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ACADM-202 ,ACADM ,P11310
  • Number of Interaction partner in intact: 2
  • Number of Interaction partner in biogrid: 71
  • Number of Interaction partner in hippie: 122
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AASS-203 AASS Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 124 18 3 3 0
ACAA2-201 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 32 52 1 1 0
ACAD9-201 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 54 28 2 2 12
ACADM-202 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 Not Cancer Driver No 2 intact, hippie 39 42 2 2 19
AHSA1-201 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 33 147 14 14 0
ALDH9A1-201 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 Not Cancer Driver No 1 hippie, biogrid 38 14 1 1 0
ANG-202 ANG P03950 Angiogenin chr14 Not Cancer Driver No 1 hippie 11 36 2 2 13
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 101 771 75 75 2
AP1M1-201 AP1M1 Q9BXS5 AP-1 complex subunit mu-1 chr19 Not Cancer Driver No 1 hippie, biogrid 55 38 11 11 0
ARF1-201 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 22 4 2 2 2
ARF4-201 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 0
ARF5-201 ARF5 P84085 ADP-ribosylation factor 5 chr7 Not Cancer Driver No 1 hippie, biogrid 15 11 1 1 0
ATP1A1-201 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie, biogrid 76 115 14 14 6
ATP5F1C-202 ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 27 11 0 0 0
ATP6V1A-201 ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 65 31 0 0 4
ATP9A-202 ATP9A O75110 Probable phospholipid-transporting ATPase IIA chr20 Not Cancer Driver No 1 hippie, biogrid 138 69 14 14 0
ATPAF1-211 ATPAF1 Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 24 47 4 4 0
AURKB-214 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 31 63 4 4 0
BCAT1-201 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 1 hippie, biogrid 53 8 2 2 0
BRD7-201 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 58 485 33 33 0
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 12 115 10 10 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 Not Cancer Driver No 1 hippie 13 115 8 8 6
CAND1-208 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 118 88 6 6 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 57 334 36 36 0
CCT6B-201 CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 1 hippie, biogrid 60 1 0 0 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CLPP-201 CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 15 83 7 7 3
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 38 13 2 2 0
CTSD-201 CTSD P07339 Cathepsin D chr11 Not Cancer Driver No 1 hippie, biogrid 49 6 2 2 2
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 98 168 18 18 3
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 20 13 3 3 1
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DDX39B-202 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie, biogrid 36 34 6 6 0
DIABLO-207 DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 20 54 2 2 1
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 106 520 65 65 0
DNAJA1-201 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 29 154 13 13 0
DYNC1I1-201 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 125 256 51 51 0
ECHS1-201 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 31 7 1 1 14
ENST00000647960 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 26 15 1 1 8
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
ETFA-203 ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 18 34 0 0 3
ETFB-201 ETFB P38117 Electron transfer flavoprotein subunit beta chr19 Not Cancer Driver No 1 hippie 29 38 5 5 2
FAF2-201 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 36 171 11 11 0
FAXC-201 FAXC Q5TGI0 Failed axon connections homolog chr6 Not Cancer Driver No 1 hippie, biogrid 37 54 6 6 0
FH-201 FH P07954 Fumarate hydratase, mitochondrial chr1 Census, Compendium Yes 1 hippie, biogrid 54 76 4 4 13
FLNC-201 FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 436 1451 234 234 7
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GALE-216 GALE Q14376 UDP-glucose 4-epimerase chr1 Not Cancer Driver No 1 hippie, biogrid 25 24 2 2 16
GFPT1-201 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 Not Cancer Driver No 1 hippie, biogrid 59 75 5 5 12
GFPT2-201 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 Not Cancer Driver No 1 hippie, biogrid 90 42 8 8 0
HDAC1-201 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 135 5 5 0
HIBCH-201 HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 31 26 0 0 1
HMOX2-208 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 17 74 5 5 0
HSP90B1-201 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 56 269 17 17 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie, biogrid 50 352 21 21 0
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 19
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 45 83 1 1 2
IDH3A-201 IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 24 47 8 8 0
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
LDHA-205 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 25 9 0 0 0
LDHB-201 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 32 15 1 1 10
LRPPRC-201 LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 99 18 0 0 1
MCUR1-201 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 66 0 0 0
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 26 8 1 1 3
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MECOM-217 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 225 751 120 120 3
MEPCE-201 MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 46 449 29 29 0
METTL17-201 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 48 95 10 10 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 27 106 8 8 0
MRPS26-201 MRPS26 Q9BYN8 Small ribosomal subunit protein mS26 chr20 Not Cancer Driver No 1 hippie, biogrid 12 102 4 4 0
MTG2-201 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 43 48 7 7 0
MTRF1L-203 MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 17 185 5 5 0
NFS1-203 NFS1 Q9Y697 Cysteine desulfurase chr20 Not Cancer Driver No 1 hippie, biogrid 29 72 9 9 1
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 hippie 40 10 2 2 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 32 49 7 7 0
PGD-201 PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 hippie, biogrid 50 19 2 2 0
PMPCB-201 PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 36 22 2 2 4
PNKD-203 PNKD Q8N490 Probable hydrolase PNKD chr2 Not Cancer Driver No 1 hippie 31 160 13 13 2
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact 31 27 6 6 0
PPP2R1A-201 PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie, biogrid 169 0 0 0 4
PPP2R1B-206 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 hippie, biogrid 45 17 1 1 0
PRKCSH-209 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 47 320 28 28 0
PSMC2-201 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 Not Cancer Driver No 1 hippie, biogrid 53 120 14 14 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 15 58 3 3 0
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SEC63-201 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 67 267 25 25 0
SLC25A3-215 SLC25A3 Q00325 Solute carrier family 25 member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 31 32 4 4 1
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 6
STRAP-202 STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 1 hippie 33 40 4 4 0
SUCLA2-218 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 38 46 5 5 3
SUCLG2-201 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 36 12 2 2 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUMO3-201 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 6 86 4 4 0
SUMO4-201 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 6 69 4 4 0
TECR-201 TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 1
TEX101-201 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 39 2 0 0 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TRMT61B-201 TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 hippie 40 124 11 11 0
TRUB2-201 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 73 6 6 0
TSFM-212 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 21 74 4 4 2
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 64 581 61 61 8
UBR5-207 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 260 1299 135 135 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UQCRC2-201 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 31 48 5 5 1
USP20-203 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie, biogrid 87 296 30 30 0
USP50-203 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 Not Cancer Driver No 1 hippie, biogrid 24 2 0 0 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 25 36 4 4 0
VDAC2-203 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 22 9 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie, biogrid 21 78 4 4 3
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0