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CASP9-201 ,CASP9 ,P55211
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 70
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 106 609 53 53 2
ACTR3-201 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie 24 16 2 2 0
AKAP12-204 AKAP12 Q02952 A-kinase anchor protein 12 chr6 Not Cancer Driver No 1 hippie 156 1780 156 156 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 99 158 19 19 4
APAF1-210 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 Not Cancer Driver No 1 hippie 91 17 1 1 0
ARNT-202 ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 61 511 47 47 0
ATG7-226 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 Compendium Yes 1 hippie 60 54 6 6 6
BAX-202 BAX Q07812 Apoptosis regulator BAX chr19 Census Yes 1 hippie 24 39 2 2 0
BCL10-202 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 Census, Compendium Yes 1 hippie 20 153 14 14 0
BCL2L1-201 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 22 55 2 2 0
BCL2L10-201 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 Not Cancer Driver No 1 hippie 6 35 0 0 0
BICD2-202 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 83 546 51 51 10
BIRC2-201 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 49 85 7 7 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BIRC5-202 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 Not Cancer Driver No 1 hippie 16 51 4 4 0
BIRC6-201 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 Census, Compendium Yes 1 hippie 468 1314 124 124 0
BIRC7-201 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 Not Cancer Driver No 1 hippie 45 138 18 18 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 31 213 13 13 0
CAPN2-201 CAPN2 P17655 Calpain-2 catalytic subunit chr1 Not Cancer Driver No 1 hippie 52 46 6 6 0
CARD8-231 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 41 130 5 5 1
CASP10-201 CASP10 Q92851 Caspase-10 chr2 Not Cancer Driver No 1 hippie 37 126 9 9 3
CASP3-201 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 19 64 1 1 0
CASP7-203 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 28 75 7 7 0
CASP8-218 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 116 106 11 11 1
CASP9-201 CASP9 P55211 Caspase-9 chr1 Census Yes 1 hippie 26 71 7 7 0
CFL1-201 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie 17 4 0 0 0
CRYAB-217 CRYAB P02511 Alpha-crystallin B chain chr11 Not Cancer Driver No 1 hippie 17 59 7 7 5
CYCS-201 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 hippie 10 20 2 2 1
DCC-202 DCC P43146 Netrin receptor DCC chr18 Census, Compendium Yes 1 hippie 447 632 192 192 2
DIABLO-207 DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie 20 54 2 2 1
DSP-201 DSP P15924 Desmoplakin chr6 Not Cancer Driver No 1 hippie 354 1127 146 146 6
EIF4A1-201 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 1 hippie 32 35 4 4 0
GMEB1-201 GMEB1 Q9Y692 Glucocorticoid modulatory element-binding protein 1 chr1 Not Cancer Driver No 1 hippie 49 312 27 27 0
GZMB-201 GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 31 103 13 13 0
HECTD3-202 HECTD3 Q5T447 E3 ubiquitin-protein ligase HECTD3 chr1 Not Cancer Driver No 1 hippie 66 55 3 3 0
HIP1-201 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie 118 514 60 60 0
HMGB1-203 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 hippie 10 202 7 7 0
HMGB1P1-201 HMGB1P1 B2RPK0 Putative high mobility group protein B1-like 1 chr20 Not Cancer Driver No 1 hippie 0 202 0 0 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HPRT1-201 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX Not Cancer Driver No 1 hippie 19 3 0 0 57
HSD17B4-211 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 Not Cancer Driver No 1 hippie 72 83 11 11 4
HSPB1-201 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 19
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 45 83 1 1 2
HTRA4-201 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 42 15 0 0 0
ILK-201 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 30 72 7 7 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 78 85 10 10 0
MAP2K1-201 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie 83 96 22 22 5
MAP2K2-201 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 Census Yes 1 hippie 45 107 13 13 3
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 52 2 0 0 6
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MSTO1-201 MSTO1 Q9BUK6 Protein misato homolog 1 chr1 Not Cancer Driver No 1 hippie 30 84 3 3 1
NAIP-208 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 Not Cancer Driver No 1 hippie 29 67 4 4 0
NLRP1-208 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 Not Cancer Driver No 1 hippie 169 341 45 45 6
NOD1-201 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 98 39 4 4 0
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 41 80 13 13 1
PRKCZ-201 PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 hippie 47 117 11 11 0
PTCH1-201 PTCH1 Q13635 Protein patched homolog 1 chr9 Census, Compendium Yes 1 hippie 156 383 39 39 17
RB1-201 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 89 282 26 26 21
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 26 203 15 15 1
RNF34-201 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 Not Cancer Driver No 1 hippie 17 112 4 4 0
RNPEP-201 RNPEP Q9H4A4 Aminopeptidase B chr1 Not Cancer Driver No 1 hippie 48 86 2 2 0
SLFN11-214 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 125 34 7 7 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 41 271 24 24 30
SRF-201 SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 hippie 30 443 29 29 0
TRIM72-201 TRIM72 Q6ZMU5 Tripartite motif-containing protein 72 chr16 Not Cancer Driver No 1 hippie 43 69 11 11 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 67 316 45 45 1
XIAP-202 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 61 55 2 2 0