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ADAMTS4-202 ,ADAMTS4 ,O75173
  • Number of Interaction partner in intact: 17
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 67
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAN-202 ACAN P16112 Aggrecan core protein chr15 Not Cancer Driver No 1 hippie 243 1891 218 218 2
ADAM21-201 ADAM21 Q9UKJ8 Disintegrin and metalloproteinase domain-containing protein 21 chr14 Not Cancer Driver No 1 hippie, biogrid 117 4 0 0 0
ADAMTS15-201 ADAMTS15 Q8TE58 A disintegrin and metalloproteinase with thrombospondin motifs 15 chr11 Not Cancer Driver No 1 biogrid 100 141 17 17 0
ADAMTS2-201 ADAMTS2 O95450 A disintegrin and metalloproteinase with thrombospondin motifs 2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 237 306 67 67 0
ADAMTS4-202 ADAMTS4 O75173 A disintegrin and metalloproteinase with thrombospondin motifs 4 chr1 Not Cancer Driver No 1 hippie 102 160 19 19 0
ADAMTS8-201 ADAMTS8 Q9UP79 A disintegrin and metalloproteinase with thrombospondin motifs 8 chr11 Not Cancer Driver No 1 biogrid 89 207 15 15 0
ATP2B2-202 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 206 362 68 68 0
BCAN-201 BCAN Q96GW7 Brevican core protein chr1 Not Cancer Driver No 1 hippie 167 342 69 69 0
BIRC2-201 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 49 85 7 7 0
BIRC6-201 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 Census, Compendium Yes 2 intact, hippie, biogrid 468 1314 124 124 0
BMP8B-201 BMP8B P34820 Bone morphogenetic protein 8B chr1 Not Cancer Driver No 1 hippie, biogrid 18 93 4 4 0
CCDC33-212 CCDC33 Q8N5R6 Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 2 hippie, biogrid 100 621 57 57 0
CERCAM-201 CERCAM Q5T4B2 Inactive glycosyltransferase 25 family member 3 chr9 Not Cancer Driver No 1 hippie, biogrid 64 69 11 11 0
CHRNA5-201 CHRNA5 P30532 Neuronal acetylcholine receptor subunit alpha-5 chr15 Not Cancer Driver No 1 hippie, biogrid 41 25 4 4 0
DICER1-201 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 2 intact, hippie, biogrid 183 363 31 31 4
DPH6-201 DPH6 Q7L8W6 Diphthine--ammonia ligase chr15 Not Cancer Driver No 2 intact, hippie, biogrid 23 0 0 0 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
FEZ2-204 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 Not Cancer Driver No 1 hippie, biogrid 11 248 6 6 0
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 289 1249 137 137 8
FRAS1-206 FRAS1 Q86XX4 Extracellular matrix organizing protein FRAS1 chr4 Not Cancer Driver No 2 hippie, biogrid 475 774 99 99 0
FURIN-201 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie 72 283 30 30 0
FUT11-201 FUT11 Q495W5 Alpha-(1,3)-fucosyltransferase 11 chr10 Not Cancer Driver No 1 hippie, biogrid 23 101 8 8 0
GANAB-202 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie, biogrid 91 133 17 17 3
GUSB-201 GUSB P08236 Beta-glucuronidase chr7 Not Cancer Driver No 1 hippie, biogrid 71 11 0 0 34
HMGCLL1-205 HMGCLL1 Q8TB92 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic chr6 Not Cancer Driver No 1 hippie, biogrid 93 2 2 2 0
HP-201 HP P00738 Haptoglobin chr16 Not Cancer Driver No 1 hippie 34 57 2 2 1
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 49 282 26 26 0
IDS-201 IDS P22304 Iduronate 2-sulfatase chrX Not Cancer Driver No 1 hippie, biogrid 74 86 11 11 91
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie, biogrid 143 265 30 30 6
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie, biogrid 139 282 37 37 63
ITPA-201 ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 Not Cancer Driver No 2 intact, hippie, biogrid 13 10 1 1 1
