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CAPN2-201 ,CAPN2 ,P17655
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 47
  • Number of Interaction partner in hippie: 137
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALDH7A1-201 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 Not Cancer Driver No 1 hippie 41 26 0 0 8
ASNS-202 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 Not Cancer Driver No 1 hippie 58 11 0 0 3
ATG5-204 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 33 25 6 6 1
ATIC-201 ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 Census Yes 1 hippie 49 25 1 1 1
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 25 183 12 12 0
B3GNT2-201 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 37 22 6 6 0
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 1 hippie 21 73 5 5 0
BID-211 BID P55957 BH3-interacting domain death agonist chr22 Not Cancer Driver No 1 hippie 17 75 5 5 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
CAPN1-201 CAPN1 P07384 Calpain-1 catalytic subunit chr11 Not Cancer Driver No 3 intact, hippie, biogrid 51 32 0 0 1
CAPN11-201 CAPN11 Q9UMQ6 Calpain-11 chr6 Not Cancer Driver No 1 biogrid 70 103 10 10 0
CAPN12-201 CAPN12 Q6ZSI9 Calpain-12 chr19 Not Cancer Driver No 1 biogrid 69 62 7 7 0
CAPN3-205 CAPN3 P20807 Calpain-3 chr15 Not Cancer Driver No 1 biogrid 79 169 8 8 46
CAPN9-201 CAPN9 O14815 Calpain-9 chr1 Not Cancer Driver No 1 biogrid 80 82 13 13 0
CAPNS1-201 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 2 hippie, biogrid 21 59 5 5 0
CAPNS2-201 CAPNS2 Q96L46 Calpain small subunit 2 chr16 Not Cancer Driver No 1 hippie 13 56 1 1 0
CASP6-201 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 19 24 4 4 0
CASP9-201 CASP9 P55211 Caspase-9 chr1 Census Yes 1 hippie 26 71 7 7 0
CAST-207 CAST P20810 Calpastatin chr5 Not Cancer Driver No 3 intact, hippie, biogrid 52 712 52 52 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 intact, hippie 23 2 0 0 0
CCZ1-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 24 43 0 0 0
CCZ1B-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 18 43 2 2 0
CD109-201 CD109 Q6YHK3 CD109 antigen chr6 Not Cancer Driver No 1 hippie, biogrid 151 54 9 9 0
CDK5R1-201 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 Not Cancer Driver No 1 hippie 29 103 10 10 0
CEBPA-201 CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 hippie 10 343 10 10 1
CFAP410-202 CFAP410 O43822 Cilia- and flagella-associated protein 410 chr21 Not Cancer Driver No 1 hippie 15 135 7 7 7
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 4 intact, hippie 216 145 9 9 130
CHORDC1-201 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 37 119 12 12 0
CHP1-201 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 Not Cancer Driver No 1 intact 22 70 13 13 0
COPS5-201 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 27 32 4 4 0
CSTF2T-201 CSTF2T Q9H0L4 Cleavage stimulation factor subunit 2 tau variant chr10 Not Cancer Driver No 1 hippie, biogrid 64 509 56 56 0
CTH-202 CTH P32929 Cystathionine gamma-lyase chr1 Not Cancer Driver No 1 hippie 31 50 3 3 2
DCP2-201 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 hippie 40 167 21 21 0
DIAPH3-205 DIAPH3 Q9NSV4 Protein diaphanous homolog 3 chr13 Not Cancer Driver No 1 hippie, biogrid 138 493 62 62 0
DMWD-201 DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 61 378 23 23 0
DNASE2B-202 DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 Not Cancer Driver No 1 hippie, biogrid 38 14 2 2 0
DOCK7-219 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 Not Cancer Driver No 1 hippie, biogrid 183 455 33 33 0
DUSP19-202 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 Not Cancer Driver No 1 hippie 18 15 2 2 0
DUSP28-202 DUSP28 Q4G0W2 Dual specificity phosphatase 28 chr2 Not Cancer Driver No 1 hippie 9 55 4 4 0
DUX4-203 DUX4 Q9UBX2 Double homeobox protein 4 chr4 Not Cancer Driver No 1 hippie 0 407 0 0 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EIF2AK4-201 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 Not Cancer Driver No 1 hippie, biogrid 113 496 34 34 2
ENG-202 ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 47 114 11 11 29
ERCC6L-201 ERCC6L Q2NKX8 DNA excision repair protein ERCC-6-like chrX Not Cancer Driver No 1 hippie, biogrid 85 533 47 47 0
F2RL1-201 F2RL1 P55085 Proteinase-activated receptor 2 chr5 Not Cancer Driver No 1 hippie 33 7 0 0 0
