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ADAM15-203 ,ADAM15 ,Q13444
  • Number of Interaction partner in intact: 27
  • Number of Interaction partner in biogrid: 17
  • Number of Interaction partner in hippie: 75
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 106 609 53 53 2
ADAM33-202 ADAM33 Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 81 169 23 23 0
ADAM9-209 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 biogrid 59 130 7 7 0
ARHGEF6-201 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 1 intact, hippie 106 224 28 28 0
ARHGEF7-206 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 1 hippie 67 302 30 30 0
ATXN1-202 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 intact, hippie 111 608 91 91 0
BANP-201 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie 44 315 27 27 0
BRICD5-202 BRICD5 Q6PL45 BRICHOS domain-containing protein 5 chr16 Not Cancer Driver No 1 hippie, biogrid 19 82 6 6 0
BTK-201 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 109 114 21 21 83
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 57 334 36 36 0
CLEC2B-201 CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
CX3CL1-201 CX3CL1 P78423 Fractalkine chr16 Not Cancer Driver No 1 hippie 53 259 36 36 0
DPP4-201 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 108 8 0 0 0
ECEL1-201 ECEL1 O95672 Endothelin-converting enzyme-like 1 chr2 Not Cancer Driver No 1 hippie, biogrid 95 22 2 2 4
EDN3-202 EDN3 P14138 Endothelin-3 chr20 Not Cancer Driver No 1 hippie, biogrid 51 140 36 36 3
ENST00000560629 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 92 68 6 6 27
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FHL3-201 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 intact, hippie 28 0 0 0 0
FUT8-216 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 Not Cancer Driver No 1 hippie, biogrid 55 81 17 17 1
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 64 71 11 11 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 3 intact, hippie 21 10 0 0 0
HCK-202 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 3 intact, hippie 89 124 22 22 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 143 265 30 30 6
ITGA5-201 ITGA5 P08648 Integrin alpha-5 chr12 Not Cancer Driver No 1 intact, hippie 89 202 21 21 0
ITGB3-201 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 92 68 5 5 28
ITK-201 ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 intact, hippie 106 43 9 9 1
ITSN1-206 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie 109 798 50 50 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 76 95 12 12 1
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 78 85 10 10 0
LYPD4-203 LYPD4 Q6UWN0 Ly6/PLAUR domain-containing protein 4 chr19 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
MAD2L1-201 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie 21 12 1 1 0
MAD2L2-207 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 2 intact, hippie 16 0 0 0 1
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 52 2 0 0 6
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
NCF1-201 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 intact, hippie 31 181 11 11 1
NCK1-207 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 intact, hippie 41 111 15 15 0
NONO-201 NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 70 349 46 46 0
NPHP1-203 NPHP1 O15259 Nephrocystin-1 chr2 Not Cancer Driver No 1 hippie 83 260 24 24 1
NUP62-201 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 Not Cancer Driver No 1 intact, hippie 55 378 39 39 1
ODAM-206 ODAM A1E959 Odontogenic ameloblast-associated protein chr4 Not Cancer Driver No 1 intact, hippie 49 140 17 17 0
OSTF1-201 OSTF1 Q92882 Osteoclast-stimulating factor 1 chr9 Not Cancer Driver No 1 intact, hippie 13 51 2 2 0
PACSIN3-201 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 Not Cancer Driver No 1 intact, hippie 44 291 29 29 0
PIK3R1-211 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 intact, hippie 122 271 50 50 2
PLD3-207 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 biogrid 51 62 6 6 0
PRG2-201 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie, biogrid 37 66 13 13 0
PTK6-202 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 31 12 0 0 0
RBPMS-204 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 Not Cancer Driver No 1 intact, hippie 14 87 7 7 0
RIMBP3-201 RIMBP3 Q9UFD9 RIMS-binding protein 3A chr22 Not Cancer Driver No 1 intact, hippie 70 972 30 30 0
SDF2L1-201 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 12 130 7 7 0
SFTPC-213 SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 1 hippie, biogrid 15 22 2 2 5
SH3D19-201 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 Not Cancer Driver No 1 hippie 55 530 30 30 0
SH3GL2-201 SH3GL2 Q99962 Endophilin-A1 chr9 Not Cancer Driver No 1 intact, hippie 58 215 36 36 0
SH3GLB1-201 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie 30 82 6 6 0
SH3PXD2A-203 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 111 802 86 86 0
SH3RF1-201 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 Not Cancer Driver No 1 intact, hippie 83 588 55 55 0
SH3RF3-201 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 Not Cancer Driver No 1 hippie 78 566 45 45 0
SNX30-201 SNX30 Q5VWJ9 Sorting nexin-30 chr9 Not Cancer Driver No 1 hippie 30 99 2 2 0
SNX33-201 SNX33 Q8WV41 Sorting nexin-33 chr15 Not Cancer Driver No 3 intact, hippie 48 205 15 15 0
SNX9-201 SNX9 Q9Y5X1 Sorting nexin-9 chr6 Not Cancer Driver No 3 intact, hippie 50 233 19 19 0
SORBS1-211 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 123 1116 101 101 0
SORBS2-201 SORBS2 O94875 Sorbin and SH3 domain-containing protein 2 chr4 Not Cancer Driver No 1 intact, hippie 122 857 98 98 0
SORBS3-201 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie 42 578 36 36 0
SP4-201 SP4 Q02446 Transcription factor Sp4 chr7 Not Cancer Driver No 1 intact, hippie 65 532 47 47 0
SPAG5-201 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 Not Cancer Driver No 1 intact, hippie 95 636 59 59 0
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 40 130 10 10 1
ST8SIA5-201 ST8SIA5 O15466 Alpha-2,8-sialyltransferase 8E chr18 Not Cancer Driver No 1 hippie, biogrid 74 0 0 0 0
TEC-201 TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 66 57 11 11 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TMPRSS11B-201 TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 77 5 0 0 0
TMPRSS2-201 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 47 25 3 3 0
TMPRSS4-201 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 41 34 1 1 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIP13-201 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 intact, hippie 49 30 5 5 1
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 48 63 9 9 0