Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADH5-201 | ADH5 | P11766 | Alcohol dehydrogenase class-3 | chr4 | Not Cancer Driver | No | 1 | hippie | 23 | 2 | 1 | 1 | 1 |
| ADSL-208 | ADSL | P30566 | Adenylosuccinate lyase | chr22 | Not Cancer Driver | No | 1 | hippie | 48 | 36 | 8 | 8 | 26 |
| AHR-201 | AHR | P35869 | Aryl hydrocarbon receptor | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 95 | 353 | 55 | 55 | 0 |
| AHRR-211 | AHRR | A9YTQ3 | Aryl hydrocarbon receptor repressor | chr5 | Not Cancer Driver | No | 1 | hippie | 90 | 458 | 53 | 53 | 0 |
| AIP-201 | AIP | O00170 | AH receptor-interacting protein | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 64 | 7 | 7 | 1 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 99 | 158 | 19 | 19 | 4 |
| ARL14-201 | ARL14 | Q8N4G2 | ADP-ribosylation factor-like protein 14 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 16 | 15 | 2 | 2 | 0 |
| ARNT-202 | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | Census | Yes | 2 | intact, hippie | 61 | 511 | 47 | 47 | 0 |
| ARNT2-201 | ARNT2 | Q9HBZ2 | Aryl hydrocarbon receptor nuclear translocator 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 83 | 450 | 55 | 55 | 0 |
| ARPC2-202 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 49 | 7 | 7 | 0 |
| ASF1A-201 | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 69 | 2 | 2 | 0 |
| BAG2-201 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 112 | 7 | 7 | 0 |
| BCAT1-201 | BCAT1 | P54687 | Branched-chain-amino-acid aminotransferase, cytosolic | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 53 | 8 | 2 | 2 | 0 |
| BECN1-213 | BECN1 | Q14457 | Beclin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 36 | 190 | 15 | 15 | 0 |
| BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 167 | 1466 | 127 | 127 | 34 |
| C1QTNF2-202 | C1QTNF2 | Q9BXJ5 | Complement C1q tumor necrosis factor-related protein 2 | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 16 | 148 | 3 | 3 | 0 |
| CAD-201 | CAD | P27708 | CAD protein | chr2 | Not Cancer Driver | No | 1 | hippie | 211 | 368 | 27 | 27 | 1 |
| CALCOCO1-218 | CALCOCO1 | Q9P1Z2 | Calcium-binding and coiled-coil domain-containing protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 74 | 489 | 48 | 48 | 0 |
| CALM1-201 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 12 | 115 | 10 | 10 | 6 |
| CALM2-201 | CALM1 | P0DP23 | Calmodulin-1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 13 | 115 | 8 | 8 | 6 |
| CALM3-201 | CALM1 | P0DP23 | Calmodulin-1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 13 | 115 | 8 | 8 | 6 |
| CALML3-201 | CALML3 | P27482 | Calmodulin-like protein 3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 106 | 26 | 26 | 0 |
| CAND1-208 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 118 | 88 | 6 | 6 | 0 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | Census | Yes | 1 | hippie | 19 | 64 | 1 | 1 | 0 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | Census | Yes | 1 | hippie | 26 | 71 | 7 | 7 | 0 |
| CCND2-201 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | Census, Compendium | Yes | 1 | hippie | 29 | 30 | 5 | 5 | 3 |
| CCNE1-201 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | Census | Yes | 1 | hippie | 44 | 142 | 15 | 15 | 0 |
| CD44-208 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 547 | 50 | 50 | 0 |
| CDK4-201 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 38 | 52 | 3 | 3 | 2 |
| CDK6-202 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | Census | Yes | 1 | hippie | 25 | 24 | 3 | 3 | 1 |
