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ALDH4A1-202 ,ALDH4A1 ,P30038
  • Number of Interaction partner in intact: 8
  • Number of Interaction partner in biogrid: 72
  • Number of Interaction partner in hippie: 86
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACO2-201 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 77 172 16 16 5
ACSM5-201 ACSM5 Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 133 87 24 24 0
ADH5-201 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 1 1 1
AHCY-201 AHCY P23526 Adenosylhomocysteinase chr20 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 6
AK4-201 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 24 2 2 0
ALDH4A1-202 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 48 47 8 8 1
ALDH6A1-202 ALDH6A1 Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 36 83 8 8 1
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARG1-203 ARG1 P05089 Arginase-1 chr6 Not Cancer Driver No 1 intact, hippie 27 83 8 8 9
ARRB1-202 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 37 154 11 11 0
AUH-202 AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 29 0 0 1
C1QBP-201 C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 5 5 2
CCR1-201 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
CFL1-201 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 17 4 0 0 0
CFL2-201 CFL2 Q9Y281 Cofilin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 1
CLIC1-208 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 28 27 4 4 0
CLIC4-201 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 23 49 4 4 0
CLPP-201 CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 15 83 7 7 3
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 13 5 1 1 1
CRYZ-201 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
CS-201 CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 38 13 2 2 0
DSTN-201 DSTN P60981 Destrin chr20 Not Cancer Driver No 2 hippie, biogrid 9 0 0 0 0
ENO1-201 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie, biogrid 37 21 2 2 0
ENO3-207 ENO3 P13929 Beta-enolase chr17 Not Cancer Driver No 1 hippie, biogrid 29 26 1 1 2
ENST00000647960 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 26 15 1 1 8
ESD-202 ESD P10768 S-formylglutathione hydrolase chr13 Not Cancer Driver No 1 hippie, biogrid 24 4 0 0 0
FABP3-201 FABP3 P05413 Fatty acid-binding protein, heart chr1 Not Cancer Driver No 1 hippie, biogrid 13 3 0 0 0
FAHD1-203 FAHD1 Q6P587 Acylpyruvase FAHD1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 7 12 0 0 0
FFAR1-201 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
FXN-203 FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 17 75 1 1 8
GLRX5-201 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 5 23 0 0 2
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 36 35 5 5 0
GPI-201 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 hippie, biogrid 56 73 10 10 23
GPR45-201 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 75 0 0 0 0
GSTP1-202 GSTP1 P09211 Glutathione S-transferase P chr11 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
HINT2-201 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 6 29 1 1 0
HMGCL-203 HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 8 2 2 17
IDH2-201 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 51 61 0 0 4
INHBA-201 INHBA P08476 Inhibin beta A chain chr7 Not Cancer Driver No 1 hippie, biogrid 121 154 54 54 0
LAP3-201 LAP3 P28838 Cytosol aminopeptidase chr4 Not Cancer Driver No 1 hippie, biogrid 39 100 8 8 0
LDHA-205 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 25 9 0 0 0
LDHAL6A-201 LDHAL6A Q6ZMR3 L-lactate dehydrogenase A-like 6A chr11 Not Cancer Driver No 1 hippie, biogrid 32 16 3 3 0
LDHAL6B-201 LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie, biogrid 37 17 1 1 0
LDHB-201 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 32 15 1 1 10
LRRC46-201 LRRC46 Q96FV0 Leucine-rich repeat-containing protein 46 chr17 Not Cancer Driver No 1 hippie, biogrid 25 159 13 13 0
LYPLAL1-202 LYPLAL1 Q5VWZ2 Lysophospholipase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 19 2 0 0 0
MALSU1-202 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 17 34 1 1 0
MDH2-201 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 26 8 1 1 3
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
METTL17-201 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 48 95 10 10 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MPST-201 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 18 72 9 9 0
MRM1-204 MRM1 Q6IN84 rRNA methyltransferase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 27 106 8 8 0
MRM2-201 MRM2 Q9UI43 rRNA methyltransferase 2, mitochondrial chr7 Not Cancer Driver No 1 hippie 33 15 1 1 1
MSRB2-201 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 11 66 6 6 0
MTPN-201 MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 7 11 3 3 0
MTRF1L-203 MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 17 185 5 5 0
NR2C2-206 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 41 187 13 13 0
OGT-202 OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 111 90 9 9 2
OIT3-201 OIT3 Q8WWZ8 Oncoprotein-induced transcript 3 protein chr10 Not Cancer Driver No 1 hippie, biogrid 64 31 4 4 0
OR2A4-201 OR2A4 O95047 Olfactory receptor 2A4 chr6 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
PDK1-201 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 32 49 7 7 0
PGM2-201 PGM2 Q96G03 Phosphopentomutase chr4 Not Cancer Driver No 1 hippie, biogrid 51 110 9 9 0
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 2 hippie, biogrid 48 23 3 3 4
PMPCB-201 PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 36 22 2 2 4
PTRHD1-201 PTRHD1 Q6GMV3 Putative peptidyl-tRNA hydrolase PTRHD1 chr2 Not Cancer Driver No 1 hippie, biogrid 10 22 2 2 0
PYCR1-201 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 18 66 6 6 7
QRSL1-202 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 44 63 2 2 2
RAB33A-201 RAB33A Q14088 Ras-related protein Rab-33A chrX Not Cancer Driver No 1 hippie, biogrid 27 12 2 2 0
RBBP4-202 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie 40 169 19 19 0
SOD2-210 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 21 25 3 3 0
SSBP1-201 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 6
STK16-201 STK16 O75716 Serine/threonine-protein kinase 16 chr2 Not Cancer Driver No 1 hippie, biogrid 25 48 2 2 0
TACO1-201 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 20 111 2 2 0
TBCA-202 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 7 30 2 2 0
TBRG4-201 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 56 61 1 1 0
TKT-207 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 hippie, biogrid 44 86 5 5 1
TMEM184A-201 TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 2 intact, hippie, biogrid 45 76 12 12 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRMT61B-201 TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 40 124 11 11 0
TRUB2-201 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 28 73 6 6 0
TSFM-212 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 21 74 4 4 2
TST-201 TST Q16762 Thiosulfate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 22 56 5 5 0
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 36 51 4 4 1
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
YARS2-201 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 47 63 8 8 2