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AGO3-203 ,AGO3 ,Q9H9G7
  • Number of Interaction partner in intact: 54
  • Number of Interaction partner in biogrid: 18
  • Number of Interaction partner in hippie: 131
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 96 43 5 5 4
AGO1-201 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 2 hippie, biogrid 94 87 10 10 1
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 2 intact, hippie 91 142 12 12 10
AGO3-203 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 1 hippie 93 143 18 18 0
AGO4-201 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 83 183 22 22 0
ANKMY2-201 ANKMY2 Q8IV38 Ankyrin repeat and MYND domain-containing protein 2 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 38 99 11 11 0
ANKRD17-202 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie 221 1791 155 155 9
AP3B1-201 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 3 hippie, biogrid 91 317 22 22 1
AP3D1-201 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 109 407 52 52 0
AP3M1-201 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 3 hippie, biogrid 33 19 1 1 0
AP3S1-201 AP3S1 Q92572 AP-3 complex subunit sigma-1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 20 0 0 0 0
ATAD3B-206 ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie 63 245 17 17 0
ATOH1-201 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 54 329 46 46 0
ATP4B-201 ATP4B P51164 Potassium-transporting ATPase subunit beta chr13 Not Cancer Driver No 1 intact, hippie 30 2 0 0 0
ATP6V0D2-201 ATP6V0D2 Q8N8Y2 V-type proton ATPase subunit d 2 chr8 Not Cancer Driver No 1 intact, hippie 63 0 0 0 0
ATXN2-218 ATXN2 Q99700 Ataxin-2 chr12 Not Cancer Driver No 1 hippie 114 1225 104 104 0
BAG5-201 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 intact, hippie 27 63 5 5 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BDNF-202 BDNF P23560 Brain-derived neurotrophic factor chr11 Not Cancer Driver No 1 hippie 33 80 12 12 0
BICD1-210 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 105 661 70 70 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
CAND1-208 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 118 88 6 6 0
CCT3-201 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact, hippie 53 95 11 11 0
CELF1-202 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 Not Cancer Driver No 1 hippie 50 166 14 14 0
CEP85-201 CEP85 Q6P2H3 Centrosomal protein of 85 kDa chr1 Not Cancer Driver No 1 hippie 59 611 47 47 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CIR1-201 CIR1 Q86X95 Corepressor interacting with RBPJ 1 chr2 Not Cancer Driver No 1 hippie 14 385 9 9 0
CLNS1A-204 CLNS1A P54105 Methylosome subunit pICln chr11 Not Cancer Driver No 1 hippie 12 170 9 9 0
CNOT2-201 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 1 hippie 56 354 46 46 0
CNOT6L-201 CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie 43 37 2 2 0
CNOT7-201 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 2 intact, hippie 20 21 0 0 0
CNOT9-201 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 32 30 0 0 0
CPEB1-219 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 64 221 26 26 0
CPEB4-201 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 Not Cancer Driver No 1 hippie 65 444 39 39 0
CTIF-201 CTIF O43310 CBP80/20-dependent translation initiation factor chr18 Not Cancer Driver No 1 hippie 74 385 46 46 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 98 168 18 18 3
CUL5-201 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 69 5 1 1 0
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
DAZL-202 DAZL Q92904 Deleted in azoospermia-like chr3 Not Cancer Driver No 1 hippie 23 129 11 11 0
DBT-202 DBT P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 49 82 7 7 3
DCP1A-206 DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 hippie 38 385 27 27 0
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 intact, hippie 20 13 3 3 1
DDX6-206 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 hippie 29 129 6 6 4
DICER1-201 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 2 intact, hippie 183 363 31 31 4
DNAJA1-201 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 29 154 13 13 0
ECH1-201 ECH1 Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 28 23 2 2 0
ECI2-202 ECI2 O75521 Enoyl-CoA delta isomerase 2 chr6 Not Cancer Driver No 1 intact, hippie 44 70 5 5 0
EDC4-201 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie 109 702 56 56 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie 98 100 10 10 0
EIF3L-215 EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 intact, hippie 45 41 1 1 0
EIF4B-201 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 intact, hippie 80 588 76 76 0
EIF4ENIF1-201 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie 86 902 75 75 0
FAM120C-202 FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 127 511 66 66 0
FBXO7-201 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie, biogrid 49 243 24 24 1
FKBP5-201 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 47 150 15 15 0
FLNA-202 FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 314 1460 162 162 29
FUBP3-201 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 49 354 38 38 0
FXR2-201 FXR2 P51116 RNA-binding protein FXR2 chr17 Not Cancer Driver No 1 hippie 45 388 29 29 0
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 55 352 38 38 0
HELZ-201 HELZ P42694 Probable helicase with zinc finger domain chr17 Not Cancer Driver No 1 hippie 123 870 30 30 0
HNRNPD-201 HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 28 206 12 12 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 5 intact, hippie, biogrid 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 2 intact, hippie 70 255 29 29 0
HSPA9-201 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 47 284 19 19 2
IPO8-201 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 1 intact, hippie 93 111 10 10 3
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
