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AGO4-201 ,AGO4 ,Q9HCK5
  • Number of Interaction partner in intact: 68
  • Number of Interaction partner in biogrid: 41
  • Number of Interaction partner in hippie: 119
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 96 43 5 5 4
AGK-218 AGK Q53H12 Acylglycerol kinase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 41 77 6 6 0
AGO2-201 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact, hippie 91 142 12 12 10
AGO3-203 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 93 143 18 18 0
AGO4-201 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 1 hippie 83 183 22 22 0
ANKMY2-201 ANKMY2 Q8IV38 Ankyrin repeat and MYND domain-containing protein 2 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 38 99 11 11 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARF4-201 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 intact, hippie 7 0 0 0 0
ATP5F1C-202 ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 27 11 0 0 0
ATP5ME-201 ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie 4 18 1 1 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BCR-201 BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie, biogrid 112 607 57 57 0
CCT5-201 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 intact, hippie 65 72 8 8 1
CDIPT-201 CDIPT O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase chr16 Not Cancer Driver No 1 intact, hippie 18 0 0 0 0
CTNNA3-203 CTNNA3 Q9UI47 Catenin alpha-3 chr10 Not Cancer Driver No 1 hippie, biogrid 225 187 37 37 1
CTR9-201 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 109 385 29 29 0
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 141 373 31 31 3
CUL9-201 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie, biogrid 239 633 59 59 0
DBT-202 DBT P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 49 82 7 7 3
DDX6-206 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 hippie, biogrid 29 129 6 6 4
DICER1-201 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 2 hippie, biogrid 183 363 31 31 4
DNAJA1-201 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 29 154 13 13 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 intact, hippie 34 174 18 18 0
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie 41 141 19 19 2
ECD-201 ECD O95905 Protein ecdysoneless homolog chr10 Not Cancer Driver No 1 hippie, biogrid 44 257 15 15 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie 98 100 10 10 0
EEF1G-201 EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 36 67 6 6 0
EIF4B-201 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 intact, hippie 80 588 76 76 0
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie 29 160 18 18 3
ENST00000621281 MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 6 38 2 2 0
FKBP5-201 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 hippie, biogrid 47 150 15 15 0
GALK1-205 GALK1 P51570 Galactokinase chr17 Not Cancer Driver No 1 intact, hippie 23 45 5 5 11
HNRNPC-202 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 intact, hippie 27 228 22 22 0
HSD17B14-201 HSD17B14 Q9BPX1 17-beta-hydroxysteroid dehydrogenase 14 chr19 Not Cancer Driver No 1 hippie, biogrid 26 42 7 7 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact, hippie 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 70 255 29 29 0
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 intact, hippie 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 intact, hippie 19 200 7 7 0
HSPA5-201 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 intact, hippie 49 282 26 26 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 82 252 28 28 0
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 45 83 1 1 2
HTATSF1-201 HTATSF1 O43719 HIV Tat-specific factor 1 chrX Not Cancer Driver No 1 hippie, biogrid 78 575 57 57 0
IGF2BP1-201 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 Not Cancer Driver No 1 hippie 118 298 71 71 0
IGFBP6-201 IGFBP6 P24592 Insulin-like growth factor-binding protein 6 chr12 Not Cancer Driver No 1 hippie, biogrid 13 166 11 11 0
