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CDC7-201 ,CDC7 ,O00311
  • Number of Interaction partner in intact: 47
  • Number of Interaction partner in biogrid: 18
  • Number of Interaction partner in hippie: 88
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARF1-201 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 intact 22 4 2 2 2
BANP-201 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 intact, hippie 44 315 27 27 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 intact, hippie 31 213 13 13 0
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CDC7-201 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 2 intact, hippie 49 187 17 17 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CDK4-201 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 1 intact, hippie 38 52 3 3 2
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 intact, hippie 40 34 2 2 0
CDKN1A-201 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 intact, hippie 38 121 25 25 0
CDKN2A-201 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 intact, hippie 151 83 81 81 30
CENPJ-201 CENPJ Q9HC77 Centromere protein J chr13 Not Cancer Driver No 1 hippie 120 1180 108 108 1
CHAF1A-201 CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 Not Cancer Driver No 1 intact, hippie 66 768 48 48 0
CLSPN-202 CLSPN Q9HAW4 Claspin chr1 Not Cancer Driver No 1 hippie 92 1287 89 89 0
COLGALT1-201 COLGALT1 Q8NBJ5 Procollagen galactosyltransferase 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 74 116 8 8 3
DBF4-201 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 Not Cancer Driver No 12 intact, hippie, biogrid 48 334 18 18 0
DBF4B-201 DBF4B Q8NFT6 Protein DBF4 homolog B chr17 Not Cancer Driver No 4 intact, hippie, biogrid 50 312 17 17 0
DIAPH1-201 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 Not Cancer Driver No 1 hippie 46 692 20 20 1
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 106 520 65 65 0
DTD1-201 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 Not Cancer Driver No 1 hippie 37 93 22 22 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ENST00000480336 ZBTB8B Q8NAP8 Zinc finger and BTB domain-containing protein 8B chr1 Not Cancer Driver No 1 intact, hippie 14 177 7 7 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 Not Cancer Driver No 1 intact, hippie 63 312 40 40 0
GMEB2-203 GMEB2 Q9UKD1 Glucocorticoid modulatory element-binding protein 2 chr20 Not Cancer Driver No 1 hippie 70 277 34 34 0
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 84 859 71 71 0
GOLGA6A-201 GOLGA6A Q9NYA3 Golgin subfamily A member 6A chr15 Not Cancer Driver No 1 intact, hippie 41 636 35 35 0
GPT-202 GPT P24298 Alanine aminotransferase 1 chr8 Not Cancer Driver No 1 intact, hippie 43 51 5 5 0
GRHPR-201 GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie 29 36 3 3 0
HADHB-201 HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 54 41 9 9 12
HDGFL2-208 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 26 622 26 26 0
HHIPL1-201 HHIPL1 Q96JK4 HHIP-like protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 57 162 10 10 0
HMBOX1-201 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 36 319 28 28 0
HMGA2-204 HMGA2 P52926 High mobility group protein HMGI-C chr12 Census Yes 1 hippie, biogrid 9 109 9 9 0
HOMEZ-201 HOMEZ Q8IX15 Homeobox and leucine zipper protein Homez chr14 Not Cancer Driver No 1 hippie 50 401 40 40 0
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 261 668 51 51 2
ICE1-201 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 Not Cancer Driver No 1 intact, hippie 257 1675 191 191 0
IFT122-203 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 1 hippie 108 54 5 5 5
IGF2BP2-202 IGF2BP2 Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 chr3 Census Yes 1 hippie, biogrid 51 237 23 23 0
IKZF1-201 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 intact, hippie 106 328 72 72 4
IKZF3-203 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 89 286 52 52 1
IKZF4-203 IKZF4 Q9H2S9 Zinc finger protein Eos chr12 Not Cancer Driver No 1 intact, hippie 50 417 43 43 0
IL13RA2-201 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX Not Cancer Driver No 1 hippie, biogrid 56 0 0 0 0
IMMT-204 IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 75 402 39 39 0
KMT2E-202 KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 Not Cancer Driver No 1 hippie 177 1615 158 158 4
LZTS1-202 LZTS1 Q9Y250 Leucine zipper putative tumor suppressor 1 chr8 Not Cancer Driver No 1 intact, hippie 90 471 69 69 0
MAPK6-201 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 52 166 13 13 0