| CDK9-201 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 40 | 34 | 2 | 2 | 0 |
| CDKN2A-201 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | hippie | 151 | 83 | 81 | 81 | 30 |
| CDKN2B-201 | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | Not Cancer Driver | No | 1 | hippie | 14 | 67 | 2 | 2 | 0 |
| CDKN2C-202 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | Census, Compendium | Yes | 1 | hippie | 17 | 49 | 5 | 5 | 0 |
| CHD4-206 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 312 | 978 | 118 | 118 | 6 |
| CIAO3-201 | CIAO3 | Q9H6Q4 | Cytosolic iron-sulfur assembly component 3 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 68 | 1 | 1 | 0 |
| CIC-206 | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 216 | 1552 | 207 | 207 | 0 |
| CNBP-201 | CNBP | P62633 | CCHC-type zinc finger nucleic acid binding protein | chr3 | Census | Yes | 1 | hippie | 8 | 19 | 0 | 0 | 0 |
| CREB1-201 | CREB1 | P16220 | Cyclic AMP-responsive element-binding protein 1 | chr2 | Census | Yes | 1 | intact, hippie | 14 | 278 | 13 | 13 | 0 |
| CSNK2A1-201 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 47 | 75 | 6 | 6 | 4 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 363 | 288 | 291 | 291 | 11 |
| CTTN-201 | CTTN | Q14247 | Src substrate cortactin | chr11 | Not Cancer Driver | No | 1 | hippie | 55 | 466 | 37 | 37 | 0 |
| CUL2-203 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 64 | 66 | 2 | 2 | 0 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 54 | 102 | 2 | 2 | 0 |
| CYP1B1-205 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | Not Cancer Driver | No | 1 | hippie | 41 | 33 | 3 | 3 | 39 |
| DCAF15-201 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 35 | 173 | 14 | 14 | 0 |
| DIABLO-207 | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | Not Cancer Driver | No | 1 | hippie | 20 | 54 | 2 | 2 | 1 |
| DNAJA2-201 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 34 | 174 | 18 | 18 | 0 |
| DNM2-201 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | hippie | 95 | 271 | 32 | 32 | 16 |
| DPM1-203 | DPM1 | O60762 | Dolichol-phosphate mannosyltransferase subunit 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 24 | 29 | 1 | 1 | 3 |
| EGLN1-201 | EGLN1 | Q9GZT9 | Egl nine homolog 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 206 | 4 | 4 | 2 |
| EGLN3-201 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 0 | 0 | 0 |
| ELAVL1-201 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 54 | 43 | 5 | 5 | 0 |
| ELOB-203 | ELOB | Q15370 | Elongin-B | chr16 | Not Cancer Driver | No | 1 | hippie | 5 | 69 | 3 | 3 | 0 |
| ELOC-206 | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 1 | hippie | 13 | 25 | 3 | 3 | 0 |
| ENST00000637807 | AHR | P35869 | Aryl hydrocarbon receptor | chr7 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 90 | 304 | 51 | 51 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 203 | 1792 | 84 | 84 | 1 |
| EPAS1-201 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | Census, Compendium | Yes | 5 | intact, hippie, biogrid | 109 | 451 | 54 | 54 | 4 |
| EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | Compendium | Yes | 1 | hippie | 147 | 188 | 33 | 33 | 3 |
| ERBB2-201 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | Census, Compendium | Yes | 1 | hippie | 249 | 315 | 32 | 32 | 1 |
| ESR1-201 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 92 | 198 | 19 | 19 | 2 |
| ESR2-202 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 69 | 92 | 10 | 10 | 1 |
| FEM1A-201 | FEM1A | Q9BSK4 | Protein fem-1 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 162 | 13 | 13 | 0 |