LIMD1-201 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 47 430 29 29 0
LONRF3-202 LONRF3 Q496Y0 LON peptidase N-terminal domain and RING finger protein 3 chrX Not Cancer Driver No 3 intact, hippie, biogrid 82 264 33 33 0
LSM14A-201 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 1 hippie 51 408 47 47 0
LZTS2-205 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 63 511 51 51 0
MAP1LC3A-201 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 19 24 1 1 0
MARK1-201 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 Not Cancer Driver No 1 biogrid 129 454 81 81 0
MARK2-204 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 biogrid 84 445 52 52 0
MARK3-205 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 biogrid 64 376 38 38 1
MEX3B-201 MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 57 439 45 45 0
MKRN2-201 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 30 145 7 7 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
MYH9-201 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 247 1124 126 126 13
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 193 891 140 140 0
OTUD4-201 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 94 789 74 74 0
PABPC1-201 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie 53 317 32 32 0
PATL1-201 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 51 500 31 31 0
PHB2-203 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie 25 26 4 4 0
PHIP-201 PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie 152 838 74 74 0
PPP5C-201 PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 2 intact, hippie 58 73 10 10 0
PRKAR1A-216 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 hippie 26 66 5 5 15
PRMT5-202 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie 62 72 3 3 0
PRPF31-201 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 37 213 9 9 2
PRRC2A-202 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie 111 2119 107 107 0
PSPC1-201 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 intact, hippie 73 368 61 61 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 8 52 2 2 0
PUM1-201 PUM1 Q14671 Pumilio homolog 1 chr1 Not Cancer Driver No 1 hippie 107 640 50 50 3
QPCTL-201 QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 Not Cancer Driver No 1 hippie 32 22 0 0 0
R3HDM2-202 R3HDM2 Q9Y2K5 R3H domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 60 839 53 53 0
RANGRF-201 RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 Not Cancer Driver No 2 hippie, biogrid 6 42 3 3 0
RBM10-203 RBM10 P98175 RNA-binding protein 10 chrX Census, Compendium Yes 1 hippie 86 777 72 72 0
RBMS1-201 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 38 244 27 27 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RUVBL2-206 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie 52 100 11 11 0
SF3B6-201 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 intact, hippie 7 10 0 0 0
SLC22A2-202 SLC22A2 O15244 Solute carrier family 22 member 2 chr6 Not Cancer Driver No 1 intact, hippie 94 32 10 10 0
SLC25A3-215 SLC25A3 Q00325 Solute carrier family 25 member 3 chr12 Not Cancer Driver No 1 intact, hippie 31 32 4 4 1
SPIN1-201 SPIN1 Q9Y657 Spindlin-1 chr9 Not Cancer Driver No 1 hippie 19 133 14 14 0
SPSB4-201 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 35 75 1 1 0
SPTAN1-202 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 intact, hippie 236 983 84 84 0
SPTBN1-202 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 intact, hippie 218 877 86 86 16
STK38-201 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 Not Cancer Driver No 1 hippie 36 78 4 4 0
SUN2-218 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie 49 214 13 13 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact, hippie 62 233 23 23 0
TARBP2-201 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 Not Cancer Driver No 1 hippie 34 203 18 18 0
THBS1-201 THBS1 P07996 Thrombospondin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 153 321 50 50 0
TNRC6A-202 TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 4 intact, hippie 203 1830 191 191 0
TNRC6B-206 TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 4 intact, hippie 149 1735 140 140 0
TNRC6C-203 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 Not Cancer Driver No 1 intact, hippie 0 0 0 0 0
TOMM20-201 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 6 25 0 0 0
TRIM21-201 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 intact, hippie 63 49 8 8 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 45 52 6 6 6
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 29 63 5 5 5
TUBB2A-201 TUBB2A Q13885 Tubulin beta-2A chain chr6 Not Cancer Driver No 1 intact, hippie 32 70 5 5 2
TUBB4A-201 TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 intact, hippie 65 61 5 5 2
TUBB4B-201 TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 intact, hippie 43 65 7 7 1
UBAP2L-207 UBAP2L Q14157 Ubiquitin-associated protein 2-like chr1 Not Cancer Driver No 1 hippie 66 1040 66 66 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WDR77-201 WDR77 Q9BQA1 Methylosome protein WDR77 chr1 Not Cancer Driver No 1 intact, hippie 25 42 2 2 0
WTIP-202 WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 Not Cancer Driver No 1 intact, hippie 24 219 0 0 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
YTHDF1-202 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 Not Cancer Driver No 1 hippie 67 371 31 31 0
YTHDF2-201 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie 48 376 29 29 0
YTHDF3-205 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 hippie 57 409 39 39 0
ZC3H7A-201 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 63 225 17 17 0
ZC3HAV1-201 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie 95 345 42 42 0
ZFP36-203 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 hippie 30 263 24 24 0
ZNF346-201 ZNF346 Q9UL40 Zinc finger protein 346 chr5 Not Cancer Driver No 1 hippie 17 175 11 11 0