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CGN-201 ,CGN ,Q9P2M7
  • Number of Interaction partner in intact: 61
  • Number of Interaction partner in biogrid: 29
  • Number of Interaction partner in hippie: 134
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA2-201 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 2 hippie, biogrid 42 39 3 3 15
AFDN-211 AFDN P55196 Afadin chr6 Census Yes 1 hippie 162 1247 123 123 0
AGAP1-201 AGAP1 Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 121 407 59 59 0
AMOT-203 AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 103 911 85 85 0
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 101 771 75 75 2
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 116 443 38 38 144
ARHGEF11-201 ARHGEF11 O15085 Rho guanine nucleotide exchange factor 11 chr1 Not Cancer Driver No 1 hippie, biogrid 170 1038 113 113 0
ARHGEF2-203 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 Not Cancer Driver No 1 hippie 121 450 64 64 0
CAMSAP2-201 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 Not Cancer Driver No 1 hippie 128 1025 92 92 0
CAPZA2-201 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 21 19 0 0 0
CBY1-201 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 2 intact, hippie 9 98 7 7 0
CCDC102B-201 CCDC102B Q68D86 Coiled-coil domain-containing protein 102B chr18 Not Cancer Driver No 1 hippie, biogrid 98 337 71 71 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CDC25B-201 CDC25B P30305 M-phase inducer phosphatase 2 chr20 Not Cancer Driver No 1 hippie 61 329 33 33 0
CDC25C-201 CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 2 intact, hippie 48 226 19 19 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CDK16-202 CDK16 Q00536 Cyclin-dependent kinase 16 chrX Not Cancer Driver No 1 hippie 42 140 21 21 0
CDKL2-202 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 42 171 19 19 0
CEP135-201 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie, biogrid 93 693 52 52 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CRTC2-203 CRTC2 Q53ET0 CREB-regulated transcription coactivator 2 chr1 Not Cancer Driver No 1 hippie 73 676 69 69 0
CRTC3-201 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 Census Yes 2 intact, hippie 59 612 58 58 0
CSNK1A1-202 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 2 intact, hippie 34 46 2 2 0
CTNNA1-201 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 90 268 25 25 4
CWC25-202 CWC25 Q9NXE8 Pre-mRNA-splicing factor CWC25 homolog chr17 Not Cancer Driver No 2 intact, hippie 48 398 46 46 0
DAB2IP-203 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 Not Cancer Driver No 2 intact, hippie, biogrid 95 682 49 49 0
DBN1-202 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 63 512 56 56 0
DCLK1-202 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 1 hippie 148 253 49 49 0
DCP1B-201 DCP1B Q8IZD4 mRNA-decapping enzyme 1B chr12 Not Cancer Driver No 2 intact, hippie 53 406 40 40 0
DENND1A-203 DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 Not Cancer Driver No 1 hippie 98 591 63 63 0
DENND4A-201 DENND4A Q7Z401 C-myc promoter-binding protein chr15 Not Cancer Driver No 1 hippie 125 570 41 41 0
DENND4C-209 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 Not Cancer Driver No 2 intact, hippie 121 709 40 40 0
DLST-202 DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie, biogrid 33 192 23 23 1
EIF4E2-201 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 Not Cancer Driver No 2 intact, hippie 24 80 5 5 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
ERLEC1-201 ERLEC1 Q96DZ1 Endoplasmic reticulum lectin 1 chr2 Not Cancer Driver No 1 hippie, biogrid 43 135 12 12 0
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 69 92 10 10 1
EYA2-202 EYA2 O00167 Eyes absent homolog 2 chr20 Not Cancer Driver No 1 intact, hippie 89 204 44 44 0
F11R-202 F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie 42 72 12 12 0
FBXL13-201 FBXL13 Q8NEE6 F-box and leucine-rich repeat protein 13 chr7 Not Cancer Driver No 1 hippie 77 41 3 3 0
FGD6-201 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 Not Cancer Driver No 2 intact, hippie 141 809 79 79 0
GAB2-202 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 63 540 53 53 0
GIGYF1-207 GIGYF1 O75420 GRB10-interacting GYF protein 1 chr7 Not Cancer Driver No 1 hippie 111 860 94 94 0
GIGYF2-201 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 Not Cancer Driver No 1 hippie 73 1098 62 62 6
HDAC4-201 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 2 intact, hippie 145 751 95 95 3
HDAC5-213 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 93 720 61 61 0
HDAC7-209 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 hippie 70 571 43 43 0
HMGB1-203 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 intact, hippie 10 202 7 7 0
HOOK3-201 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 65 493 44 44 0
IFT57-201 IFT57 Q9NWB7 Intraflagellar transport protein 57 homolog chr3 Not Cancer Driver No 1 hippie 36 219 18 18 0
IL13-201 IL13 P35225 Interleukin-13 chr5 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
INPP5E-201 INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 Not Cancer Driver No 2 intact, hippie 32 273 9 9 15
IQGAP1-201 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 137 351 25 25 0
KCTD3-201 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 2 intact, hippie 90 326 39 39 0
KIF13B-206 KIF13B Q9NQT8 Kinesin-like protein KIF13B chr8 Not Cancer Driver No 1 hippie 131 970 56 56 0
KIF14-201 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 145 777 65 65 2
KIF1B-214 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 2 intact, hippie 187 634 82 82 1
KIF1C-201 KIF1C O43896 Kinesin-like protein KIF1C chr17 Not Cancer Driver No 2 intact, hippie 97 700 69 69 1
KIF20A-201 KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 64 341 32 32 1
