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CAPZB-201 ,CAPZB ,P47756
  • Number of Interaction partner in intact: 68
  • Number of Interaction partner in biogrid: 84
  • Number of Interaction partner in hippie: 257
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ABRA-201 ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 Not Cancer Driver No 1 hippie, biogrid 83 285 69 69 0
ACO2-201 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie 77 172 16 16 5
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 2 intact, hippie 96 43 5 5 4
ACTC1-201 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 90 48 14 14 11
ACTR10-201 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 35 29 2 2 0
ACTR1A-201 ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 34 14 0 0 0
ACTR1B-201 ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 38 17 4 4 0
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
AHCY-201 AHCY P23526 Adenosylhomocysteinase chr20 Not Cancer Driver No 1 hippie 47 0 0 0 6
AKT3-217 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 1 intact, hippie 71 131 19 19 3
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 101 771 75 75 2
ANO7-201 ANO7 Q6IWH7 Anoctamin-7 chr2 Not Cancer Driver No 1 hippie 111 150 23 23 0
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 116 443 38 38 144
ARAP1-204 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 115 401 26 26 0
ARHGAP17-201 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 Not Cancer Driver No 1 hippie 68 547 35 35 0
ARPC2-202 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 1 hippie, biogrid 29 49 7 7 0
ARPC3-201 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie, biogrid 10 26 5 5 0
ARPC5-202 ARPC5 O15511 Actin-related protein 2/3 complex subunit 5 chr1 Not Cancer Driver No 1 hippie, biogrid 11 67 5 5 0
ARPC5L-202 ARPC5L Q9BPX5 Actin-related protein 2/3 complex subunit 5-like protein chr9 Not Cancer Driver No 1 hippie, biogrid 3 48 0 0 0
BAG1-210 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 19 197 5 5 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 30 572 30 30 7
BAG5-201 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 27 63 5 5 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 88 681 64 64 0
BCCIP-201 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 Not Cancer Driver No 1 hippie, biogrid 23 99 13 13 0
BCL2L1-201 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 22 55 2 2 0
BICD1-210 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 105 661 70 70 0
BICD2-202 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 83 546 51 51 10
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BLNK-201 BLNK Q8WV28 B-cell linker protein chr10 Not Cancer Driver No 1 hippie 54 380 48 48 0
BMI1-201 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 2 intact, hippie 34 150 23 23 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BTF3-202 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 2 hippie, biogrid 20 192 18 18 0
CAPZA1-201 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 8 intact, hippie, biogrid 31 42 3 3 0
CAPZA2-201 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 5 hippie, biogrid 21 19 0 0 0
CARMIL1-201 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 Not Cancer Driver No 1 hippie 133 540 68 68 0
CARMIL2-201 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 Not Cancer Driver No 1 hippie 111 670 55 55 4
CCDC33-212 CCDC33 Q8N5R6 Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 1 intact, hippie 100 621 57 57 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CD2AP-201 CD2AP Q9Y5K6 CD2-associated protein chr6 Not Cancer Driver No 2 hippie, biogrid 51 458 38 38 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 21 23 1 1 1
CDC73-201 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 78 210 32 32 2
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 40 34 2 2 0
CEP152-202 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 biogrid 128 990 74 74 2
CEP295-201 CEP295 Q9C0D2 Centrosomal protein of 295 kDa chr11 Not Cancer Driver No 1 biogrid 65 2045 53 53 0
CEP63-216 CEP63 Q96MT8 Centrosomal protein of 63 kDa chr3 Not Cancer Driver No 1 intact 77 508 50 50 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 4 intact, hippie 216 145 9 9 130
CIC-206 CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 216 1552 207 207 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
CNOT1-201 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 236 465 45 45 12
CNOT10-201 CNOT10 Q9H9A5 CCR4-NOT transcription complex subunit 10 chr3 Not Cancer Driver No 1 hippie, biogrid 41 218 11 11 0
CNOT11-201 CNOT11 Q9UKZ1 CCR4-NOT transcription complex subunit 11 chr2 Not Cancer Driver No 1 hippie, biogrid 38 217 10 10 0
CNOT2-201 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 2 hippie, biogrid 56 354 46 46 0
CNOT3-201 CNOT3 O75175 CCR4-NOT transcription complex subunit 3 chr19 Census, Compendium Yes 1 hippie, biogrid 91 538 57 57 3
CNOT6-201 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 Not Cancer Driver No 1 hippie, biogrid 42 66 4 4 0
CNOT6L-201 CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie, biogrid 43 37 2 2 0
CNOT7-201 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 hippie, biogrid 20 21 0 0 0
CNOT8-201 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 22 6 0 0 0
CNOT9-201 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 32 30 0 0 0
COX15-201 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 33 0 0 0 2
CPVL-201 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 1 hippie, biogrid 53 0 0 0 0
