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CENPF-201 ,CENPF ,P49454
  • Number of Interaction partner in intact: 34
  • Number of Interaction partner in biogrid: 35
  • Number of Interaction partner in hippie: 95
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACER3-212 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 1
ACTC1-201 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 90 48 14 14 11
ALK-201 ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 2 intact, hippie, biogrid 233 577 79 79 12
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 101 771 75 75 2
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 23 104 9 9 0
ARRB2-201 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 39 122 19 19 0
ASF1A-201 ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 11 69 2 2 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 53 98 10 10 0
BRAP-202 BRAP Q7Z569 BRCA1-associated protein chr12 Not Cancer Driver No 1 hippie 54 193 16 16 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BRK1-201 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 hippie, biogrid 4 15 1 1 0
CBX4-201 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 intact, hippie 47 479 39 39 0
CCDC33-212 CCDC33 Q8N5R6 Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 2 hippie, biogrid 100 621 57 57 0
CCDC68-204 CCDC68 Q9H2F9 Coiled-coil domain-containing protein 68 chr18 Not Cancer Driver No 3 intact, hippie, biogrid 55 206 33 33 0
CDCA5-201 CDCA5 Q96FF9 Sororin chr11 Not Cancer Driver No 1 hippie 24 211 20 20 0
CDK1-203 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 26 1 0 0 0
CDK5RAP2-201 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 Not Cancer Driver No 1 intact 150 1142 92 92 0
CENPE-201 CENPE Q02224 Centromere-associated protein E chr4 Not Cancer Driver No 1 intact, hippie 242 1627 160 160 2
CENPF-201 CENPF P49454 Centromere protein F chr1 Not Cancer Driver No 1 hippie 272 2158 181 181 0
CENPU-201 CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 1 intact, hippie 23 302 19 19 0
CEP63-216 CEP63 Q96MT8 Centrosomal protein of 63 kDa chr3 Not Cancer Driver No 1 intact 77 508 50 50 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHMP2B-201 CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 Not Cancer Driver No 1 hippie 22 186 20 20 4
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 196 1020 116 116 3
COG6-204 COG6 Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 52 141 7 7 1
COPS6-201 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie 23 30 4 4 0
CTNNA1-201 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 90 268 25 25 4
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 54 102 2 2 0
CUL7-201 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 141 373 31 31 3
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 106 520 65 65 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ENST00000635511 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 0 0 0 0 0
ERP29-201 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 intact, hippie 24 34 4 4 0
ESAM-201 ESAM Q96AP7 Endothelial cell-selective adhesion molecule chr11 Not Cancer Driver No 1 intact, hippie, biogrid 37 155 22 22 0
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FAM167A-201 FAM167A Q96KS9 Protein FAM167A chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 116 16 16 0
FBXL5-201 FBXL5 Q9UKA1 F-box/LRR-repeat protein 5 chr4 Not Cancer Driver No 1 hippie, biogrid 50 71 4 4 0
FBXO38-202 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 94 441 33 33 1
FHIP1B-202 FHIP1B Q8N612 FHF complex subunit HOOK-interacting protein 1B chr11 Not Cancer Driver No 1 intact 97 420 42 42 0
FNTA-201 FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 Not Cancer Driver No 2 hippie, biogrid 29 92 9 9 0
FNTB-201 FNTB P49356 Protein farnesyltransferase subunit beta chr14 Not Cancer Driver No 4 hippie, biogrid 25 31 1 1 0
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 55 352 38 38 0
GOPC-202 GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 2 intact, hippie, biogrid 40 263 27 27 0
H1-1-201 H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 13 212 12 12 0
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 2 hippie, biogrid 5 301 4 4 21
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KPNA1-201 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie 48 122 16 16 0
KXD1-201 KXD1 Q9BQD3 KxDL motif-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 17 105 12 12 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MAGEA3-201 MAGEA3 P43357 Melanoma-associated antigen 3 chrX Not Cancer Driver No 1 hippie, biogrid 74 104 16 16 0
MAP7D2-202 MAP7D2 Q96T17 MAP7 domain-containing protein 2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 45 724 41 41 0
MAPRE3-201 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 24 120 11 11 0
MKI67-202 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 346 3213 343 343 0
MRFAP1L1-201 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 8 59 4 4 0
MTCH2-201 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 0
MTMR9-201 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 38 45 4 4 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MZT1-201 MZT1 Q08AG7 Mitotic-spindle organizing protein 1 chr13 Not Cancer Driver No 1 hippie 8 9 3 3 0
NANOG-201 NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 35 171 28 28 0
NDE1-201 NDE1 Q9NXR1 Nuclear distribution protein nudE homolog 1 chr16 Not Cancer Driver No 1 intact, hippie 34 316 33 33 0
NDEL1-201 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 Not Cancer Driver No 3 intact, hippie 23 203 13 13 0
NEURL4-202 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 145 753 83 83 0
NFKBIA-201 NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 intact, hippie 34 102 10 10 1
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 25 249 19 19 0
NQO2-205 NQO2 P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] chr6 Not Cancer Driver No 1 hippie, biogrid 20 10 1 1 0
NUP107-201 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 Not Cancer Driver No 1 intact, hippie 89 185 21 21 5
NUP133-201 NUP133 Q8WUM0 Nuclear pore complex protein Nup133 chr1 Not Cancer Driver No 1 intact, hippie 115 116 10 10 3
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
PAFAH1B1-202 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 hippie 37 83 11 11 7
PCLAF-201 PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 15 112 16 16 0
POLH-202 POLH Q9Y253 DNA polymerase eta chr6 Not Cancer Driver No 1 intact, hippie 49 291 15 15 10
PPP1R13B-201 PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 87 821 70 70 0
PRC1-202 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 44 236 17 17 0
RDX-219 RDX P35241 Radixin chr11 Not Cancer Driver No 1 hippie, biogrid 44 298 23 23 1
RHOT2-201 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 40 81 4 4 0
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 33 198 14 14 0
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RNF166-201 RNF166 Q96A37 E3 ubiquitin-protein ligase RNF166 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 15 24 2 2 0
RPL31-201 RPL31 P62899 Large ribosomal subunit protein eL31 chr2 Not Cancer Driver No 1 hippie 13 69 10 10 0
SETD2-202 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 Census, Compendium Yes 1 hippie 233 1949 144 144 4
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
SLC16A11-202 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 25 48 3 3 0
SLFN11-214 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 125 34 7 7 0
SNAP25-201 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 Not Cancer Driver No 1 hippie 46 178 38 38 1
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SVIL-201 SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 intact, hippie 245 1434 151 151 0
SYCE1-202 SYCE1 Q8N0S2 Synaptonemal complex central element protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 57 251 41 41 0
TCP10L-201 TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 23 216 23 23 0
TERF1-202 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 51 221 32 32 0
TERF2-201 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 26 361 15 15 0
TMA16-201 TMA16 Q96EY4 Translation machinery-associated protein 16 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 19 114 8 8 0
TOP3B-201 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie 76 151 11 11 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TSC22D1-203 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 intact, hippie 83 1028 74 74 0
TXLNA-202 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 hippie, biogrid 55 481 46 46 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WASF3-201 WASF3 Q9UPY6 Actin-binding protein WASF3 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 78 387 63 63 0