FAM9C-202 FAM9C Q8IZT9 Protein FAM9C chrX Not Cancer Driver No 1 hippie, biogrid 19 158 17 17 0
FBXL12-201 FBXL12 Q9NXK8 F-box/LRR-repeat protein 12 chr19 Not Cancer Driver No 1 hippie 32 0 0 0 0
FMN2-201 FMN2 Q9NZ56 Formin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 222 1327 218 218 0
FNTA-201 FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 Not Cancer Driver No 1 hippie, biogrid 29 92 9 9 0
FNTB-201 FNTB P49356 Protein farnesyltransferase subunit beta chr14 Not Cancer Driver No 1 hippie, biogrid 25 31 1 1 0
GAS2-202 GAS2 O43903 Growth arrest-specific protein 2 chr11 Not Cancer Driver No 1 hippie 54 93 14 14 0
GMDS-202 GMDS O60547 GDP-mannose 4,6 dehydratase chr6 Not Cancer Driver No 1 hippie 42 53 6 6 0
GNS-201 GNS P15586 N-acetylglucosamine-6-sulfatase chr12 Not Cancer Driver No 1 intact, hippie, biogrid 36 22 0 0 3
GRK2-201 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 1 hippie 60 87 6 6 0
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 34 148 6 6 0
HK1-202 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie 90 76 13 13 6
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie, biogrid 33 290 22 22 4
HTRA4-201 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 42 15 0 0 0
IMMP2L-202 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 32 29 6 6 0
JAK3-201 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 131 63 4 4 7
KNG1-203 KNG1 P01042 Kininogen-1 chr3 Not Cancer Driver No 1 hippie 100 297 55 55 1
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 88 408 46 46 0
LACTB-201 LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 29 123 2 2 0
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 intact, hippie 29 55 4 4 1
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LOXL2-201 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 Not Cancer Driver No 1 intact 103 39 3 3 0
LSP1-201 LSP1 P33241 Lymphocyte-specific protein 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 42 334 40 40 0
LZTR1-221 LZTR1 Q8N653 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 1 hippie, biogrid 125 106 18 18 26
MAN2A2-216 MAN2A2 P49641 Alpha-mannosidase 2x chr15 Not Cancer Driver No 1 hippie, biogrid 80 53 3 3 0
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 52 2 0 0 6
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 100 750 99 99 17
MCM8-205 MCM8 Q9UJA3 DNA helicase MCM8 chr20 Not Cancer Driver No 1 hippie, biogrid 61 188 11 11 1
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 1 hippie, biogrid 59 153 18 18 2
MSN-201 MSN P26038 Moesin chrX Census, Compendium Yes 1 hippie 78 286 39 39 1
MTDH-201 MTDH Q86UE4 Protein LYRIC chr8 Not Cancer Driver No 1 hippie 45 518 44 44 0
MTO1-201 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 51 61 2 2 1
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYO9A-201 MYO9A B2RTY4 Unconventional myosin-IXa chr15 Not Cancer Driver No 1 hippie, biogrid 235 975 101 101 0
NAE1-201 NAE1 Q13564 NEDD8-activating enzyme E1 regulatory subunit chr16 Not Cancer Driver No 1 hippie 27 69 2 2 0
NFKBIA-201 NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 hippie 34 102 10 10 1
NMT1-201 NMT1 P30419 Glycylpeptide N-tetradecanoyltransferase 1 chr17 Not Cancer Driver No 1 intact, hippie 51 169 17 17 0
NPRL3-211 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 Not Cancer Driver No 1 hippie, biogrid 34 160 18 18 0
NSFL1C-201 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie 33 267 22 22 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUDCD1-201 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 49 38 2 2 0
NUPR1-201 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 intact, hippie 10 82 10 10 0
OFD1-201 OFD1 O75665 Centriole and centriolar satellite protein OFD1 chrX Not Cancer Driver No 1 hippie, biogrid 77 476 25 25 5
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 intact, hippie 41 80 13 13 1
PAFAH1B1-202 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 hippie 37 83 11 11 7
PAPSS1-201 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 Not Cancer Driver No 1 hippie 66 83 9 9 0
PBXIP1-202 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 69 606 60 60 0
PCYT2-203 PCYT2 Q99447 Ethanolamine-phosphate cytidylyltransferase chr17 Not Cancer Driver No 1 hippie 36 101 11 11 0
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie 61 147 18 18 0
PIK3C2A-206 PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 Not Cancer Driver No 1 hippie, biogrid 119 351 24 24 0
