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AKR7A2-201 ,AKR7A2 ,O43488
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 17
  • Number of Interaction partner in hippie: 59
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAT1-201 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 29 32 1 1 10
ACTR10-201 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 35 29 2 2 0
ACTR1A-201 ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 34 14 0 0 0
ACTR1B-201 ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 1 hippie, biogrid 38 17 4 4 0
AKR7A2-201 AKR7A2 O43488 Aflatoxin B1 aldehyde reductase member 2 chr1 Not Cancer Driver No 1 hippie 24 93 3 3 0
AKR7A3-201 AKR7A3 O95154 Aflatoxin B1 aldehyde reductase member 3 chr1 Not Cancer Driver No 4 hippie, biogrid 32 50 3 3 0
APBB2-201 APBB2 Q92870 Amyloid beta precursor protein binding family B member 2 chr4 Not Cancer Driver No 1 hippie 72 420 39 39 0
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 25 183 12 12 0
BIRC2-201 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 49 85 7 7 0
BOD1L1-201 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 Not Cancer Driver No 1 hippie 276 3030 276 276 0
CCNB1-201 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 Not Cancer Driver No 1 hippie 30 146 10 10 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CFAP298-201 CFAP298 P57076 Cilia- and flagella-associated protein 298 chr21 Not Cancer Driver No 1 hippie 18 111 5 5 0
CHCHD10-202 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 Not Cancer Driver No 1 hippie 7 97 3 3 4
CISD3-204 CISD3 P0C7P0 CDGSH iron-sulfur domain-containing protein 3, mitochondrial chr17 Not Cancer Driver No 1 hippie 5 31 0 0 0
CTR9-201 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 hippie 109 385 29 29 0
CYGB-201 CYGB Q8WWM9 Cytoglobin chr17 Not Cancer Driver No 1 hippie 21 48 4 4 0
DCTN2-209 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 hippie, biogrid 34 254 23 23 0
DCTN3-201 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 1 hippie, biogrid 14 3 0 0 0
DCTN4-203 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 Not Cancer Driver No 1 hippie, biogrid 37 138 14 14 0
DCTN6-201 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 1 hippie, biogrid 17 45 0 0 0
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 106 520 65 65 0
DUSP12-201 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 Not Cancer Driver No 1 hippie, biogrid 19 30 1 1 0
EYA2-202 EYA2 O00167 Eyes absent homolog 2 chr20 Not Cancer Driver No 1 hippie 89 204 44 44 0
F2-201 F2 P00734 Prothrombin chr11 Not Cancer Driver No 1 hippie 85 98 20 20 9
FADD-201 FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 24 45 9 9 1
FAN1-201 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 Not Cancer Driver No 1 hippie 86 212 22 22 4
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 289 1249 137 137 8
HLA-B-249 HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 49 169 18 18 0
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 23 25 3 3 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 5 301 4 4 21
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 biogrid 139 282 37 37 63
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
KATNA1-203 KATNA1 O75449 Katanin p60 ATPase-containing subunit A1 chr6 Not Cancer Driver No 1 hippie 47 200 24 24 0
LEO1-201 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 hippie 57 611 53 53 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MCPH1-201 MCPH1 Q8NEM0 Microcephalin chr8 Not Cancer Driver No 1 hippie 84 454 46 46 1
MSH6-201 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 Census Yes 1 hippie 92 389 26 26 6
MTM1-203 MTM1 Q13496 Myotubularin chrX Not Cancer Driver No 1 hippie 84 79 8 8 49
MTMR12-203 MTMR12 Q9C0I1 Myotubularin-related protein 12 chr5 Not Cancer Driver No 1 hippie 71 131 8 8 0
MTMR14-201 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 45 150 6 6 2
MVB12A-201 MVB12A Q96EY5 Multivesicular body subunit 12A chr19 Not Cancer Driver No 1 hippie, biogrid 27 67 4 4 0
NDUFA4-201 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie 8 4 0 0 0
NDUFS3-201 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie 22 26 2 2 2
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
PCNA-201 PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 19 22 2 2 1
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PSMC1-201 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 hippie, biogrid 29 165 8 8 0
PTPN21-208 PTPN21 Q16825 Tyrosine-protein phosphatase non-receptor type 21 chr14 Not Cancer Driver No 1 hippie 120 599 78 78 0
PTPN22-201 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 Not Cancer Driver No 1 hippie 107 344 44 44 4
RALA-201 RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 29 34 3 3 4
SMC1A-201 SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX Census, Compendium Yes 1 hippie 142 717 83 83 17
TFCP2-201 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie, biogrid 40 169 12 12 0
TOLLIP-202 TOLLIP Q9H0E2 Toll-interacting protein chr11 Not Cancer Driver No 1 hippie 25 82 9 9 0
TRADD-201 TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 hippie 18 74 4 4 0
TRIM63-201 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie 26 71 6 6 0
TXN-202 TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 5 0 0 0 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 hippie 152 110 21 21 0
VPS37B-201 VPS37B Q9H9H4 Vacuolar protein sorting-associated protein 37B chr12 Not Cancer Driver No 1 hippie, biogrid 35 165 22 22 0
ZBTB1-207 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 50 273 17 17 0