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ARF1-201 ,ARF1 ,P84077
  • Number of Interaction partner in intact: 43
  • Number of Interaction partner in biogrid: 134
  • Number of Interaction partner in hippie: 205
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ACADM-202 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 39 42 2 2 19
ADCK1-201 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 Not Cancer Driver No 1 intact, hippie 49 7 2 2 0
ADCK2-201 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 hippie 46 9 1 1 0
ADCK5-201 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 intact, hippie 39 5 2 2 0
AGAP1-201 AGAP1 Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 121 407 59 59 0
AGAP2-203 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 97 755 61 61 0
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
AHSA1-201 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 33 147 14 14 0
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
AP1B1-202 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 1 hippie 84 119 7 7 1
AP1G1-201 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 Not Cancer Driver No 1 hippie 77 144 20 20 5
AP3B1-201 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 1 hippie 91 317 22 22 1
AP3D1-201 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 1 hippie 109 407 52 52 0
AP3S2-201 AP3S2 P59780 AP-3 complex subunit sigma-2 chr15 Not Cancer Driver No 1 hippie 19 0 0 0 0
AP4E1-201 AP4E1 Q9UPM8 AP-4 complex subunit epsilon-1 chr15 Not Cancer Driver No 1 hippie 97 148 23 23 2
AP4M1-201 AP4M1 O00189 AP-4 complex subunit mu-1 chr7 Not Cancer Driver No 1 hippie 47 64 7 7 0
ARF1-201 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 6 intact, hippie 22 4 2 2 2
ARF3-201 ARF3 P61204 ADP-ribosylation factor 3 chr12 Not Cancer Driver No 1 hippie, biogrid 8 4 0 0 0
ARF4-201 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 7 0 0 0 0
ARF5-201 ARF5 P84085 ADP-ribosylation factor 5 chr7 Not Cancer Driver No 2 hippie, biogrid 15 11 1 1 0
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 16 5 0 0 0
ARFGAP1-203 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 Not Cancer Driver No 2 hippie, biogrid 46 265 31 31 0
ARFGAP2-205 ARFGAP2 Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 45 346 27 27 0
ARFGAP3-201 ARFGAP3 Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 chr22 Not Cancer Driver No 1 hippie, biogrid 35 326 27 27 0
ARFIP1-201 ARFIP1 P53367 Arfaptin-1 chr4 Not Cancer Driver No 2 intact, hippie 26 147 14 14 0
ARFIP2-202 ARFIP2 P53365 Arfaptin-2 chr11 Not Cancer Driver No 1 hippie 29 144 12 12 0
ARHGAP21-202 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie 168 1613 140 140 0
ARHGAP31-201 ARHGAP31 Q2M1Z3 Rho GTPase-activating protein 31 chr3 Not Cancer Driver No 1 hippie, biogrid 206 1174 176 176 0
ARHGAP36-201 ARHGAP36 Q6ZRI8 Rho GTPase-activating protein 36 chrX Not Cancer Driver No 1 hippie, biogrid 163 132 54 54 0
ARIH2-201 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 Not Cancer Driver No 1 biogrid 45 85 9 9 0
ASAP1-202 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 132 587 79 79 0
ASAP2-201 ASAP2 O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie 101 454 49 49 0
ATF2-201 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 42 451 36 36 0
B3GAT1-201 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 59 93 24 24 0
B3GNT2-201 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 Not Cancer Driver No 1 biogrid 37 22 6 6 0
B4GALT1-201 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 Not Cancer Driver No 1 biogrid 28 129 9 9 0
B4GALT3-201 B4GALT3 O60512 Beta-1,4-galactosyltransferase 3 chr1 Not Cancer Driver No 1 biogrid 37 171 18 18 0
BAG1-210 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 19 197 5 5 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 34 150 23 23 0
C11orf52-201 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 14 109 11 11 0
CACNA1C-220 CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 Not Cancer Driver No 1 intact 350 708 123 123 25
CADPS-203 CADPS Q9ULU8 Calcium-dependent secretion activator 1 chr3 Not Cancer Driver No 1 hippie 201 336 41 41 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 31 213 13 13 0
CAND1-208 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 biogrid 118 88 6 6 0
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 biogrid 84 513 44 44 4
