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CDK18-203 ,CDK18 ,Q07002
  • Number of Interaction partner in intact: 79
  • Number of Interaction partner in biogrid: 39
  • Number of Interaction partner in hippie: 130
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAA2-201 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 32 52 1 1 0
ACKR2-201 ACKR2 O00590 Atypical chemokine receptor 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 51 25 4 4 0
AK8-201 AK8 Q96MA6 Adenylate kinase 8 chr9 Not Cancer Driver No 1 intact, hippie 55 54 7 7 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
BAG6-237 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 2 intact, hippie 73 856 59 59 0
BLZF1-203 BLZF1 Q9H2G9 Golgin-45 chr1 Not Cancer Driver No 1 intact, hippie 37 220 17 17 0
CA4-201 CA4 P22748 Carbonic anhydrase 4 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 42 81 11 11 4
CBY1-201 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 2 intact, hippie 9 98 7 7 0
CBY2-201 CBY2 Q8NA61 Protein chibby homolog 2 chr13 Not Cancer Driver No 1 intact 73 343 56 56 0
CCDC102B-201 CCDC102B Q68D86 Coiled-coil domain-containing protein 102B chr18 Not Cancer Driver No 1 hippie 98 337 71 71 0
CCDC125-202 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 Not Cancer Driver No 1 intact, hippie 34 262 16 16 0
CCDC85B-201 CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 Not Cancer Driver No 1 intact, hippie 3 81 2 2 0
CCDC88B-202 CCDC88B A6NC98 Coiled-coil domain-containing protein 88B chr11 Not Cancer Driver No 1 intact, hippie 123 1158 98 98 0
CCND3-203 CCND3 P30281 G1/S-specific cyclin-D3 chr6 Census, Compendium Yes 1 intact, hippie 24 46 7 7 0
CCNDBP1-201 CCNDBP1 O95273 Cyclin-D1-binding protein 1 chr15 Not Cancer Driver No 1 hippie 22 63 5 5 0
CCNK-201 CCNK O75909 Cyclin-K chr14 Not Cancer Driver No 2 intact, hippie 27 347 9 9 1
CCT2-201 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 intact, hippie, biogrid 51 46 4 4 0
CCT3-201 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact, hippie, biogrid 53 95 11 11 0
CCT4-201 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 intact, hippie, biogrid 37 93 1 1 0
CCT5-201 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 intact, hippie, biogrid 65 72 8 8 1
CCT6A-201 CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 intact, hippie, biogrid 54 5 1 1 0
CCT7-201 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 intact, hippie, biogrid 45 36 3 3 0
CCT8-201 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 intact, hippie, biogrid 28 36 0 0 0
CDC37-201 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie, biogrid 43 214 29 29 0
CDK1-203 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 26 1 0 0 0
CDK15-210 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 49 36 3 3 0
CDK16-202 CDK16 Q00536 Cyclin-dependent kinase 16 chrX Not Cancer Driver No 3 hippie, biogrid 42 140 21 21 0
CDK17-201 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 Not Cancer Driver No 1 hippie, biogrid 49 200 19 19 0
CDK18-203 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 hippie 47 132 12 12 0
CDK5-204 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 intact, hippie 38 5 0 0 0
CDKN1A-201 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie, biogrid 38 121 25 25 0
CDR2-201 CDR2 Q01850 Cerebellar degeneration-related protein 2 chr16 Not Cancer Driver No 1 hippie 40 287 20 20 0
CEP76-201 CEP76 Q8TAP6 Centrosomal protein of 76 kDa chr18 Not Cancer Driver No 1 intact, hippie 41 97 4 4 0
CHTOP-204 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 Not Cancer Driver No 1 hippie, biogrid 23 244 21 21 0
COL1A1-201 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie, biogrid 36 1213 10 10 140
COL1A2-201 COL1A2 P08123 Collagen alpha-2(I) chain chr7 Not Cancer Driver No 1 hippie, biogrid 84 1160 50 50 81
CTSB-202 CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie 36 7 2 2 0
DNLZ-201 DNLZ Q5SXM8 DNL-type zinc finger protein chr9 Not Cancer Driver No 3 intact, hippie, biogrid 12 73 4 4 0
DPF2-205 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 49 179 21 21 5
DUSP7-202 DUSP7 Q16829 Dual specificity protein phosphatase 7 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 31 139 5 5 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