| FEV-201 | FEV | Q99581 | Protein FEV | chr2 | Census | Yes | 1 | hippie | 8 | 55 | 0 | 0 | 0 |
| FGFR4-201 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | hippie | 101 | 163 | 27 | 27 | 0 |
| FLOT2-202 | FLOT2 | Q14254 | Flotillin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 52 | 20 | 2 | 2 | 0 |
| FOXN1-203 | FOXN1 | O15353 | Forkhead box protein N1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 83 | 485 | 62 | 62 | 2 |
| FOXR2-201 | FOXR2 | Q6PJQ5 | Forkhead box protein R2 | chrX | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 58 | 129 | 33 | 33 | 0 |
| FYN-202 | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 64 | 71 | 11 | 11 | 0 |
| FZR1-202 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 64 | 184 | 24 | 24 | 2 |
| GIP-201 | GIP | P09681 | Gastric inhibitory polypeptide | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 68 | 14 | 14 | 0 |
| GLIS1-201 | GLIS1 | Q8NBF1 | Zinc finger protein GLIS1 | chr1 | Not Cancer Driver | No | 1 | hippie | 83 | 409 | 51 | 51 | 0 |
| GLIS2-202 | GLIS2 | Q9BZE0 | Zinc finger protein GLIS2 | chr16 | Not Cancer Driver | No | 1 | hippie | 27 | 300 | 15 | 15 | 0 |
| GMNN-201 | GMNN | O75496 | Geminin | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 211 | 19 | 19 | 1 |
| GNAI1-228 | GNAI1 | P63096 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 39 | 11 | 2 | 2 | 9 |
| GNAI2-202 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | Compendium | Yes | 1 | hippie | 37 | 24 | 0 | 0 | 0 |
| GNAS-214 | GNAS | Q5JWF2 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas | chr20 | Census, Compendium | Yes | 1 | hippie | 112 | 718 | 33 | 33 | 2 |
| GTF2F1-201 | GTF2F1 | P35269 | General transcription factor IIF subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 47 | 427 | 35 | 35 | 0 |
| GTF2F2-201 | GTF2F2 | P13984 | General transcription factor IIF subunit 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 12 | 112 | 6 | 6 | 0 |
| HDAC1-201 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 135 | 5 | 5 | 0 |
| HERC2-201 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | Compendium | Yes | 1 | hippie | 517 | 971 | 113 | 113 | 1 |
| HEY1-202 | HEY1 | Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | chr8 | Census | Yes | 1 | hippie | 26 | 172 | 12 | 12 | 0 |
| HEY2-201 | HEY2 | Q9UBP5 | Hairy/enhancer-of-split related with YRPW motif protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 50 | 181 | 21 | 21 | 0 |
| HGF-201 | HGF | P14210 | Hepatocyte growth factor | chr7 | Compendium | Yes | 1 | hippie | 196 | 43 | 16 | 16 | 0 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | Census | Yes | 3 | hippie, biogrid | 54 | 436 | 28 | 28 | 0 |
| HIF1AN-201 | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 24 | 78 | 5 | 5 | 0 |
| HIF3A-205 | HIF3A | Q9Y2N7 | Hypoxia-inducible factor 3-alpha | chr19 | Not Cancer Driver | No | 1 | hippie | 113 | 364 | 74 | 74 | 0 |
| HK1-202 | HK1 | P19367 | Hexokinase-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 90 | 76 | 13 | 13 | 6 |
| HMGB1-203 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | Not Cancer Driver | No | 1 | hippie | 10 | 202 | 7 | 7 | 0 |
| HNF4A-201 | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 113 | 127 | 44 | 44 | 5 |
| HSP90AA1-201 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 44 | 258 | 15 | 15 | 0 |
| HSPA1A-201 | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 20 | 200 | 10 | 10 | 0 |
| HSPA1B-201 | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 200 | 7 | 7 | 0 |
| HSPA2-201 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 286 | 30 | 30 | 0 |