MCM10-206 MCM10 Q7L590 Protein MCM10 homolog chr10 Not Cancer Driver No 1 intact, hippie 111 538 75 75 1
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 2 intact, hippie 77 277 33 33 1
MCM3-205 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 2 intact, hippie 58 310 28 28 0
MCM4-222 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 hippie 93 215 29 29 0
MCM5-201 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 68 110 15 15 1
MCM6-201 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 1 hippie 78 122 11 11 0
MCM7-201 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 hippie 75 128 16 16 0
MCMBP-201 MCMBP Q9BTE3 Mini-chromosome maintenance complex-binding protein chr10 Not Cancer Driver No 2 intact, hippie 45 136 12 12 0
MEOX2-201 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 59 275 53 53 0
MRPL2-202 MRPL2 Q5T653 Large ribosomal subunit protein uL2m chr6 Not Cancer Driver No 1 intact, hippie, biogrid 32 132 12 12 0
MTUS2-206 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 intact, hippie 308 1216 290 290 0
NDUFB2-201 NDUFB2 O95178 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial chr7 Not Cancer Driver No 1 hippie 10 26 3 3 0
NUP210-201 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie, biogrid 213 157 14 14 0
ORC1-202 ORC1 Q13415 Origin recognition complex subunit 1 chr1 Not Cancer Driver No 1 hippie 72 340 30 30 5
ORC5-201 ORC5 O43913 Origin recognition complex subunit 5 chr7 Not Cancer Driver No 1 intact, hippie 27 16 2 2 0
ORC6-201 ORC6 Q9Y5N6 Origin recognition complex subunit 6 chr16 Not Cancer Driver No 2 intact, hippie 20 69 9 9 1
PAF1-201 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 36 378 23 23 0
PGK1-201 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie 44 40 3 3 9
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLOD1-201 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 12 0 0 5
PRC1-202 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 44 236 17 17 0
PSIP1-203 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 Census, Compendium Yes 1 hippie 45 482 42 42 0
RACK1-227 RACK1 P63244 Small ribosomal subunit protein RACK1 chr5 Not Cancer Driver No 1 intact, hippie 27 13 0 0 0
RAD18-201 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 42 330 31 31 0
RBFOX1-211 RBFOX1 Q9NWB1 RNA binding protein fox-1 homolog 1 chr16 Compendium Yes 1 biogrid 139 182 72 72 0
RBFOX2-210 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 1 biogrid 31 163 18 18 0
RBFOX3-203 RBFOX3 A6NFN3 RNA binding protein fox-1 homolog 3 chr17 Not Cancer Driver No 1 biogrid 9 172 3 3 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 99 232 31 31 3
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 intact 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 intact 48 26 3 3 0
SERTAD2-201 SERTAD2 Q14140 SERTA domain-containing protein 2 chr2 Not Cancer Driver No 1 intact, hippie 30 258 25 25 0
SHLD2-201 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 Not Cancer Driver No 1 hippie 51 156 5 5 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SOCS6-201 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 Not Cancer Driver No 1 hippie 65 302 44 44 0
STAM2-201 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 intact, hippie 49 292 25 25 0
TMBIM6-201 TMBIM6 P55061 Bax inhibitor 1 chr12 Not Cancer Driver No 1 hippie 12 3 0 0 0
TOB1-202 TOB1 P50616 Protein Tob1 chr17 Not Cancer Driver No 1 hippie 27 214 15 15 0
TRIM27-202 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 46 87 9 9 0
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 89 493 42 42 3
TSNAXIP1-201 TSNAXIP1 Q2TAA8 Translin-associated factor X-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 67 238 25 25 0
TSPY10-201 TSPY10 P0CW01 Testis-specific Y-encoded protein 10 chrY Not Cancer Driver No 1 intact, hippie 0 113 0 0 0
TSPY3-203 TSPY10 P0CW01 Testis-specific Y-encoded protein 10 chrY Not Cancer Driver No 1 intact, hippie 0 113 0 0 0
TSPY4-202 TSPY4 P0CV99 Testis-specific Y-encoded protein 4 chrY Not Cancer Driver No 1 hippie 0 109 0 0 0
TWF1-201 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 25 52 1 1 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
ZBTB10-204 ZBTB10 Q96DT7 Zinc finger and BTB domain-containing protein 10 chr8 Not Cancer Driver No 1 intact, hippie 39 531 24 24 0
ZBTB26-202 ZBTB26 Q9HCK0 Zinc finger and BTB domain-containing protein 26 chr9 Not Cancer Driver No 1 intact, hippie 30 137 10 10 0
ZBTB8B-201 ZBTB8B Q8NAP8 Zinc finger and BTB domain-containing protein 8B chr1 Not Cancer Driver No 1 intact, hippie 16 204 10 10 0