CCT3-201 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 53 95 11 11 0
CCT6A-201 CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie, biogrid 54 5 1 1 0
CDC7-201 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 1 intact 49 187 17 17 0
CDC73-201 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 78 210 32 32 2
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHCHD10-202 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 Not Cancer Driver No 1 hippie 7 97 3 3 4
CHCHD2-201 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 10 114 7 7 1
CHMP4B-201 CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 21 201 20 20 2
CHMP4C-201 CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 226 31 31 0
CHRM3-211 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 Not Cancer Driver No 1 hippie 155 137 35 35 0
CKAP4-201 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 44 412 36 36 0
COPB1-202 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 74 95 6 6 1
COPE-201 COPE O14579 Coatomer subunit epsilon chr19 Not Cancer Driver No 1 hippie 20 45 2 2 0
COPG1-201 COPG1 Q9Y678 Coatomer subunit gamma-1 chr3 Not Cancer Driver No 1 hippie 84 107 11 11 0
COQ2-206 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie, biogrid 16 25 0 0 17
COQ7-201 COQ7 Q99807 5-demethoxyubiquinone hydroxylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 16 5 0 0 1
COQ9-201 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 hippie 25 111 5 5 0
COX15-201 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 33 0 0 0 2
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
CUL3-201 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact 98 168 18 18 3
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
CYTH1-201 CYTH1 Q15438 Cytohesin-1 chr17 Not Cancer Driver No 1 hippie 41 93 7 7 0
CYTH2-213 CYTH2 Q99418 Cytohesin-2 chr19 Not Cancer Driver No 1 hippie 44 94 10 10 0
DENND1A-203 DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 Not Cancer Driver No 1 hippie 98 591 63 63 0
DENND1B-211 DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 Not Cancer Driver No 1 hippie 29 301 0 0 0
DEPDC5-264 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 Not Cancer Driver No 1 biogrid 162 580 66 66 7
DIRAS3-202 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 27 21 2 2 0
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 55 17 0 0 10
DNM1L-219 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 44 211 15 15 7
DPF2-205 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 49 179 21 21 5
DUSP22-201 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 1 hippie 76 0 0 0 0
DUX4-203 DUX4 Q9UBX2 Double homeobox protein 4 chr4 Not Cancer Driver No 1 hippie 0 407 0 0 0
EEF1G-201 EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie, biogrid 36 67 6 6 0
EIF2B1-201 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 2
ELOVL5-201 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 33 25 2 2 2
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 29 160 18 18 3
ENO1-201 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 intact 37 21 2 2 0
ENST00000455843 SEPTIN5 Q99719 Septin-5 chr22 Not Cancer Driver No 1 intact 34 77 4 4 0
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
ENST00000647960 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 26 15 1 1 8
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 249 315 32 32 1
ERGIC1-202 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 27 26 0 0 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
ETF1-201 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 intact 36 28 5 5 0
ETFA-203 ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 18 34 0 0 3
EZH2-203 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 biogrid 74 284 32 32 11
FAM136A-201 FAM136A Q96C01 Protein FAM136A chr2 Not Cancer Driver No 1 intact, hippie 11 13 1 1 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FBXW8-204 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 intact, hippie 48 121 4 4 0
FGD5-201 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 intact, hippie, biogrid 197 917 134 134 0
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GALE-216 GALE Q14376 UDP-glucose 4-epimerase chr1 Not Cancer Driver No 1 hippie, biogrid 25 24 2 2 16
GCNT2-216 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 Not Cancer Driver No 1 biogrid 27 3 0 0 0
GGA1-203 GGA1 Q9UJY5 ADP-ribosylation factor-binding protein GGA1 chr22 Not Cancer Driver No 1 hippie 57 385 23 23 0