| HSPA8-224 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 82 | 252 | 28 | 28 | 0 |
| HSPA9-201 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 47 | 284 | 19 | 19 | 2 |
| HSPB1-201 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 19 |
| HSPD1-202 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 45 | 83 | 1 | 1 | 2 |
| ICAM1-201 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 52 | 253 | 25 | 25 | 0 |
| IKBKG-206 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | Not Cancer Driver | No | 1 | hippie | 5 | 301 | 4 | 4 | 21 |
| IRAK4-212 | IRAK4 | Q9NWZ3 | Interleukin-1 receptor-associated kinase 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 50 | 116 | 17 | 17 | 2 |
| JUN-201 | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 26 | 283 | 17 | 17 | 0 |
| JUP-203 | JUP | P14923 | Junction plakoglobin | chr17 | Not Cancer Driver | No | 1 | hippie | 81 | 242 | 24 | 24 | 0 |
| KLC1-204 | KLC1 | Q07866 | Kinesin light chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 50 | 293 | 27 | 27 | 0 |
| KPNA1-201 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 1 | hippie | 48 | 122 | 16 | 16 | 0 |
| KPNA3-201 | KPNA3 | O00505 | Importin subunit alpha-4 | chr13 | Not Cancer Driver | No | 1 | hippie | 47 | 108 | 7 | 7 | 5 |
| KPNA5-202 | KPNA5 | O15131 | Importin subunit alpha-6 | chr6 | Not Cancer Driver | No | 1 | hippie | 48 | 133 | 8 | 8 | 0 |
| KPNA6-201 | KPNA6 | O60684 | Importin subunit alpha-7 | chr1 | Not Cancer Driver | No | 1 | hippie | 50 | 97 | 13 | 13 | 0 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 771 | 7 | 2 | 2 | 22 |
| LATS2-201 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | hippie | 101 | 690 | 57 | 57 | 0 |
| LDHA-205 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie | 25 | 9 | 0 | 0 | 0 |
| LOX-201 | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | Compendium | Yes | 1 | hippie, biogrid | 31 | 172 | 8 | 8 | 4 |
| LRRC59-201 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie | 26 | 123 | 13 | 13 | 0 |
| LSM8-201 | LSM8 | O95777 | U6 snRNA-associated Sm-like protein LSm8 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 9 | 3 | 0 | 0 | 0 |
| LYN-202 | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie | 78 | 85 | 10 | 10 | 0 |
| MAD2L1-201 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 12 | 1 | 1 | 0 |
| MAP2K3-202 | MAP2K3 | P46734 | Dual specificity mitogen-activated protein kinase kinase 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 74 | 76 | 19 | 19 | 0 |
| MAP2K5-201 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | Not Cancer Driver | No | 1 | hippie | 26 | 85 | 6 | 6 | 0 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 22 | 25 | 0 | 0 | 0 |
| MATR3-201 | MATR3 | P43243 | Matrin-3 | chr5 | Not Cancer Driver | No | 1 | hippie | 81 | 613 | 61 | 61 | 3 |
| MPRIP-202 | MPRIP | Q6WCQ1 | Myosin phosphatase Rho-interacting protein | chr17 | Not Cancer Driver | No | 1 | hippie | 87 | 736 | 72 | 72 | 0 |
| MTA3-201 | MTA3 | Q9BTC8 | Metastasis-associated protein MTA3 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 169 | 12 | 12 | 0 |
| MYC-206 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 72 | 325 | 41 | 41 | 0 |
| MYH10-201 | MYH10 | P35580 | Myosin-10 | chr17 | Not Cancer Driver | No | 1 | hippie | 197 | 1135 | 103 | 103 | 1 |
| MYH9-201 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | hippie | 247 | 1124 | 126 | 126 | 13 |
| MYL6-218 | MYL6 | P60660 | Myosin light polypeptide 6 | chr12 | Not Cancer Driver | No | 1 | hippie | 10 | 17 | 1 | 1 | 0 |