IPO8-201 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 1 intact, hippie 93 111 10 10 3
JAK1-201 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 Census, Compendium Yes 1 intact, hippie 109 120 6 6 2
KBTBD8-201 KBTBD8 Q8NFY9 Kelch repeat and BTB domain-containing protein 8 chr3 Not Cancer Driver No 1 hippie, biogrid 64 32 3 3 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
LEO1-201 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 hippie, biogrid 57 611 53 53 0
LEPR-202 LEPR P48357 Leptin receptor chr1 Not Cancer Driver No 1 hippie, biogrid 178 57 10 10 0
LIMD1-201 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 47 430 29 29 0
MARK1-201 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 Not Cancer Driver No 1 biogrid 129 454 81 81 0
MARK2-204 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 biogrid 84 445 52 52 0
MARK3-205 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 biogrid 64 376 38 38 1
MEX3B-201 MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 57 439 45 45 0
MYCBP-201 MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 6 55 4 4 0
NUDCD1-201 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 49 38 2 2 0
PABPC1-201 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 intact, hippie 53 317 32 32 0
PABPC4-202 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 intact, hippie 68 255 40 40 0
PAF1-201 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 36 378 23 23 0
PCSK1N-201 PCSK1N Q9UHG2 ProSAAS chrX Not Cancer Driver No 1 hippie, biogrid 3 187 3 3 0
PGAM5-203 PGAM5 Q96HS1 Serine/threonine-protein phosphatase PGAM5, mitochondrial chr12 Not Cancer Driver No 1 hippie 23 103 7 7 0
PITRM1-201 PITRM1 Q5JRX3 Presequence protease, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 70 222 16 16 2
PPME1-201 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 28 146 8 8 0
PRDX1-202 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 intact, hippie 23 40 7 7 0
PRMT5-202 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie 62 72 3 3 0
PRPF40B-209 PRPF40B Q6NWY9 Pre-mRNA-processing factor 40 homolog B chr12 Census Yes 1 hippie, biogrid 68 651 53 53 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 2 hippie, biogrid 8 52 2 2 0
PTS-201 PTS Q03393 6-pyruvoyl tetrahydrobiopterin synthase chr11 Not Cancer Driver No 1 intact, hippie 6 22 0 0 21
QPCTL-201 QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 Not Cancer Driver No 1 hippie 32 22 0 0 0
RASSF8-218 RASSF8 Q8NHQ8 Ras association domain-containing protein 8 chr12 Not Cancer Driver No 1 hippie, biogrid 35 207 14 14 0
RBM10-203 RBM10 P98175 RNA-binding protein 10 chrX Census, Compendium Yes 1 hippie 86 777 72 72 0
RPL11-206 RPL11 P62913 Large ribosomal subunit protein uL5 chr1 Not Cancer Driver No 1 intact, hippie 19 12 1 1 1
RPL12-201 RPL12 P30050 Large ribosomal subunit protein uL11 chr9 Not Cancer Driver No 1 intact, hippie 9 75 3 3 0
RPL23-206 RPL23 P62829 Large ribosomal subunit protein uL14 chr17 Not Cancer Driver No 1 intact, hippie 11 29 2 2 0
RPL24-201 RPL24 P83731 Large ribosomal subunit protein eL24 chr3 Not Cancer Driver No 1 intact, hippie 14 105 11 11 0
RPL27-201 RPL27 P61353 Large ribosomal subunit protein eL27 chr17 Not Cancer Driver No 1 intact, hippie 18 13 3 3 0
RPL27A-201 RPL27A P46776 Large ribosomal subunit protein uL15 chr11 Not Cancer Driver No 1 intact, hippie 5 56 2 2 0
RPL35-201 RPL35 P42766 Large ribosomal subunit protein uL29 chr9 Not Cancer Driver No 1 intact, hippie 9 65 6 6 0
RPL38-201 RPL38 P63173 Large ribosomal subunit protein eL38 chr17 Not Cancer Driver No 1 intact, hippie 2 9 0 0 0
RPL8-207 RPL8 P62917 Large ribosomal subunit protein uL2 chr8 Not Cancer Driver No 1 intact, hippie 23 116 17 17 0
RPS12-201 RPS12 P25398 Small ribosomal subunit protein eS12 chr6 Not Cancer Driver No 1 intact, hippie 13 0 0 0 0
RPS18-230 RPS18 P62269 Small ribosomal subunit protein uS13 chr6 Not Cancer Driver No 1 intact, hippie 11 27 2 2 0
