Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AHSA1-201 | AHSA1 | O95433 | Activator of 90 kDa heat shock protein ATPase homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 147 | 14 | 14 | 0 |
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 23 | 104 | 9 | 9 | 0 |
| APPL1-201 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | Not Cancer Driver | No | 1 | hippie | 35 | 293 | 18 | 18 | 1 |
| ARIH2-201 | ARIH2 | O95376 | E3 ubiquitin-protein ligase ARIH2 | chr3 | Not Cancer Driver | No | 1 | hippie | 45 | 85 | 9 | 9 | 0 |
| ASB15-205 | ASB15 | Q8WXK1 | Ankyrin repeat and SOCS box protein 15 | chr7 | Not Cancer Driver | No | 1 | hippie | 83 | 32 | 5 | 5 | 0 |
| ASB3-201 | ASB3 | Q9Y575 | Ankyrin repeat and SOCS box protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 54 | 0 | 0 | 0 | 0 |
| ASPSCR1-202 | ASPSCR1 | Q9BZE9 | Tether containing UBX domain for GLUT4 | chr17 | Census | Yes | 1 | hippie, biogrid | 18 | 298 | 11 | 11 | 0 |
| AURKB-214 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 63 | 4 | 4 | 0 |
| BCAT1-201 | BCAT1 | P54687 | Branched-chain-amino-acid aminotransferase, cytosolic | chr12 | Not Cancer Driver | No | 1 | hippie | 53 | 8 | 2 | 2 | 0 |
| BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 167 | 1466 | 127 | 127 | 34 |
| CAT-201 | CAT | P04040 | Catalase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 178 | 11 | 11 | 0 |
| CBX1-201 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 155 | 14 | 14 | 0 |
| CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 38 | 5 | 0 | 0 | 0 |
| CFTR-201 | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | intact | 216 | 145 | 9 | 9 | 130 |
| COPS5-201 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 27 | 32 | 4 | 4 | 0 |
| CUL1-201 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 127 | 65 | 9 | 9 | 0 |
| CUL2-203 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 64 | 66 | 2 | 2 | 0 |
| CUL3-201 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 98 | 168 | 18 | 18 | 3 |
| CUL4B-231 | CUL4B | Q13620 | Cullin-4B | chrX | Not Cancer Driver | No | 1 | intact, hippie | 83 | 207 | 23 | 23 | 2 |
| CUL5-201 | CUL5 | Q93034 | Cullin-5 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 69 | 5 | 1 | 1 | 0 |
| DCUN1D1-201 | DCUN1D1 | Q96GG9 | DCN1-like protein 1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 13 | 1 | 1 | 0 |
| DERA-201 | DERA | Q9Y315 | Deoxyribose-phosphate aldolase | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 2 | 0 | 0 | 0 |
| EMC1-207 | EMC1 | Q8N766 | ER membrane protein complex subunit 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 61 | 4 | 4 | 2 |
| EMC2-201 | EMC2 | Q15006 | ER membrane protein complex subunit 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 38 | 29 | 2 | 2 | 0 |
| ENST00000635511 | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 0 | 0 | 0 | 0 | 0 |
| FASTK-201 | FASTK | Q14296 | Fas-activated serine/threonine kinase | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 56 | 143 | 13 | 13 | 0 |
| FBXO32-203 | FBXO32 | Q969P5 | F-box only protein 32 | chr8 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 1 |
| FKBP1A-204 | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 39 | 6 | 6 | 0 |
| FKBP1B-201 | FKBP1B | P68106 | Peptidyl-prolyl cis-trans isomerase FKBP1B | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 60 | 4 | 4 | 0 |
| FOXA2-201 | FOXA2 | Q9Y261 | Hepatocyte nuclear factor 3-beta | chr20 | Compendium | Yes | 1 | intact, hippie | 60 | 260 | 29 | 29 | 0 |
| GABARAPL1-201 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 10 | 10 | 1 | 1 | 0 |
| GABARAPL2-201 | GABARAPL2 | P60520 | Gamma-aminobutyric acid receptor-associated protein-like 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 4 | 2 | 1 | 1 | 0 |
| GCK-204 | GCK | P35557 | Hexokinase-4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 73 | 12 | 12 | 98 |
| GCLC-214 | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 167 | 15 | 15 | 3 |
| GLO1-201 | GLO1 | Q04760 | Lactoylglutathione lyase | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 46 | 5 | 5 | 0 |
| GRHPR-201 | GRHPR | Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 36 | 3 | 3 | 0 |
| GYG2-204 | GYG2 | O15488 | Glycogenin-2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 219 | 19 | 19 | 0 |
| HEXIM1-201 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 354 | 35 | 35 | 0 |
| KHK-201 | KHK | P50053 | Ketohexokinase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 42 | 4 | 4 | 2 |
| LARP7-201 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 39 | 353 | 28 | 28 | 0 |
| LGR4-201 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 73 | 16 | 2 | 2 | 0 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact | 402 | 91 | 13 | 13 | 20 |
| MAN2B1-203 | MAN2B1 | O00754 | Lysosomal alpha-mannosidase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 146 | 15 | 15 | 37 |
| MAP3K6-201 | MAP3K6 | O95382 | Mitogen-activated protein kinase kinase kinase 6 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 72 | 392 | 21 | 21 | 0 |
| MARK3-205 | MARK3 | P27448 | MAP/microtubule affinity-regulating kinase 3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 376 | 38 | 38 | 1 |
