 INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 7 5 1 1 19
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
KLF15-201 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 46 273 29 29 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 3 intact, hippie, biogrid 771 7 2 2 22
KRT18-201 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie, biogrid 46 179 17 17 4
LACC1-201 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 Not Cancer Driver No 1 intact, hippie 40 4 0 0 1
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 50 223 18 18 1
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
MAPK6-201 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 52 166 13 13 0
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 5 328 5 5 0
MAVS-202 MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie, biogrid 55 415 44 44 0
MDC1-201 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 175 1829 156 156 0
MECOM-217 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 225 751 120 120 3
MEST-201 MEST Q5EB52 Mesoderm-specific transcript homolog protein chr7 Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 0
MEX3C-201 MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 1 intact 36 476 23 23 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MKI67-202 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 346 3213 343 343 0
MLF2-201 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 32 189 27 27 0
MMS19-209 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 54 11 0 0 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MPV17-203 MPV17 P39210 Protein Mpv17 chr2 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 15
MRPL41-201 MRPL41 Q8IXM3 Large ribosomal subunit protein mL41 chr9 Not Cancer Driver No 1 hippie, biogrid 14 23 0 0 0
MTCH1-202 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 21 102 1 1 0
MTCH2-201 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYH14-204 MYH14 Q7Z406 Myosin-14 chr19 Not Cancer Driver No 1 intact, hippie 204 1220 128 128 5
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 119 117 40 40 0
NDUFA4-201 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 8 4 0 0 0
NDUFAF4-201 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 1 hippie 8 47 3 3 2
NDUFAF8-201 NDUFAF8 A1L188 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 chr17 Not Cancer Driver No 1 hippie 0 0 0 0 0
NDUFB11-202 NDUFB11 Q9NX14 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 20 51 6 6 1
NDUFS4-201 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 18 93 12 12 1
NDUFV1-201 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 45 57 3 3 3
NEFM-201 NEFM P07197 Neurofilament medium polypeptide chr8 Not Cancer Driver No 1 hippie, biogrid 75 768 49 49 0
NET1-201 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 Not Cancer Driver No 1 hippie, biogrid 48 297 32 32 0
NNT-202 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 96 47 5 5 11
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUDCD1-201 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact 49 38 2 2 0
NUP155-201 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 128 221 17 17 1
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 25 169 19 19 0
OPA3-201 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 3 44 0 0 2
PBXIP1-202 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 69 606 60 60 0
PCM1-201 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 intact, hippie 104 1673 94 94 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PELO-201 PELO Q9BRX2 Protein pelota homolog chr5 Not Cancer Driver No 1 intact, hippie, biogrid 27 67 6 6 0
PEX14-201 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 2 hippie, biogrid 28 268 19 19 0
PEX19-201 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 4 intact, hippie 26 267 23 23 0
PEX3-201 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 2 hippie, biogrid 18 24 0 0 2
PGRMC1-201 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie, biogrid 23 74 11 11 0
PHYH-201 PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 Not Cancer Driver No 1 hippie 34 41 2 2 14
PIM3-201 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 22 9 0 0 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLGRKT-201 PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 11 0 0 0 0
PRC1-202 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 44 236 17 17 0
PRKD1-201 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 164 190 31 31 2
PSMA1-201 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 intact, hippie 33 51 7 7 0
PSMD14-201 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 14 68 3 3 0
PTP4A3-204 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 27 3 0 0 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 36 141 17 17 0
PTRH2-201 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie 7 19 1 1 1
PXMP2-201 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
PYHIN1-203 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 139 293 81 81 0
RAB11A-201 RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 12 43 2 2 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 15 58 3 3 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RAB3B-201 RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 26 26 6 6 0
RAB4A-201 RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 15 32 8 8 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 2 intact, hippie, biogrid 20 67 9 9 0
RAB5C-201 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 17 51 2 2 0