CRK-201 CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 24 197 19 19 0
CTBP1-201 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 30 123 8 8 1
CTNNBL1-201 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 biogrid 53 158 18 18 1
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
CYLD-203 CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 76 213 21 21 3
DAPK1-202 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 149 116 12 12 0
DBN1-202 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 63 512 56 56 0
DCAF15-201 DCAF15 Q66K64 DDB1- and CUL4-associated factor 15 chr19 Not Cancer Driver No 1 hippie 35 173 14 14 0
DCAF4-202 DCAF4 Q8WV16 DDB1- and CUL4-associated factor 4 chr14 Not Cancer Driver No 1 intact, hippie 42 118 6 6 0
DCTN1-226 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 5 intact, hippie, biogrid 129 818 84 84 9
DCTN2-209 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 2 hippie, biogrid 34 254 23 23 0
DCTN3-201 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 1 hippie, biogrid 14 3 0 0 0
DCTN4-203 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 Not Cancer Driver No 2 hippie, biogrid 37 138 14 14 0
DCTN5-201 DCTN5 Q9BTE1 Dynactin subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
DCTN6-201 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 2 hippie, biogrid 17 45 0 0 0
DCTPP1-201 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 Not Cancer Driver No 1 hippie 12 88 7 7 0
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DDX39B-202 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 36 34 6 6 0
DDX53-201 DDX53 Q86TM3 Probable ATP-dependent RNA helicase DDX53 chrX Not Cancer Driver No 1 hippie, biogrid 76 200 28 28 0
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 106 520 65 65 0
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 55 17 0 0 10
DMWD-201 DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 61 378 23 23 0
DOK2-201 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 1 hippie 40 255 21 21 0
DUSP8-202 DUSP8 Q13202 Dual specificity protein phosphatase 8 chr11 Not Cancer Driver No 1 hippie 31 338 10 10 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 67 284 20 20 0
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EIF4A3-209 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 40 57 6 6 1
ELK4-202 ELK4 P28324 ETS domain-containing protein Elk-4 chr1 Census Yes 1 intact, hippie 35 240 22 22 0
ENST00000598884 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie 14 104 10 10 0
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 21 23 1 1 1
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FBP1-201 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 24 19 0 0 4
FBXO28-201 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 1 hippie, biogrid 28 230 15 15 1
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FGD5-201 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 hippie, biogrid 197 917 134 134 0
FHL2-211 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
FLNA-202 FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 314 1460 162 162 29
FN1-203 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 289 1249 137 137 8
GABARAPL1-201 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 10 10 1 1 0
GABARAPL2-201 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 4 2 1 1 0
GAK-201 GAK O14976 Cyclin-G-associated kinase chr4 Not Cancer Driver No 1 intact, hippie 110 592 57 57 0
GH1-201 GH1 P01241 Somatotropin chr17 Not Cancer Driver No 1 intact, hippie 41 24 7 7 14
GLI1-201 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 156 1018 138 138 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 21 10 0 0 0
GRN-201 GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 64 29 4 4 1
H2BC9-201 H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 30 79 10 10 0
HASPIN-201 HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 46 376 13 13 0
HCN1-201 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 1 intact 378 366 163 163 15
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
HEXA-201 HEXA P06865 Beta-hexosaminidase subunit alpha chr15 Not Cancer Driver No 1 hippie 48 5 1 1 39
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HOOK3-201 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 65 493 44 44 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 82 252 28 28 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
IKBKE-203 IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 90 76 10 10 0
IQGAP1-201 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 137 351 25 25 0
ITGA4-203 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 209 97 23 23 0
ITM2B-204 ITM2B Q9Y287 Integral membrane protein 2B chr13 Not Cancer Driver No 1 intact 15 12 0 0 1
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
JUP-203 JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 81 242 24 24 0
KCNK3-201 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 Not Cancer Driver No 1 intact 44 61 6 6 6
KIAA1671-201 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 1 hippie, biogrid 9 1760 9 9 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 771 7 2 2 22
L1TD1-201 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 91 543 72 72 0
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 39 353 28 28 0
LEO1-201 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 57 611 53 53 0
LIMA1-201 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 64 688 60 60 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MAGOH-202 MAGOH P61326 Protein mago nashi homolog chr1 Not Cancer Driver No 1 hippie 11 6 0 0 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 4 17 0 0 0