PIP5K1A-202 PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 Not Cancer Driver No 1 hippie, biogrid 53 217 22 22 0
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 68 120 14 14 0
PLP1-223 PLP1 P60201 Myelin proteolipid protein chrX Not Cancer Driver No 1 intact, hippie 36 5 0 0 64
PLPBP-201 PLPBP O94903 Pyridoxal phosphate homeostasis protein chr8 Not Cancer Driver No 1 hippie 25 96 10 10 3
PMS1-213 PMS1 P54277 PMS1 protein homolog 1 chr2 Census Yes 1 hippie, biogrid 86 284 31 31 0
POLR3A-201 POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 hippie, biogrid 115 113 12 12 16
PPIP5K2-202 PPIP5K2 O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 chr5 Not Cancer Driver No 1 hippie, biogrid 101 420 35 35 1
PRPF40A-213 PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 intact, hippie 39 695 29 29 0
PSG8-201 PSG8 Q9UQ74 Pregnancy-specific beta-1-glycoprotein 8 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 122 48 15 15 0
PTMA-201 PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 3 113 3 3 0
PTP4A2-219 PTP4A2 Q12974 Protein tyrosine phosphatase type IVA 2 chr1 Not Cancer Driver No 1 hippie 13 3 0 0 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 2 intact, hippie 36 141 17 17 0
PTPRN-201 PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 Not Cancer Driver No 1 hippie 116 500 63 63 0
RAN-212 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 18 14 0 0 0
RPL23-206 RPL23 P62829 Large ribosomal subunit protein uL14 chr17 Not Cancer Driver No 1 hippie, biogrid 11 29 2 2 0
SMG8-201 SMG8 Q8ND04 Nonsense-mediated mRNA decay factor SMG8 chr17 Not Cancer Driver No 1 hippie, biogrid 110 415 45 45 1
SNRPE-202 SNRPE P62304 Small nuclear ribonucleoprotein E chr1 Not Cancer Driver No 1 hippie 10 0 0 0 1
SOX2-201 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 32 312 32 32 0
SPANXN4-202 SPANXN4 Q5MJ08 Sperm protein associated with the nucleus on the X chromosome N4 chrX Not Cancer Driver No 1 hippie, biogrid 10 99 10 10 0
ST13-201 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 intact 27 298 21 21 0
STAT2-201 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 Not Cancer Driver No 1 hippie, biogrid 60 178 17 17 1
STK26-202 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 1 hippie 44 119 14 14 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 29 113 11 11 11
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie 10 76 7 7 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUMO3-201 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 6 86 4 4 0
TASOR-211 TASOR Q9UK61 Protein TASOR chr3 Not Cancer Driver No 1 hippie 87 779 36 36 0
TATDN1-201 TATDN1 Q6P1N9 Deoxyribonuclease TATDN1 chr8 Not Cancer Driver No 1 hippie 16 0 0 0 0
TEDC1-204 TEDC1 Q86SX3 Tubulin epsilon and delta complex protein 1 chr14 Not Cancer Driver No 1 hippie 16 162 4 4 0
TNS1-223 TNS1 Q9HBL0 Tensin-1 chr2 Not Cancer Driver No 1 intact, hippie 200 1299 145 145 0
TOP2A-201 TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie, biogrid 115 509 46 46 0
TUBB2A-201 TUBB2A Q13885 Tubulin beta-2A chain chr6 Not Cancer Driver No 1 hippie 32 70 5 5 2
TUFM-201 TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie 36 51 4 4 1
TUT4-204 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 Not Cancer Driver No 1 hippie 145 775 77 77 0
TWF2-201 TWF2 Q6IBS0 Twinfilin-2 chr3 Not Cancer Driver No 1 hippie 28 59 8 8 0
UBA3-202 UBA3 Q8TBC4 NEDD8-activating enzyme E1 catalytic subunit chr3 Not Cancer Driver No 1 hippie 32 44 4 4 0
UBE2I-203 UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBXN1-202 UBXN1 Q04323 UBX domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 30 271 29 29 0
USP54-222 USP54 Q70EL1 Inactive ubiquitin carboxyl-terminal hydrolase 54 chr10 Not Cancer Driver No 1 hippie, biogrid 131 1268 103 103 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WDR36-203 WDR36 Q8NI36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 1 hippie, biogrid 82 89 5 5 2
WDR37-201 WDR37 Q9Y2I8 WD repeat-containing protein 37 chr10 Not Cancer Driver No 1 hippie, biogrid 45 155 11 11 8
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 24 41 1 1 0
ZDHHC17-201 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 61 50 6 6 0
ZFYVE21-202 ZFYVE21 Q9BQ24 Zinc finger FYVE domain-containing protein 21 chr14 Not Cancer Driver No 1 hippie 22 19 0 0 0
ZRANB1-201 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 65 158 16 16 0