GGA2-201 GGA2 Q9UJY4 ADP-ribosylation factor-binding protein GGA2 chr16 Not Cancer Driver No 1 hippie 62 241 26 26 0
GGA3-201 GGA3 Q9NZ52 ADP-ribosylation factor-binding protein GGA3 chr17 Not Cancer Driver No 1 hippie 51 421 29 29 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GLRX5-201 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 5 23 0 0 2
GORAB-202 GORAB Q5T7V8 RAB6-interacting golgin chr1 Not Cancer Driver No 1 hippie 45 285 35 35 0
GOSR2-232 GOSR2 O14653 Golgi SNAP receptor complex member 2 chr17 Not Cancer Driver No 1 hippie 16 106 10 10 2
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 intact 36 35 5 5 0
GPAM-201 GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 Not Cancer Driver No 1 hippie 70 83 4 4 0
GRK5-202 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 Not Cancer Driver No 1 hippie 58 105 12 12 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 intact 378 366 163 163 15
HDAC8-207 HDAC8 Q9BY41 Histone deacetylase 8 chrX Not Cancer Driver No 1 biogrid 47 33 3 3 4
HERC1-201 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie 350 1353 102 102 1
HOOK1-201 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 hippie 73 427 45 45 0
HOOK2-202 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact 70 489 49 49 0
HSD17B11-201 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
HSD3B7-202 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 37 27 4 4 2
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 biogrid 70 255 29 29 0
HTR2A-201 HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 Not Cancer Driver No 1 hippie 75 45 6 6 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
IMPDH2-201 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 52 6 1 1 0
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 139 282 37 37 63
IQGAP1-201 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact 137 351 25 25 0
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KDELR1-201 KDELR1 P24390 ER lumen protein-retaining receptor 1 chr19 Not Cancer Driver No 1 intact, hippie 21 0 0 0 0
KHSRP-201 KHSRP Q92945 Far upstream element-binding protein 2 chr19 Not Cancer Driver No 1 biogrid 68 684 65 65 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 3 intact, hippie, biogrid 771 7 2 2 22
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 29 55 4 4 1
LAMP3-201 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 57 223 34 34 0
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LDHA-205 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 25 9 0 0 0
LDHAL6A-201 LDHAL6A Q6ZMR3 L-lactate dehydrogenase A-like 6A chr11 Not Cancer Driver No 1 hippie, biogrid 32 16 3 3 0
LDHAL6B-201 LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie, biogrid 37 17 1 1 0
LDHB-201 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 32 15 1 1 10
LDHC-207 LDHC P07864 L-lactate dehydrogenase C chain chr11 Not Cancer Driver No 1 hippie, biogrid 48 0 0 0 0
LNPK-201 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 48 256 34 34 0
LRIF1-201 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie 76 520 45 45 0
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 78 85 10 10 0
LYRM2-208 LYRM2 Q9NU23 LYR motif-containing protein 2 chr6 Not Cancer Driver No 1 intact, hippie 4 31 3 3 0
LYRM7-201 LYRM7 Q5U5X0 Complex III assembly factor LYRM7 chr5 Not Cancer Driver No 1 intact, hippie 2 29 0 0 1
MAIP1-202 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 23 12 0 0 0
MAN1A1-201 MAN1A1 P33908 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA chr6 Not Cancer Driver No 1 biogrid 81 134 20 20 0
MAN1B1-202 MAN1B1 Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase chr9 Not Cancer Driver No 1 biogrid 54 173 10 10 2
MAN2A1-201 MAN2A1 Q16706 Alpha-mannosidase 2 chr5 Not Cancer Driver No 1 biogrid 121 83 6 6 0
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 5 328 5 5 0
MDM4-203 MDM4 O15151 Protein Mdm4 chr1 Census, Compendium Yes 1 hippie 33 203 15 15 1
MKRN2-201 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 30 145 7 7 0
MMS19-209 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 54 11 0 0 0
MTF2-201 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 Not Cancer Driver No 1 biogrid 43 225 18 18 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NCOR1-201 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 biogrid 265 2348 258 258 0