| MYO1B-204 | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | Not Cancer Driver | No | 1 | hippie | 103 | 35 | 3 | 3 | 0 |
| MYO1C-220 | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 1 | hippie | 86 | 66 | 9 | 9 | 0 |
| NANOG-201 | NANOG | Q9H9S0 | Homeobox protein NANOG | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 171 | 28 | 28 | 0 |
| NCOA1-202 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 135 | 1217 | 107 | 107 | 0 |
| NCOA2-201 | NCOA2 | Q15596 | Nuclear receptor coactivator 2 | chr8 | Census, Compendium | Yes | 1 | hippie | 152 | 1283 | 134 | 134 | 0 |
| NCOA7-203 | NCOA7 | Q8NI08 | Nuclear receptor coactivator 7 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 82 | 538 | 42 | 42 | 0 |
| NCOR2-202 | NCOR2 | Q9Y618 | Nuclear receptor corepressor 2 | chr12 | Census, Compendium | Yes | 1 | intact, hippie | 167 | 2369 | 167 | 167 | 0 |
| NDOR1-206 | NDOR1 | Q9UHB4 | NADPH-dependent diflavin oxidoreductase 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 68 | 5 | 5 | 0 |
| NF2-202 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 49 | 252 | 18 | 18 | 16 |
| NONO-201 | NONO | Q15233 | Non-POU domain-containing octamer-binding protein | chrX | Census, Compendium | Yes | 1 | hippie | 70 | 349 | 46 | 46 | 0 |
| NPAS1-208 | NPAS1 | Q99742 | Neuronal PAS domain-containing protein 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 311 | 21 | 21 | 0 |
| NPAS3-202 | NPAS3 | Q8IXF0 | Neuronal PAS domain-containing protein 3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 135 | 507 | 76 | 76 | 0 |
| NPAS4-201 | NPAS4 | Q8IUM7 | Neuronal PAS domain-containing protein 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 175 | 429 | 91 | 91 | 0 |
| OR6K3-202 | OR6K3 | Q8NGY3 | Olfactory receptor 6K3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 6 | 0 | 0 | 0 |
| PAX7-203 | PAX7 | P23759 | Paired box protein Pax-7 | chr1 | Census | Yes | 1 | intact, hippie | 78 | 396 | 61 | 61 | 1 |
| PCCB-201 | PCCB | P05166 | Propionyl-CoA carboxylase beta chain, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 64 | 8 | 8 | 24 |
| PDGFRA-201 | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | Census, Compendium | Yes | 1 | hippie | 213 | 173 | 36 | 36 | 2 |
| PDK1-201 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 32 | 49 | 7 | 7 | 0 |
| PFKFB3-203 | PFKFB3 | Q16875 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 51 | 97 | 12 | 12 | 0 |
| PFKFB4-201 | PFKFB4 | Q16877 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 53 | 44 | 3 | 3 | 0 |
| PFKM-203 | PFKM | P08237 | ATP-dependent 6-phosphofructokinase, muscle type | chr12 | Not Cancer Driver | No | 1 | hippie | 56 | 70 | 5 | 5 | 8 |
| PIAS2-204 | PIAS2 | O75928 | E3 SUMO-protein ligase PIAS2 | chr18 | Not Cancer Driver | No | 1 | hippie | 57 | 209 | 19 | 19 | 0 |
| PML-201 | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 87 | 312 | 28 | 28 | 0 |
| PPA1-202 | PPA1 | Q15181 | Inorganic pyrophosphatase | chr10 | Not Cancer Driver | No | 1 | hippie | 22 | 24 | 0 | 0 | 0 |
| PPP1CA-203 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 6 | 6 | 0 |
| PPP2R1A-201 | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | Census, Compendium | Yes | 1 | hippie | 169 | 0 | 0 | 0 | 4 |
| PSMD2-201 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 71 | 136 | 11 | 11 | 0 |
| PTGES3-201 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 8 | 52 | 2 | 2 | 0 |
| PXN-201 | PXN | P49023 | Paxillin | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 342 | 14 | 14 | 0 |
| RAC1-201 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 61 | 2 | 0 | 0 | 6 |
| RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | Census, Compendium | Yes | 1 | hippie | 64 | 169 | 30 | 30 | 18 |
| RANBP1-201 | RANBP1 | P43487 | Ran-specific GTPase-activating protein | chr22 | Not Cancer Driver | No | 1 | hippie | 13 | 137 | 11 | 11 | 0 |
| RB1-201 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | Census, Compendium | Yes | 1 | hippie | 89 | 282 | 26 | 26 | 21 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 53 | 401 | 32 | 32 | 0 |
| RPL18-208 | RPL18 | Q07020 | Large ribosomal subunit protein eL18 | chr19 | Not Cancer Driver | No | 1 | hippie | 14 | 98 | 6 | 6 | 0 |
| RPL19-201 | RPL19 | P84098 | Large ribosomal subunit protein eL19 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 121 | 14 | 14 | 0 |
| RPL27-201 | RPL27 | P61353 | Large ribosomal subunit protein eL27 | chr17 | Not Cancer Driver | No | 1 | hippie | 18 | 13 | 3 | 3 | 0 |
| RPL35A-211 | RPL35A | P18077 | Large ribosomal subunit protein eL33 | chr3 | Not Cancer Driver | No | 1 | hippie | 5 | 25 | 0 | 0 | 1 |
| RPL4-201 | RPL4 | P36578 | Large ribosomal subunit protein uL4 | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 222 | 15 | 15 | 0 |
| RPL7-201 | RPL7 | P18124 | Large ribosomal subunit protein uL30 | chr8 | Not Cancer Driver | No | 1 | hippie | 11 | 40 | 0 | 0 | 0 |
| RPS5-201 | RPS5 | P46782 | Small ribosomal subunit protein uS7 | chr19 | Not Cancer Driver | No | 1 | hippie | 31 | 41 | 5 | 5 | 0 |
| RTL10-201 | RTL10 | Q7L3V2 | Protein Bop | chr22 | Not Cancer Driver | No | 1 | hippie | 35 | 200 | 17 | 17 | 0 |
| RTN4-202 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 81 | 868 | 50 | 50 | 0 |
| RUVBL1-201 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 41 | 67 | 5 | 5 | 0 |
| RUVBL2-206 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 52 | 100 | 11 | 11 | 0 |
| S100A8-202 | S100A8 | P05109 | Protein S100-A8 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 8 | 4 | 4 | 0 |
| S100A9-201 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 76 | 8 | 8 | 0 |
| SELENBP1-201 | SELENBP1 | Q13228 | Methanethiol oxidase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 31 | 3 | 3 | 2 |
| SENP6-205 | SENP6 | Q9GZR1 | Sentrin-specific protease 6 | chr6 | Not Cancer Driver | No | 1 | hippie | 78 | 616 | 31 | 31 | 0 |
| SFN-201 | SFN | P31947 | 14-3-3 protein sigma | chr1 | Not Cancer Driver | No | 1 | hippie | 16 | 75 | 3 | 3 | 0 |
| SHARPIN-202 | SHARPIN | Q9H0F6 | Sharpin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 237 | 13 | 13 | 0 |
| SHMT1-201 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 38 | 32 | 6 | 6 | 0 |
| SIM1-202 | SIM1 | P81133 | Single-minded homolog 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 171 | 377 | 99 | 99 | 0 |
| SIM2-201 | SIM2 | Q14190 | Single-minded homolog 2 | chr21 | Not Cancer Driver | No | 2 | hippie, biogrid | 48 | 262 | 9 | 9 | 0 |
| SIPA1L3-201 | SIPA1L3 | O60292 | Signal-induced proliferation-associated 1-like protein 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 228 | 1266 | 160 | 160 | 0 |
| SLC25A11-201 | SLC25A11 | Q02978 | Mitochondrial 2-oxoglutarate/malate carrier protein | chr17 | Not Cancer Driver | No | 1 | hippie | 31 | 16 | 1 | 1 | 3 |
| SLC7A5-201 | SLC7A5 | Q01650 | Large neutral amino acids transporter small subunit 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 35 | 0 | 0 | 0 |
| SMAD9-202 | SMAD9 | O15198 | Mothers against decapentaplegic homolog 9 | chr13 | Not Cancer Driver | No | 1 | hippie | 64 | 132 | 14 | 14 | 1 |
| SMARCA5-201 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | Not Cancer Driver | No | 1 | hippie | 73 | 364 | 26 | 26 | 0 |