| MCFD2-201 | MCFD2 | Q8NI22 | Multiple coagulation factor deficiency protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 90 | 9 | 9 | 4 |
| MEPCE-201 | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie | 46 | 449 | 29 | 29 | 0 |
| MMGT1-201 | MMGT1 | Q8N4V1 | ER membrane protein complex subunit 5 | chrX | Not Cancer Driver | No | 1 | hippie | 15 | 17 | 4 | 4 | 0 |
| MOV10-203 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 90 | 103 | 6 | 6 | 0 |
| NAXD-208 | NAXD | Q8IW45 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | chr13 | Not Cancer Driver | No | 1 | hippie | 25 | 25 | 0 | 0 | 2 |
| NHLRC1-201 | NHLRC1 | Q6VVB1 | E3 ubiquitin-protein ligase NHLRC1 | chr6 | Not Cancer Driver | No | 1 | hippie | 52 | 18 | 3 | 3 | 22 |
| NTRK1-206 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 133 | 57 | 8 | 8 | 23 |
| NXF1-201 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 85 | 163 | 28 | 28 | 0 |
| PCLAF-201 | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 15 | 112 | 16 | 16 | 0 |
| PHKG2-204 | PHKG2 | P15735 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 50 | 4 | 4 | 4 |
| PIH1D1-201 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 24 | 160 | 13 | 13 | 0 |
| PKM-202 | PKM | P14618 | Pyruvate kinase PKM | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 58 | 11 | 11 | 0 |
| PRKAA2-201 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 90 | 98 | 18 | 18 | 0 |
| PRKAB1-201 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 21 | 125 | 11 | 11 | 0 |
| PRKAB2-201 | PRKAB2 | O43741 | 5'-AMP-activated protein kinase subunit beta-2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 111 | 8 | 8 | 0 |
| PRKAG1-206 | PRKAG1 | P54619 | 5'-AMP-activated protein kinase subunit gamma-1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 27 | 25 | 2 | 2 | 0 |
| PRNP-201 | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 28 | 117 | 8 | 8 | 19 |
| PSMB6-201 | PSMB6 | P28072 | Proteasome subunit beta type-6 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 22 | 1 | 1 | 0 |
| PUS1-202 | PUS1 | Q9Y606 | Pseudouridylate synthase 1 homolog | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 157 | 10 | 10 | 1 |
| PYGB-201 | PYGB | P11216 | Glycogen phosphorylase, brain form | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 29 | 5 | 5 | 0 |
| RAN-212 | RAN | P62826 | GTP-binding nuclear protein Ran | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 14 | 0 | 0 | 0 |
| RASSF5-202 | RASSF5 | Q8WWW0 | Ras association domain-containing protein 5 | chr1 | Not Cancer Driver | No | 1 | hippie | 25 | 184 | 11 | 11 | 0 |
| RNF123-201 | RNF123 | Q5XPI4 | E3 ubiquitin-protein ligase RNF123 | chr3 | Not Cancer Driver | No | 1 | hippie | 126 | 220 | 23 | 23 | 0 |
| RNF126-201 | RNF126 | Q9BV68 | E3 ubiquitin-protein ligase RNF126 | chr19 | Not Cancer Driver | No | 1 | hippie | 28 | 184 | 19 | 19 | 0 |
| SDHB-201 | SDHB | P21912 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | chr1 | Census | Yes | 1 | hippie, biogrid | 30 | 17 | 1 | 1 | 21 |
| SERPINE2-201 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | Not Cancer Driver | No | 1 | hippie | 55 | 0 | 0 | 0 | 0 |
| SH3GLB1-201 | SH3GLB1 | Q9Y371 | Endophilin-B1 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 82 | 6 | 6 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | intact, hippie | 80 | 113 | 15 | 15 | 5 |
| SP100-201 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | Not Cancer Driver | No | 1 | hippie | 76 | 683 | 61 | 61 | 0 |
| SPATA20-202 | SPATA20 | Q8TB22 | Spermatogenesis-associated protein 20 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 164 | 16 | 16 | 0 |
| STBD1-201 | STBD1 | O95210 | Starch-binding domain-containing protein 1 | chr4 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 39 | 230 | 27 | 27 | 0 |
| SULT1E1-201 | SULT1E1 | P49888 | Sulfotransferase 1E1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 15 | 4 | 4 | 0 |
| TKFC-201 | TKFC | Q3LXA3 | Triokinase/FMN cyclase | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 93 | 9 | 9 | 2 |
| TNS2-201 | TNS2 | Q63HR2 | Tensin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 97 | 800 | 47 | 47 | 0 |
| TOM1L2-202 | TOM1L2 | Q6ZVM7 | TOM1-like protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 335 | 23 | 23 | 0 |
| TRIM28-201 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 67 | 431 | 32 | 32 | 0 |
| UBE2M-201 | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 25 | 32 | 4 | 4 | 0 |
| USP5-201 | USP5 | P45974 | Ubiquitin carboxyl-terminal hydrolase 5 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 263 | 33 | 33 | 0 |
| UVRAG-201 | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 58 | 243 | 21 | 21 | 0 |
| VIRMA-201 | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 157 | 634 | 73 | 73 | 0 |
| VPS25-201 | VPS25 | Q9BRG1 | Vacuolar protein-sorting-associated protein 25 | chr17 | Not Cancer Driver | No | 1 | hippie | 12 | 10 | 0 | 0 | 0 |
| YTHDF2-201 | YTHDF2 | Q9Y5A9 | YTH domain-containing family protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 376 | 29 | 29 | 0 |
| ZDHHC5-201 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 66 | 463 | 46 | 46 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|