NOA1-201 NOA1 Q8NC60 Nitric oxide-associated protein 1 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 55 228 20 20 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 25 249 19 19 0
NPRL2-201 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 biogrid 24 10 2 2 1
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
OPRM1-202 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 1 hippie 71 59 17 17 0
PAICS-207 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie, biogrid 16 35 1 1 0
PANX1-201 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 45 5 5 2
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 8 30 0 0 6
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
PEX3-201 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 18 24 0 0 2
PICK1-201 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie 36 49 1 1 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 46 99 8 8 24
PIP5K1A-202 PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 Not Cancer Driver No 1 hippie 53 217 22 22 0
PLD1-201 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 2 hippie, biogrid 126 133 21 21 1
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie 71 98 5 5 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHA8-205 PLEKHA8 Q96JA3 Pleckstrin homology domain-containing family A member 8 chr7 Not Cancer Driver No 1 hippie 47 128 15 15 0
PLEKHG4-202 PLEKHG4 Q58EX7 Puratrophin-1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 104 296 26 26 0
PLEKHG6-210 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 Not Cancer Driver No 1 hippie, biogrid 83 471 53 53 0
PLIN2-201 PLIN2 Q99541 Perilipin-2 chr9 Not Cancer Driver No 1 hippie 30 126 8 8 0
POLE3-202 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 Not Cancer Driver No 1 biogrid 5 117 5 5 0
PRKACB-205 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 hippie, biogrid 35 26 2 2 3
PRNP-201 PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 28 117 8 8 19
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie 36 141 17 17 0
PTPN18-201 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 42 138 8 8 0
PXN-201 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 41 342 14 14 0
RAB11A-201 RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 2 hippie, biogrid 12 43 2 2 0
RAB11B-201 RAB11B Q15907 Ras-related protein Rab-11B chr19 Not Cancer Driver No 1 hippie, biogrid 22 39 2 2 2
RAB1A-203 RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 2 hippie, biogrid 9 38 2 2 0
RAB1B-201 RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 Not Cancer Driver No 2 hippie, biogrid 18 40 3 3 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 3 hippie, biogrid 15 58 3 3 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RAB3B-201 RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 26 26 6 6 0
RAB4A-201 RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 15 32 8 8 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 20 67 9 9 0
RAB5B-201 RAB5B P61020 Ras-related protein Rab-5B chr12 Not Cancer Driver No 1 hippie, biogrid 15 43 3 3 0
RAB5C-201 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 3 hippie, biogrid 17 51 2 2 0
RAB6A-202 RAB6A P20340 Ras-related protein Rab-6A chr11 Not Cancer Driver No 1 hippie, biogrid 17 45 5 5 0
RAB6B-201 RAB6B Q9NRW1 Ras-related protein Rab-6B chr3 Not Cancer Driver No 1 hippie, biogrid 28 42 4 4 0
RAB8A-201 RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 hippie 30 26 3 3 0
RAB9A-202 RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 7 21 0 0 0
RABGEF1-201 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 Not Cancer Driver No 1 biogrid 59 175 27 27 0
RAD52-202 RAD52 P43351 DNA repair protein RAD52 homolog chr12 Not Cancer Driver No 1 intact, hippie 30 252 24 24 0
RALA-201 RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 29 34 3 3 4
RBM39-201 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 53 228 16 16 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 50 20 1 1 0
RICTOR-202 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 biogrid 144 365 34 34 0
RNF130-205 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 Not Cancer Driver No 1 biogrid 32 43 2 2 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
SAR1A-204 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 Not Cancer Driver No 2 hippie, biogrid 14 4 0 0 0
SCYL1-201 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 Not Cancer Driver No 1 hippie 58 312 23 23 0
