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ARPC5-202 ,ARPC5 ,O15511
  • Number of Interaction partner in intact: 36
  • Number of Interaction partner in biogrid: 29
  • Number of Interaction partner in hippie: 83
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARSD1-202 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 Not Cancer Driver No 1 hippie 41 158 20 20 0
ABCE1-201 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 50 36 4 4 0
ACTA1-202 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 intact 63 48 13 13 67
ACTR2-201 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 5 intact, hippie, biogrid 28 6 1 1 0
ACTR3-201 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 8 intact, hippie, biogrid 24 16 2 2 0
ACTR3B-201 ACTR3B Q9P1U1 Actin-related protein 3B chr7 Not Cancer Driver No 4 intact, hippie, biogrid 41 5 0 0 0
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 101 771 75 75 2
ANP32B-201 ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie 8 117 1 1 0
ARPC1A-201 ARPC1A Q92747 Actin-related protein 2/3 complex subunit 1A chr7 Not Cancer Driver No 8 intact, hippie, biogrid 39 27 7 7 0
ARPC1B-222 ARPC1B O15143 Actin-related protein 2/3 complex subunit 1B chr7 Not Cancer Driver No 10 intact, hippie, biogrid 28 34 1 1 0
ARPC2-202 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 5 intact, hippie, biogrid 29 49 7 7 0
ARPC3-201 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 8 intact, hippie, biogrid 10 26 5 5 0
ARPC4-201 ARPC4 P59998 Actin-related protein 2/3 complex subunit 4 chr3 Not Cancer Driver No 6 intact, hippie, biogrid 11 3 0 0 1
ARPC5L-202 ARPC5L Q9BPX5 Actin-related protein 2/3 complex subunit 5-like protein chr9 Not Cancer Driver No 2 hippie, biogrid 3 48 0 0 0
ARRB1-202 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 37 154 11 11 0
ASCC3-204 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 202 87 7 7 0
ATG16L1-203 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 54 240 19 19 1
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BICD2-202 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 83 546 51 51 10
BRD3-201 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 64 567 53 53 0
BTF3L4-201 BTF3L4 Q96K17 Transcription factor BTF3 homolog 4 chr1 Not Cancer Driver No 1 hippie 12 131 8 8 0
CACNA1C-220 CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 Not Cancer Driver No 1 intact 350 708 123 123 25
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie 28 245 16 16 0
CAPZA2-201 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 21 19 0 0 0
CAPZB-201 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 hippie, biogrid 17 66 1 1 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 21 23 1 1 1
CHURC1-203 CHURC1 Q8WUH1 Protein Churchill chr14 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CTBP1-201 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 30 123 8 8 1
DAPK1-202 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 149 116 12 12 0
DBN1-202 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 63 512 56 56 0
DCPS-201 DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 32 55 5 5 1
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EIF3H-209 EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 hippie, biogrid 24 109 7 7 0
EIF4B-201 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie 80 588 76 76 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ENST00000649896 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 2 hippie, biogrid 45 121 15 15 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 21 23 1 1 1
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
GGACT-207 GGACT Q9BVM4 Gamma-glutamylaminecyclotransferase chr13 Not Cancer Driver No 1 hippie, biogrid 1 51 0 0 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie 62 111 20 20 43
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 21 10 0 0 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 intact 378 366 163 163 15
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HTRA4-201 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 42 15 0 0 0
HUS1-201 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 19 17 1 1 0
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MAPKAPK2-202 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 Not Cancer Driver No 1 hippie 27 92 4 4 0
METTL1-202 METTL1 Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase chr12 Not Cancer Driver No 1 hippie 28 89 9 9 0
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 59 153 18 18 2
MTPAP-201 MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 50 138 14 14 1
MYH11-201 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 244 1186 144 144 2
MYO5C-201 MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 138 395 31 31 0
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
NUPR1-201 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
PDPK1-202 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 intact, hippie 23 121 9 9 0
PKD2-201 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 1 intact 88 376 30 30 9
POLA2-201 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 2 hippie, biogrid 49 102 15 15 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 60 44 3 3 3
PPP2R1B-206 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 hippie 45 17 1 1 0
PRKACA-201 PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 49 24 0 0 2
PRKD2-201 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 2 hippie, biogrid 89 247 26 26 0
RAD21-201 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 2 intact, hippie, biogrid 84 421 56 56 3
RASA1-201 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 118 181 19 19 3
RBCK1-202 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 42 141 14 14 2
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 intact 20 22 3 3 0
RNASEH2B-201 RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 Not Cancer Driver No 1 intact, hippie 24 84 8 8 15
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 10 4 1 1 0
SH3BGRL-201 SH3BGRL O75368 Adapter SH3BGRL chrX Not Cancer Driver No 1 intact, hippie 17 51 7 7 0
SH3GL1-201 SH3GL1 Q99961 Endophilin-A2 chr19 Census Yes 1 hippie 37 247 27 27 0
SIK2-201 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 Not Cancer Driver No 1 hippie 71 525 44 44 0
SOX2-201 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 32 312 32 32 0
SYNPO-202 SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 70 923 69 69 0
TAX1BP1-202 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 43 429 29 29 0
TCP11L1-201 TCP11L1 Q9NUJ3 T-complex protein 11-like protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 41 74 4 4 0
TMIGD1-201 TMIGD1 Q6UXZ0 Transmembrane and immunoglobulin domain-containing protein 1 chr17 Not Cancer Driver No 1 intact 26 6 1 1 0
TOM1L1-221 TOM1L1 O75674 TOM1-like protein 1 chr17 Not Cancer Driver No 1 hippie 44 269 28 28 0
TPRKB-201 TPRKB Q9Y3C4 EKC/KEOPS complex subunit TPRKB chr2 Not Cancer Driver No 1 hippie 12 0 0 0 2
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRO-201 TRO Q12816 Trophinin chrX Not Cancer Driver No 2 hippie, biogrid 152 593 43 43 0
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 intact, hippie, biogrid 50 39 2 2 4
UBB-201 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 2 intact, hippie, biogrid 15 103 6 6 0
VMP1-201 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 39 68 7 7 0
VPS13A-202 VPS13A Q96RL7 Intermembrane lipid transfer protein VPS13A chr9 Not Cancer Driver No 2 hippie, biogrid 258 208 16 16 6
VPS13C-209 VPS13C Q709C8 Intermembrane lipid transfer protein VPS13C chr15 Not Cancer Driver No 2 intact, hippie, biogrid 310 435 38 38 1
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZNG1C-201 ZNG1C Q5JTY5 Zinc-regulated GTPase metalloprotein activator 1C chr9 Not Cancer Driver No 1 intact 7 62 0 0 0
ZWINT-203 ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie 49 170 36 36 0