MAP3K3-202 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 48 356 27 27 0
MAPK14-201 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 22 25 0 0 0
MARK2-204 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 2 hippie, biogrid 84 445 52 52 0
MARK3-205 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie 64 376 38 38 1
MBTPS2-202 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 41 16 3 3 9
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 104 593 69 69 0
MCFD2-201 MCFD2 Q8NI22 Multiple coagulation factor deficiency protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 16 90 9 9 4
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 77 277 33 33 1
MDC1-201 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 175 1829 156 156 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MEPCE-201 MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 46 449 29 29 0
MINK1-202 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 86 742 42 42 0
MOSPD2-201 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 intact 39 143 10 10 0
MRPL20-201 MRPL20 Q9BYC9 Large ribosomal subunit protein bL20m chr1 Not Cancer Driver No 1 intact, hippie, biogrid 16 0 0 0 0
MTCL1-201 MTCL1 Q9Y4B5 Microtubule cross-linking factor 1 chr18 Not Cancer Driver No 1 hippie, biogrid 199 1695 169 169 0
MTPN-201 MTPN P58546 Myotrophin chr7 Not Cancer Driver No 3 intact, hippie, biogrid 7 11 3 3 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYH11-201 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 244 1186 144 144 2
MYH9-201 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 247 1124 126 126 13
MYLK-202 MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1 intact, hippie, biogrid 267 965 144 144 3
MYO18A-203 MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 181 1246 112 112 0
MYO19-213 MYO19 Q96H55 Unconventional myosin-XIX chr17 Not Cancer Driver No 1 intact, hippie 80 147 11 11 0
MYO5B-201 MYO5B Q9ULV0 Unconventional myosin-Vb chr18 Not Cancer Driver No 1 hippie, biogrid 205 507 53 53 23
MYO5C-201 MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 138 395 31 31 0
NAPA-201 NAPA P54920 Alpha-soluble NSF attachment protein chr19 Not Cancer Driver No 1 hippie, biogrid 19 11 0 0 0
NCBP1-202 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact 66 89 7 7 0
NDN-201 NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 119 117 40 40 0
NDUFA7-201 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie 14 104 10 10 0
NFX1-203 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 89 492 28 28 0
NIN-202 NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 177 1402 121 121 2
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 193 891 140 140 0
NMRAL1-201 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 28 14 2 2 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUDCD2-201 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 10 40 5 5 0
NUPR1-201 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OCRL-202 OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 105 126 18 18 36
PAFAH1B1-202 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 biogrid 37 83 11 11 7
PAN2-221 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 104 78 8 8 0
PAPSS1-201 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 Not Cancer Driver No 1 hippie 66 83 9 9 0
PAXIP1-201 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 41 462 1 1 0
PCID2-202 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 34 13 2 2 0
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
PDLIM7-202 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 30 247 14 14 0
PER2-201 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie 118 783 72 72 1
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PIM3-201 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 22 9 0 0 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHO1-201 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 2 hippie, biogrid 44 343 36 36 0
PLEKHO2-201 PLEKHO2 Q8TD55 Pleckstrin homology domain-containing family O member 2 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 48 404 46 46 0
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 31 27 6 6 0
PPP1CB-202 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 33 25 4 4 4
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 intact, hippie 19 23 3 3 0
PPP1R9A-207 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 159 891 128 128 0
PPP2R2B-203 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie 66 76 11 11 1
PPT1-219 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 27 0 0 0 22
PRC1-202 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 44 236 17 17 0
PRNP-201 PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 28 117 8 8 19
PSMC1-201 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 biogrid 29 165 8 8 0
PSME3-210 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 16 25 5 5 0
PTN-201 PTN P21246 Pleiotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 27 51 6 6 0
RAD18-201 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 42 330 31 31 0
RAF1-201 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact 64 169 30 30 18
RASA1-201 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 118 181 19 19 3
RBM39-201 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 53 228 16 16 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 114 798 81 81 0
RC3H2-202 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 99 704 62 62 0