| SMG7-201 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 95 | 664 | 67 | 67 | 0 |
| SOX2-201 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | intact, hippie | 32 | 312 | 32 | 32 | 0 |
| SOX6-219 | SOX6 | P35712 | Transcription factor SOX-6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 745 | 93 | 93 | 0 |
| SP1-201 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 67 | 601 | 53 | 53 | 0 |
| SP7-202 | SP7 | Q8TDD2 | Transcription factor Sp7 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 46 | 332 | 32 | 32 | 0 |
| SPTBN1-202 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 218 | 877 | 86 | 86 | 16 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie | 40 | 130 | 10 | 10 | 1 |
| STK11-201 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | Census, Compendium | Yes | 1 | hippie | 63 | 135 | 12 | 12 | 9 |
| STRBP-201 | STRBP | Q96SI9 | Spermatid perinuclear RNA-binding protein | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 46 | 307 | 21 | 21 | 0 |
| SUDS3-204 | SUDS3 | Q9H7L9 | Sin3 histone deacetylase corepressor complex component SDS3 | chr12 | Not Cancer Driver | No | 1 | hippie | 16 | 249 | 11 | 11 | 0 |
| SUGT1-202 | SUGT1 | Q9Y2Z0 | Protein SGT1 homolog | chr13 | Not Cancer Driver | No | 1 | hippie | 21 | 119 | 0 | 0 | 0 |
| SYT7-201 | SYT7 | O43581 | Synaptotagmin-7 | chr11 | Not Cancer Driver | No | 1 | hippie | 50 | 132 | 19 | 19 | 0 |
| TACC3-201 | TACC3 | Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 76 | 719 | 67 | 67 | 0 |
| TEAD2-201 | TEAD2 | Q15562 | Transcriptional enhancer factor TEF-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 54 | 220 | 25 | 25 | 0 |
| TERF2IP-201 | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 312 | 12 | 12 | 0 |
| TGM2-201 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 82 | 108 | 19 | 19 | 0 |
| TIMM8A-201 | TIMM8A | O60220 | Mitochondrial import inner membrane translocase subunit Tim8 A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 22 | 1 | 1 | 1 |
| TMPO-202 | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie | 50 | 414 | 32 | 32 | 0 |
| TNFAIP1-201 | TNFAIP1 | Q13829 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 39 | 2 | 2 | 0 |
| TNNC2-201 | TNNC2 | P02585 | Troponin C, skeletal muscle | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 88 | 10 | 10 | 2 |
| TNS3-201 | TNS3 | Q68CZ2 | Tensin-3 | chr7 | Not Cancer Driver | No | 1 | hippie | 175 | 873 | 113 | 113 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2742 | 282 | 1364 | 1364 | 60 |
| TRIM28-201 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 67 | 431 | 32 | 32 | 0 |
| TRIP11-201 | TRIP11 | Q15643 | Thyroid receptor-interacting protein 11 | chr14 | Census, Compendium | Yes | 1 | hippie | 147 | 1374 | 113 | 113 | 2 |
| TUBB2A-201 | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | Not Cancer Driver | No | 1 | hippie | 32 | 70 | 5 | 5 | 2 |
| UBE2I-203 | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
| VEGFA-226 | VEGFA | P15692 | Vascular endothelial growth factor A, long form | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 215 | 9 | 9 | 0 |
| VHL-201 | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 85 | 117 | 15 | 15 | 84 |
| XPO1-201 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 84 | 33 | 5 | 5 | 0 |
| XRCC6-202 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 49 | 140 | 8 | 8 | 0 |
| ZSCAN18-217 | ZSCAN18 | Q8TBC5 | Zinc finger and SCAN domain-containing protein 18 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 402 | 64 | 64 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|