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ARHGEF16-203 ,ARHGEF16 ,Q5VV41
  • Number of Interaction partner in intact: 5
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 78
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCD3-202 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 hippie, biogrid 52 21 1 1 0
ACAT1-201 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 29 32 1 1 10
ADAM10-201 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 Not Cancer Driver No 1 hippie 73 156 18 18 4
ANKFY1-201 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 70 186 20 20 0
ATP1A2-201 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 162 162 21 21 14
ATP5PO-201 ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 hippie 17 9 2 2 0
BOLL-203 BOLL Q8N9W6 Protein boule-like chr2 Not Cancer Driver No 1 hippie 48 80 16 16 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CEP55-201 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 1 intact, hippie 34 264 15 15 0
CHCHD2-201 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie, biogrid 10 114 7 7 1
CKAP5-210 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 hippie 149 634 48 48 0
COQ8A-201 COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 hippie 69 169 21 21 10
DLAT-201 DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 50 297 35 35 0
DLG1-269 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 2 hippie, biogrid 89 460 48 48 0
DPP8-203 DPP8 Q6V1X1 Dipeptidyl peptidase 8 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 73 71 5 5 0
ELMO1-201 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 Not Cancer Driver No 1 hippie 158 98 21 21 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EPB41L3-201 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1 hippie, biogrid 240 697 165 165 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 147 188 33 33 3
FGD6-201 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 Not Cancer Driver No 1 hippie, biogrid 141 809 79 79 0
GAPDHS-201 GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 Not Cancer Driver No 1 hippie, biogrid 52 111 12 12 0
GAR1-201 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 Not Cancer Driver No 1 hippie, biogrid 5 141 0 0 0
GBF1-223 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 161 670 62 62 0
HACD3-201 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 Not Cancer Driver No 1 hippie 15 10 0 0 0
HDAC2-205 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 34 145 11 11 0
HMGN1-204 HMGN1 P05114 Non-histone chromosomal protein HMG-14 chr21 Not Cancer Driver No 1 hippie, biogrid 11 101 11 11 0
HMGN3-202 HMGN3 Q15651 High mobility group nucleosome-binding domain-containing protein 3 chr6 Not Cancer Driver No 1 hippie, biogrid 11 99 11 11 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 129 16 2 2 10
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie, biogrid 82 252 28 28 0
IFT122-203 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 2 hippie, biogrid 108 54 5 5 5
KPNA2-201 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 hippie, biogrid 54 130 14 14 0
LASP1-201 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 26 200 22 22 0
LBR-201 LBR Q14739 Delta(14)-sterol reductase LBR chr1 Not Cancer Driver No 1 hippie, biogrid 70 130 11 11 5
LIN7C-201 LIN7C Q9NUP9 Protein lin-7 homolog C chr11 Not Cancer Driver No 1 hippie, biogrid 17 102 8 8 0
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 50 547 34 34 117
LNX1-201 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 90 261 33 33 0
LRIF1-201 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie 76 520 45 45 0
LYPLA1-201 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 14 12 0 0 0
MAGED1-201 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX Not Cancer Driver No 1 hippie 42 457 37 37 0
MAPK1IP1L-201 MAPK1IP1L Q8NDC0 MAPK-interacting and spindle-stabilizing protein-like chr14 Not Cancer Driver No 1 hippie 16 246 16 16 0
MAPRE1-201 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie, biogrid 17 109 5 5 0
MECP2-201 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 44 482 43 43 32
MGA-201 MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 hippie, biogrid 273 2321 212 212 0
MRPL53-201 MRPL53 Q96EL3 Large ribosomal subunit protein mL53 chr2 Not Cancer Driver No 1 hippie, biogrid 19 22 1 1 0
NUDT21-201 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 15 37 2 2 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PML-201 PML P29590 Protein PML chr15 Census, Compendium Yes 2 intact, hippie, biogrid 87 312 28 28 0
PPIB-201 PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 hippie, biogrid 16 16 0 0 1
PPIL4-201 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 Not Cancer Driver No 1 hippie, biogrid 40 237 23 23 0
PRKCI-201 PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie, biogrid 79 120 12 12 0
QPCTL-201 QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 32 22 0 0 0
RABL3-201 RABL3 Q5HYI8 Rab-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 31 1 0 0 1
RBFOX2-210 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 1 hippie, biogrid 31 163 18 18 0
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 50 20 1 1 0
RIF1-205 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 Not Cancer Driver No 1 hippie, biogrid 194 1364 112 112 0
RPL22L1-201 RPL22L1 Q6P5R6 Ribosomal protein eL22-like chr3 Not Cancer Driver No 1 hippie, biogrid 6 22 2 2 0
RPS27A-201 RPS27A P62979 Ubiquitin-ribosomal protein eS31 fusion protein chr2 Not Cancer Driver No 1 hippie, biogrid 13 47 2 2 0
SCRIB-201 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 2 hippie, biogrid 169 1071 117 117 2
SF3A1-201 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie, biogrid 65 632 53 53 0
SFN-201 SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 16 75 3 3 0
SHMT2-201 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 45 58 4 4 1
SNRNP70-206 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie, biogrid 28 417 27 27 0
SNTB2-201 SNTB2 Q13425 Beta-2-syntrophin chr16 Not Cancer Driver No 1 hippie, biogrid 17 163 1 1 0
STIP1-201 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 54 270 28 28 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 62 233 23 23 0
TFG-201 TFG Q92734 Protein TFG chr3 Census, Compendium Yes 1 hippie 25 292 19 19 2
TMEM160-201 TMEM160 Q9NX00 Transmembrane protein 160 chr19 Not Cancer Driver No 1 hippie, biogrid 3 46 0 0 0
UBAC1-201 UBAC1 Q9BSL1 Ubiquitin-associated domain-containing protein 1 chr9 Not Cancer Driver No 2 hippie, biogrid 31 245 21 21 0
UTRN-204 UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 hippie, biogrid 352 1287 137 137 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie, biogrid 84 33 5 5 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 19 110 3 3 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 hippie, biogrid 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 19 81 7 7 0