RCSD1-202 RCSD1 Q6JBY9 CapZ-interacting protein chr1 Not Cancer Driver No 2 hippie, biogrid 56 418 56 56 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RHOBTB2-201 RHOBTB2 Q9BYZ6 Rho-related BTB domain-containing protein 2 chr8 Not Cancer Driver No 1 hippie 54 131 10 10 5
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 16 10 0 0 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 15 11 0 0 0
RHOV-201 RHOV Q96L33 Rho-related GTP-binding protein RhoV chr15 Not Cancer Driver No 1 hippie 17 48 5 5 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 64 420 31 31 0
RIPK3-201 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 47 295 27 27 0
RND3-201 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 23 70 7 7 0
RNF138-202 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 32 35 5 5 0
RNF169-201 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 Not Cancer Driver No 1 hippie 41 638 40 40 0
RPAP3-201 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 34 334 20 20 0
RPGRIP1L-212 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 127 587 73 73 8
RPL36A-209 RPL36A P83881 Large ribosomal subunit protein eL42 chrX Not Cancer Driver No 1 biogrid 14 64 11 11 0
RPP14-201 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
SCARB2-201 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 46 13 3 3 1
SERPINA5-201 SERPINA5 P05154 Plasma serine protease inhibitor chr14 Not Cancer Driver No 1 hippie 84 25 16 16 0
SH3BGRL-201 SH3BGRL O75368 Adapter SH3BGRL chrX Not Cancer Driver No 1 intact, hippie 17 51 7 7 0
SH3BP1-210 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 50 438 33 33 0
SH3KBP1-205 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 4 intact, hippie, biogrid 65 532 49 49 0
SIRPA-202 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie 60 282 41 41 0
SIRT6-202 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 24 165 6 6 0
SLC25A1-201 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 hippie 17 34 1 1 15
SOX2-201 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 32 312 32 32 0
SP1-201 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 67 601 53 53 0
STAP1-201 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 46 105 12 12 0
SVIL-201 SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie, biogrid 245 1434 151 151 0
SYNPO-202 SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 70 923 69 69 0
TAF2-201 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 biogrid 83 242 21 21 1
TBCK-204 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 83 89 5 5 2
TES-201 TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 28 100 6 6 0
TMOD3-201 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 1 hippie, biogrid 27 190 15 15 0
TNKS1BP1-201 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 167 1726 166 166 0
TOMM40-203 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 15 98 0 0 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TP53BP1-201 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 159 1638 131 131 0
TPM2-209 TPM2 P07951 Tropomyosin beta chain chr9 Not Cancer Driver No 1 hippie, biogrid 24 232 21 21 20
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 51 62 5 5 0
TRIM14-201 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 28 94 4 4 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 89 493 42 42 3
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact 45 52 6 6 6
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 51 54 6 6 10
TWF1-201 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 25 52 1 1 0
TWF2-201 TWF2 Q6IBS0 Twinfilin-2 chr3 Not Cancer Driver No 1 hippie, biogrid 28 59 8 8 0
U2AF2-201 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 61 191 24 24 0
UBA2-201 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 biogrid 62 221 22 22 4
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 25 32 4 4 0
UBE2Q2-201 UBE2Q2 Q8WVN8 Ubiquitin-conjugating enzyme E2 Q2 chr15 Not Cancer Driver No 1 hippie 28 122 8 8 0
UBL7-202 UBL7 Q96S82 Ubiquitin-like protein 7 chr15 Not Cancer Driver No 1 hippie, biogrid 25 192 18 18 0
UBR5-207 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 260 1299 135 135 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
UIMC1-212 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 1 hippie, biogrid 38 610 31 31 0
USP14-201 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 38 86 4 4 0
VCAM1-201 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 152 110 21 21 0
VCL-201 VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie 83 680 60 60 2
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 85 117 15 15 84
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VMP1-201 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 39 68 7 7 0
VPS26A-201 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 intact, hippie 21 45 3 3 0
WASHC2A-201 WASHC2A Q641Q2 WASH complex subunit 2A chr10 Not Cancer Driver No 1 hippie 44 1224 38 38 0
WASHC2C-209 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 Not Cancer Driver No 1 hippie 65 1225 64 64 0
WASHC3-201 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 18 100 5 5 0
WASHC4-202 WASHC4 Q2M389 WASH complex subunit 4 chr12 Not Cancer Driver No 1 hippie 93 49 2 2 1
WASHC5-201 WASHC5 Q12768 WASH complex subunit 5 chr8 Not Cancer Driver No 1 intact, hippie 123 23 6 6 6
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 87 423 46 46 0
XRN2-201 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 Not Cancer Driver No 1 biogrid 91 428 48 48 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact 21 78 4 4 3
ZBTB18-206 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 62 236 18 18 0
ZNF574-202 ZNF574 Q6ZN55 Zinc finger protein 574 chr19 Not Cancer Driver No 1 biogrid 86 411 40 40 0