EEF2-201 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 intact, hippie 86 79 9 9 1
EIF3I-224 EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 intact, hippie 38 46 5 5 0
ENG-202 ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 47 114 11 11 29
EYA2-202 EYA2 O00167 Eyes absent homolog 2 chr20 Not Cancer Driver No 1 intact, hippie 89 204 44 44 0
FAAP100-201 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 intact, hippie 72 209 16 16 0
FCHSD2-204 FCHSD2 O94868 F-BAR and double SH3 domains protein 2 chr11 Not Cancer Driver No 1 hippie 41 392 21 21 0
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 2 hippie, biogrid 67 52 6 6 0
FKBP5-201 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 47 150 15 15 0
FSD2-201 FSD2 A1L4K1 Fibronectin type III and SPRY domain-containing protein 2 chr15 Not Cancer Driver No 1 hippie 82 300 45 45 0
FUBP3-201 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 49 354 38 38 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 Not Cancer Driver No 2 intact, hippie 63 312 40 40 0
GNB4-201 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 intact, hippie 35 28 0 0 2
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 2 intact, hippie 84 859 71 71 0
GOLGA6L9-202 GOLGA6L9 A6NEM1 Golgin subfamily A member 6-like protein 9 chr15 Not Cancer Driver No 1 intact, hippie 0 355 0 0 0
GORASP2-201 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 intact, hippie 42 288 24 24 0
HAP1-201 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie 56 463 37 37 0
HEXIM1-201 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 35 354 35 35 0
HMBOX1-201 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 36 319 28 28 0
HNRNPUL2-201 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 56 419 29 29 0
HNRNPUL2-BSCL2-201 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 56 421 29 29 0
HOMER3-202 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 Not Cancer Driver No 1 intact, hippie 14 254 7 7 0
HOOK2-202 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact, hippie 70 489 49 49 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 4 hippie, biogrid 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie, biogrid 70 255 29 29 0
IKZF3-203 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 89 286 52 52 1
INCA1-205 INCA1 Q0VD86 Protein INCA1 chr17 Not Cancer Driver No 1 intact, hippie 14 196 11 11 0
KANK2-201 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 88 534 59 59 3
KATNAL1-201 KATNAL1 Q9BW62 Katanin p60 ATPase-containing subunit A-like 1 chr13 Not Cancer Driver No 1 hippie 29 182 12 12 0
KIFC3-201 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 intact, hippie 60 488 34 34 0
KRT15-201 KRT15 P19012 Keratin, type I cytoskeletal 15 chr17 Not Cancer Driver No 1 intact, hippie 66 193 17 17 0
KRT16-201 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 intact, hippie 42 153 16 16 11
KRT31-201 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 78 64 9 9 0
KRT34-201 KRT34 O76011 Keratin, type I cuticular Ha4 chr17 Not Cancer Driver No 1 hippie 76 49 14 14 0
KRT40-201 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 intact, hippie 50 7 2 2 0
KRT75-201 KRT75 O95678 Keratin, type II cytoskeletal 75 chr12 Not Cancer Driver No 1 intact, hippie 78 145 23 23 1
KRT86-202 KRT86 O43790 Keratin, type II cuticular Hb6 chr12 Not Cancer Driver No 1 intact 39 28 1 1 5
LARP4B-201 LARP4B Q92615 La-related protein 4B chr10 Census Yes 1 hippie 92 522 66 66 0
LARP7-201 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 39 353 28 28 0
LZTS2-205 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 63 511 51 51 0
MAD1L1-201 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie 82 526 55 55 0
MAGED2-206 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie 72 328 38 38 1
MASTL-202 MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 Not Cancer Driver No 1 hippie 68 393 35 35 0
MID2-201 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX Not Cancer Driver No 1 hippie 81 96 19 19 1
MIPOL1-216 MIPOL1 Q8TD10 Mirror-image polydactyly gene 1 protein chr14 Not Cancer Driver No 1 intact, hippie 42 274 27 27 0
MTA2-201 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 59 283 25 25 0
MTR-202 MTR Q99707 Methionine synthase chr1 Not Cancer Driver No 1 hippie 116 104 10 10 2