RAB5IF-203 RAB5IF Q9BUV8 GEL complex subunit OPTI chr20 Not Cancer Driver No 1 hippie 1 13 0 0 0
RAB7A-201 RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 2 intact, hippie, biogrid 19 11 0 0 4
RAB9A-202 RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 2 intact, hippie, biogrid 7 21 0 0 0
RAC2-201 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 24 0 0 0 2
RAC3-201 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 4
RAF1-201 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact, hippie 64 169 30 30 18
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RETREG2-203 RETREG2 Q8NC44 Reticulophagy regulator 2 chr2 Not Cancer Driver No 1 intact, hippie 48 321 32 32 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 16 10 0 0 0
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RHOH-201 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 32 12 3 3 0
RHOT2-201 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 40 81 4 4 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 99 232 31 31 3
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 33 198 14 14 0
RND2-202 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 17 54 4 4 0
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 26 203 15 15 1
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RTRAF-201 RTRAF Q9Y224 RNA transcription, translation and transport factor protein chr14 Not Cancer Driver No 1 intact, hippie 13 35 0 0 0
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SCARB2-201 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 46 13 3 3 1
SCN3B-201 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 hippie, biogrid 45 16 2 2 3
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 6 60 5 5 0
SEC63-201 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 67 267 25 25 0
SFXN1-201 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 29 0 0 0
SIRT6-202 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 24 165 6 6 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLC25A46-201 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 28 98 2 2 4
SLC39A4-202 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 2 hippie, biogrid 58 116 9 9 9
SMIM26-201 SMIM26 A0A096LP01 Small integral membrane protein 26 chr20 Not Cancer Driver No 1 intact 0 17 0 0 0
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 41 98 8 8 0
SOX4-201 SOX4 Q06945 Transcription factor SOX-4 chr6 Not Cancer Driver No 1 intact, hippie 25 402 20 20 4
SP1-201 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 intact, hippie 67 601 53 53 0
SP7-202 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 46 332 32 32 0
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 53 254 26 26 1
STARD8-202 STARD8 Q92502 StAR-related lipid transfer protein 8 chrX Not Cancer Driver No 1 hippie, biogrid 114 579 70 70 0
STAU1-207 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 54 458 45 45 0
STOM-201 STOM P27105 Stomatin chr9 Not Cancer Driver No 2 intact, hippie 18 44 2 2 0
SUB1-201 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie 8 108 4 4 0
SURF1-201 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 14 82 5 5 9
SYNJ2BP-201 SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 Not Cancer Driver No 1 hippie, biogrid 21 12 1 1 0
TAP1-201 TAP1 Q03518 Antigen peptide transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 52 42 2 2 0
TFCP2-201 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 40 169 12 12 0
TFDP1-201 TFDP1 Q14186 Transcription factor Dp-1 chr13 Not Cancer Driver No 1 hippie 61 246 36 36 0
TIMMDC1-208 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 37 51 4 4 0
TMEM41B-204 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 16 48 2 2 0
TMEM63B-202 TMEM63B Q5T3F8 CSC1-like protein 2 chr6 Not Cancer Driver No 1 intact, hippie 80 78 11 11 0
TMEM67-205 TMEM67 Q5HYA8 Meckelin chr8 Not Cancer Driver No 1 intact, hippie 85 11 0 0 45
TOMM20-201 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 6 25 0 0 0
TOMM22-201 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 intact, hippie 11 83 5 5 0
TOMM40-203 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 15 98 0 0 0
TPTE-204 TPTE P56180 Putative tyrosine-protein phosphatase TPTE chr21 Not Cancer Driver No 1 hippie 422 48 41 41 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 89 493 42 42 3
TUFT1-202 TUFT1 Q9NNX1 Tuftelin chr1 Not Cancer Driver No 1 intact, hippie 35 296 25 25 0
UBE2A-202 UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 23 67 11 11 2
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 64 581 61 61 8
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UNK-205 UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 60 513 33 33 0
USP11-201 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 104 211 21 21 0
USP32-201 USP32 Q8NFA0 Ubiquitin carboxyl-terminal hydrolase 32 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 128 401 35 35 0
USP50-203 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 24 2 0 0 0
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 intact, hippie 20 184 11 11 0
VAV1-210 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 intact, hippie, biogrid 128 113 18 18 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
ZBTB2-201 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 64 216 29 29 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 127 16 16 0
ZNF454-202 ZNF454 Q8N9F8 Zinc finger protein 454 chr5 Not Cancer Driver No 1 hippie, biogrid 84 152 22 22 0
ZNF746-201 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 68 437 43 43 0