SEC23B-211 SEC23B Q15437 Protein transport protein Sec23B chr20 Not Cancer Driver No 1 biogrid 72 82 4 4 7
SEC23IP-201 SEC23IP Q9Y6Y8 SEC23-interacting protein chr10 Not Cancer Driver No 1 biogrid 90 374 33 33 0
SEC24A-202 SEC24A O95486 Protein transport protein Sec24A chr5 Not Cancer Driver No 1 biogrid 71 409 38 38 0
SEC24C-202 SEC24C P53992 Protein transport protein Sec24C chr10 Not Cancer Driver No 1 biogrid 100 403 31 31 0
SEC31A-205 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 biogrid 103 520 44 44 0
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 6 60 5 5 0
SEC62-201 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 12 211 9 9 0
SEPTIN5-209 SEPTIN5 Q99719 Septin-5 chr22 Not Cancer Driver No 1 intact 34 76 4 4 0
SLC30A5-202 SLC30A5 Q8TAD4 Proton-coupled zinc antiporter SLC30A5 chr5 Not Cancer Driver No 1 biogrid 37 33 0 0 0
SLC33A1-207 SLC33A1 O00400 Acetyl-coenzyme A transporter 1 chr3 Not Cancer Driver No 1 biogrid 43 54 5 5 2
SLC39A3-201 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 biogrid 35 0 0 0 0
SLC39A7-202 SLC39A7 Q92504 Zinc transporter SLC39A7 chr6 Not Cancer Driver No 1 biogrid 31 192 7 7 3
SNAP25-201 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 Not Cancer Driver No 1 hippie 46 178 38 38 1
SOAT1-201 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 55 51 1 1 0
SPAG9-201 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 Not Cancer Driver No 1 hippie 95 844 62 62 0
SPATA20-202 SPATA20 Q8TB22 Spermatogenesis-associated protein 20 chr17 Not Cancer Driver No 1 hippie 70 164 16 16 0
SPRYD4-201 SPRYD4 Q8WW59 SPRY domain-containing protein 4 chr12 Not Cancer Driver No 1 hippie 13 1 0 0 0
SSR1-201 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 17 115 5 5 0
STIM1-201 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 55 386 35 35 12
STK4-202 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie 49 233 20 20 0
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 39 153 16 16 0
STX7-202 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 21 165 9 9 0
TBL1XR1-214 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 Census, Compendium Yes 1 biogrid 68 136 14 14 4
TET2-203 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 150 1671 139 139 1
TMED10-201 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie 19 15 2 2 0
TMED2-201 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 intact, hippie 16 25 2 2 0
TMEM106A-208 TMEM106A Q96A25 Transmembrane protein 106A chr17 Not Cancer Driver No 1 intact, hippie 21 9 0 0 0
TMPO-202 TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie, biogrid 50 414 32 32 0
TRAPPC12-201 TRAPPC12 Q8WVT3 Trafficking protein particle complex subunit 12 chr2 Not Cancer Driver No 1 biogrid 68 320 25 25 0
TRAPPC13-202 TRAPPC13 A5PLN9 Trafficking protein particle complex subunit 13 chr5 Not Cancer Driver No 1 biogrid 25 19 0 0 0
TRAPPC2L-201 TRAPPC2L Q9UL33 Trafficking protein particle complex subunit 2-like protein chr16 Not Cancer Driver No 1 biogrid 13 0 0 0 1
TRPV2-201 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 Not Cancer Driver No 1 intact, hippie 82 179 20 20 0
TSC1-201 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 biogrid 94 735 53 53 11
TSC2-201 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 biogrid 156 568 40 40 49
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 36 51 4 4 1
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBE2J1-201 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 Not Cancer Driver No 1 biogrid 23 160 15 15 0
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 biogrid 25 32 4 4 0
UNK-205 UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 60 513 33 33 0
USP39-201 USP39 Q53GS9 U4/U6.U5 tri-snRNP-associated protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 34 128 6 6 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 152 110 21 21 0
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 25 36 4 4 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VPS51-201 VPS51 Q9UID3 Vacuolar protein sorting-associated protein 51 homolog chr11 Not Cancer Driver No 1 biogrid 58 150 8 8 1
WBP11-201 WBP11 Q9Y2W2 WW domain-binding protein 11 chr12 Not Cancer Driver No 1 hippie, biogrid 39 608 33 33 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
ZC3H7A-201 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 63 225 17 17 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 127 16 16 0