MTUS2-206 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 2 intact, hippie 308 1216 290 290 0
NSRP1-201 NSRP1 Q9H0G5 Nuclear speckle splicing regulatory protein 1 chr17 Not Cancer Driver No 1 intact, hippie 43 524 41 41 0
NTPCR-202 NTPCR Q9BSD7 Cancer-related nucleoside-triphosphatase chr1 Not Cancer Driver No 1 hippie 20 31 1 1 0
NUTM1-201 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 hippie 156 975 137 137 0
P3H1-202 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 Not Cancer Driver No 1 intact, hippie 61 178 11 11 0
PIBF1-201 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 1 intact, hippie 66 420 30 30 3
PNMA1-201 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 Not Cancer Driver No 1 intact, hippie 32 56 7 7 0
PPFIA1-201 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie 118 865 96 96 0
PPP2CB-201 PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 1 intact, hippie 27 12 0 0 0
PPP5C-201 PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 58 73 10 10 0
PRKACA-201 PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie, biogrid 49 24 0 0 2
RAB3IP-212 RAB3IP Q96QF0 Rab-3A-interacting protein chr12 Not Cancer Driver No 1 hippie 70 228 31 31 0
RABEP1-202 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 Census, Compendium Yes 1 hippie 47 520 31 31 0
RALY-201 RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 hippie, biogrid 46 187 22 22 0
RBM4-201 RBM4 Q9BWF3 RNA-binding protein 4 chr11 Not Cancer Driver No 1 intact, hippie 29 129 9 9 0
REL-201 REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 53 365 35 35 0
RPL37A-210 RPL37A P61513 Large ribosomal subunit protein eL43 chr2 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
S100B-201 S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie, biogrid 8 14 0 0 0
SEC23A-201 SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 intact, hippie 66 73 5 5 1
SEC24D-201 SEC24D O94855 Protein transport protein Sec24D chr4 Not Cancer Driver No 1 hippie 91 322 36 36 2
SFXN2-201 SFXN2 Q96NB2 Sideroflexin-2 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 27 0 0 0 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 29 113 11 11 11
TCP1-201 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 34 55 7 7 0
TRAF1-201 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 intact, hippie 38 63 4 4 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 51 4 1 1 0
TRIM27-202 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 46 87 9 9 0
TRIM50-201 TRIM50 Q86XT4 E3 ubiquitin-protein ligase TRIM50 chr7 Not Cancer Driver No 1 intact, hippie 44 80 8 8 0
TRIM54-202 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 intact, hippie 47 98 11 11 0
TRPS1-201 TRPS1 Q9UHF7 Zinc finger transcription factor Trps1 chr8 Not Cancer Driver No 1 hippie 282 803 174 174 5
TSGA10-203 TSGA10 Q9BZW7 Testis-specific gene 10 protein chr2 Not Cancer Driver No 1 hippie 81 478 57 57 0
TTC23-203 TTC23 Q5W5X9 Tetratricopeptide repeat protein 23 chr15 Not Cancer Driver No 1 hippie 28 109 10 10 0
TTC29-201 TTC29 Q8NA56 Tetratricopeptide repeat protein 29 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 72 63 6 6 0
UBL4A-202 UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 2 intact, hippie 17 16 4 4 0
VPS28-201 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 Not Cancer Driver No 1 intact, hippie 17 31 5 5 0
VPS52-212 VPS52 Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog chr6 Not Cancer Driver No 1 hippie 63 36 4 4 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 4 intact, hippie, biogrid 19 110 3 3 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 2 intact, hippie 24 41 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 3 intact, hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 4 intact, hippie, biogrid 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 4 intact, hippie, biogrid 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 4 intact, hippie, biogrid 19 81 7 7 0
ZNF426-201 ZNF426 Q9BUY5 Zinc finger protein 426 chr19 Not Cancer Driver No 1 intact, hippie 43 24 4 4 0
ZNF438-205 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 94 614 71 71 0
ZNF774-201 ZNF774 Q6NX45 Zinc finger protein 774 chr15 Not Cancer Driver No 1 intact, hippie 43 237 24 24 0
ZRANB1-201 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 65 158 16 16 0