RPS25-202 RPS25 P62851 Small ribosomal subunit protein eS25 chr11 Not Cancer Driver No 1 intact, hippie 12 60 7 7 0
RPS26-204 RPS26 P62854 Small ribosomal subunit protein eS26 chr12 Not Cancer Driver No 1 intact, hippie 7 52 3 3 2
RPS3A-201 RPS3A P61247 Small ribosomal subunit protein eS1 chr4 Compendium Yes 1 intact, hippie 15 85 3 3 0
RPS5-201 RPS5 P46782 Small ribosomal subunit protein uS7 chr19 Not Cancer Driver No 1 intact, hippie 31 41 5 5 0
RPS9-201 RPS9 P46781 Small ribosomal subunit protein uS4 chr19 Not Cancer Driver No 1 intact, hippie 14 34 3 3 0
SART3-206 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 31 31 0
SF3B2-201 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 hippie, biogrid 84 804 80 80 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie, biogrid 43 435 19 19 0
SLC25A1-201 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie 17 34 1 1 15
SLC25A10-202 SLC25A10 Q9UBX3 Mitochondrial dicarboxylate carrier chr17 Not Cancer Driver No 1 hippie 23 0 0 0 0
SLC25A13-201 SLC25A13 Q9UJS0 Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 73 23 2 2 1
SLC25A22-228 SLC25A22 Q9H936 Mitochondrial glutamate carrier 1 chr11 Not Cancer Driver No 1 hippie 27 22 3 3 1
SLC25A3-215 SLC25A3 Q00325 Solute carrier family 25 member 3 chr12 Not Cancer Driver No 1 intact, hippie 31 32 4 4 1
SLC25A5-201 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 26 0 0 0 0
SNRPD2-201 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 intact, hippie 16 67 8 8 0
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 20 0 0 0 6
STAMBP-202 STAMBP O95630 STAM-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 42 143 15 15 6
SUCLA2-218 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 Not Cancer Driver No 1 intact, hippie 38 46 5 5 3
TARBP2-201 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 Not Cancer Driver No 1 hippie, biogrid 34 203 18 18 0
TBX20-201 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 Not Cancer Driver No 1 hippie, biogrid 95 201 43 43 2
TNRC6A-202 TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 4 intact, hippie, biogrid 203 1830 191 191 0
TNRC6B-206 TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 2 intact, hippie 149 1735 140 140 0
TNRC6C-203 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 Not Cancer Driver No 2 intact, hippie, biogrid 0 0 0 0 0
TRIM21-201 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 intact, hippie 63 49 8 8 0
TRIM41-201 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 Not Cancer Driver No 1 hippie, biogrid 44 388 19 19 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 45 52 6 6 6
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 29 63 5 5 5
TUBB4B-201 TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 intact, hippie 43 65 7 7 1
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 36 51 4 4 1
TUT1-205 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 Not Cancer Driver No 1 hippie, biogrid 78 411 44 44 0
TYW3-201 TYW3 Q6IPR3 tRNA wybutosine-synthesizing protein 3 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 27 57 8 8 0
USP34-201 USP34 Q70CQ2 Ubiquitin carboxyl-terminal hydrolase 34 chr2 Not Cancer Driver No 1 hippie, biogrid 313 726 64 64 0
UTP25-202 UTP25 Q68CQ4 U3 small nucleolar RNA-associated protein 25 homolog chr1 Not Cancer Driver No 1 hippie 76 281 14 14 0
WDR77-201 WDR77 Q9BQA1 Methylosome protein WDR77 chr1 Not Cancer Driver No 1 intact, hippie 25 42 2 2 0
WTIP-202 WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 Not Cancer Driver No 1 intact, hippie 24 219 0 0 0
YBX1-201 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 intact, hippie 31 312 31 31 0
ZBP1-201 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 Not Cancer Driver No 1 intact 70 388 60 60 0
ZFP42-201 ZFP42 Q96MM3 Zinc finger protein 42 homolog chr4 Not Cancer Driver No 1 hippie, biogrid 111 77 23 23 0
ZSWIM8-223 ZSWIM8 A7E2V4 Zinc finger SWIM domain-containing protein 8 chr10 Not Cancer Driver No 1 hippie, biogrid 157 879 81 81 0