KIAA0232-201 KIAA0232 Q92628 Uncharacterized protein KIAA0232 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 115 654 60 60 0
LGMN-201 LGMN Q99538 Legumain chr14 Not Cancer Driver No 1 hippie, biogrid 40 112 11 11 0
LOXL2-201 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 103 39 3 3 0
LRP5-201 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 Not Cancer Driver No 1 hippie, biogrid 196 189 24 24 54
LRP6-201 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 Not Cancer Driver No 1 hippie, biogrid 148 255 27 27 5
MANBA-216 MANBA O00462 Beta-mannosidase chr4 Not Cancer Driver No 2 hippie, biogrid 81 10 0 0 3
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 59 153 18 18 2
MT2A-201 MT2A P02795 Metallothionein-2 chr16 Not Cancer Driver No 1 hippie 7 0 0 0 0
NSUN3-201 NSUN3 Q9H649 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
OLFM2-201 OLFM2 O95897 Noelin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 60 16 0 0 0
OS9-202 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 1 hippie, biogrid 62 451 43 43 0
P3H3-201 P3H3 Q8IVL6 Prolyl 3-hydroxylase 3 chr12 Not Cancer Driver No 1 hippie 59 311 30 30 0
P3H4-202 P3H4 Q92791 Endoplasmic reticulum protein SC65 chr17 Not Cancer Driver No 1 hippie, biogrid 33 82 5 5 0
PCSK9-201 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 Not Cancer Driver No 1 hippie, biogrid 73 150 20 20 8
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 61 147 18 18 0
PRKAG3-202 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 Not Cancer Driver No 1 hippie 55 141 16 16 0
RAD51B-209 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 Census Yes 2 hippie, biogrid 32 12 0 0 0
RAD51C-201 RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 Not Cancer Driver No 1 hippie, biogrid 39 18 2 2 6
RCN2-203 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 27 125 7 7 0
SCPEP1-201 SCPEP1 Q9HB40 Retinoid-inducible serine carboxypeptidase chr17 Not Cancer Driver No 1 hippie, biogrid 35 1 0 0 0
SERPINA1-202 SERPINA1 P01009 Alpha-1-antitrypsin chr14 Not Cancer Driver No 1 hippie 51 38 7 7 0
SERPINA3-201 SERPINA3 P01011 Alpha-1-antichymotrypsin chr14 Not Cancer Driver No 1 hippie 94 19 9 9 0
SIL1-202 SIL1 Q9H173 Nucleotide exchange factor SIL1 chr5 Not Cancer Driver No 1 hippie, biogrid 32 126 10 10 0
SRPX2-201 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX Not Cancer Driver No 1 hippie 59 64 12 12 0
TARBP2-201 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 34 203 18 18 0
TFAP4-201 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 2 intact, hippie, biogrid 49 287 41 41 0
TOR3A-203 TOR3A Q9H497 Torsin-3A chr1 Not Cancer Driver No 1 hippie, biogrid 38 16 0 0 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 51 4 1 1 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 2 intact, hippie, biogrid 45 52 6 6 6
TUBA1C-201 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 hippie, biogrid 26 50 2 2 0
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 intact, hippie, biogrid 50 39 2 2 4
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 29 63 5 5 5
TUBB1-201 TUBB1 Q9H4B7 Tubulin beta-1 chain chr20 Not Cancer Driver No 2 intact, hippie, biogrid 52 38 5 5 1
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 2 intact, hippie, biogrid 51 54 6 6 10
UGGT2-203 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 Not Cancer Driver No 1 hippie, biogrid 136 65 5 5 0
XIAP-202 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 2 hippie, biogrid 61 55 2 2 0
YTHDC1-201 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 intact, hippie 52 597 36 36 0
ZBTB16-201 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 Census, Compendium Yes 1 hippie 105 268 42 42 1