KRT27-201 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 hippie, biogrid 60 144 20 20 0
KSR1-219 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 2 intact, hippie 88 408 46 46 0
L1TD1-201 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 91 543 72 72 0
LARP1-204 LARP1 Q6PKG0 La-related protein 1 chr5 Not Cancer Driver No 1 hippie 100 815 75 75 0
LATS1-207 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 2 hippie, biogrid 122 790 74 74 0
LATS2-201 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 101 690 57 57 0
LIMA1-201 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 64 688 60 60 0
LNX1-201 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 90 261 33 33 0
LPIN3-201 LPIN3 Q9BQK8 Phosphatidate phosphatase LPIN3 chr20 Not Cancer Driver No 2 intact, hippie 75 473 39 39 0
LRFN1-201 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 77 278 31 31 0
LZTS2-205 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 63 511 51 51 0
MAGI1-202 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 2 intact, hippie 173 1181 140 140 0
MAP3K21-203 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 2 intact, hippie 146 665 92 92 0
MAPKAP1-201 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 Not Cancer Driver No 1 hippie 57 173 17 17 0
MAST3-201 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 2 intact, hippie 133 785 77 77 5
MELK-201 MELK Q14680 Maternal embryonic leucine zipper kinase chr9 Not Cancer Driver No 1 hippie 51 164 18 18 0
MICALL1-201 MICALL1 Q8N3F8 MICAL-like protein 1 chr22 Not Cancer Driver No 2 intact, hippie 71 633 55 55 0
MTFR1L-203 MTFR1L Q9H019 Mitochondrial fission regulator 1-like chr1 Not Cancer Driver No 2 intact, hippie 18 111 8 8 0
MTMR10-201 MTMR10 Q9NXD2 Myotubularin-related protein 10 chr15 Not Cancer Driver No 1 hippie, biogrid 43 98 4 4 0
MYH11-201 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 244 1186 144 144 2
MYO18A-203 MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 181 1246 112 112 0
MYO5C-201 MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 138 395 31 31 0
NADK-201 NADK O95544 NAD kinase chr1 Not Cancer Driver No 1 hippie 46 91 8 8 0
NAV1-202 NAV1 Q8NEY1 Neuron navigator 1 chr1 Not Cancer Driver No 1 intact 170 1457 128 128 0
NF1-202 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 2 intact, hippie 285 406 36 36 75
NPRL2-201 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 hippie 24 10 2 2 1
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 44 244 18 18 1
OSBPL6-201 OSBPL6 Q9BZF3 Oxysterol-binding protein-related protein 6 chr2 Not Cancer Driver No 2 intact, hippie 118 368 55 55 0
PANK2-201 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 Not Cancer Driver No 2 intact, hippie 33 208 11 11 28
PHLDB2-204 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 Not Cancer Driver No 1 hippie 168 1037 130 130 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 46 99 8 8 24
PLEKHA7-202 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 3 intact, hippie 129 925 106 106 0
PPM1H-201 PPM1H Q9ULR3 Protein phosphatase 1H chr12 Not Cancer Driver No 1 hippie 60 141 25 25 0
PPP1R13B-201 PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 intact, hippie 87 821 70 70 0
PPP1R9A-207 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 159 891 128 128 0
PTPN13-202 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 2 intact, hippie 213 1235 110 110 0
PTPN14-201 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie 130 584 79 79 0
RAB11FIP2-201 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 Not Cancer Driver No 1 hippie 41 356 24 24 0
RALGPS2-204 RALGPS2 Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 chr1 Not Cancer Driver No 2 intact, hippie 67 184 17 17 0
RASAL2-203 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 2 intact, hippie 134 607 69 69 0
RPTOR-201 RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 149 242 18 18 0
RTKN-202 RTKN Q9BST9 Rhotekin chr2 Not Cancer Driver No 1 hippie 53 265 30 30 0
SASS6-201 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 61 332 26 26 1
SFN-201 SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 16 75 3 3 0
SH3PXD2A-203 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 111 802 86 86 0
SH3RF3-201 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 Not Cancer Driver No 1 hippie 78 566 45 45 0
SIPA1L1-211 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 2 intact, hippie 231 1176 166 166 0
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 34 163 10 10 0
SLC39A3-201 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
SRGAP2-203 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 1 hippie 98 543 57 57 0
SRSF12-201 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 Not Cancer Driver No 2 intact, hippie 24 205 20 20 0
STARD13-202 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 Not Cancer Driver No 1 hippie 140 497 60 60 0
STIL-202 STIL Q15468 SCL-interrupting locus protein chr1 Census, Compendium Yes 1 hippie, biogrid 106 735 64 64 1
SYDE1-201 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 2 intact, hippie 52 412 25 25 0
SYNPO-202 SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 70 923 69 69 0
TANC2-202 TANC2 Q9HCD6 Protein TANC2 chr17 Not Cancer Driver No 2 intact, hippie 175 1001 83 83 1
TBC1D1-201 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 Not Cancer Driver No 2 intact, hippie 90 459 36 36 0
TESK2-202 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 Not Cancer Driver No 2 intact, hippie 57 243 31 31 0
TIAM1-206 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 2 intact, hippie 263 813 147 147 0
TJP1-201 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 4 intact, hippie, biogrid 143 1350 113 113 0
TJP2-202 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 2 hippie, biogrid 104 916 80 80 1
TMEM147-201 TMEM147 Q9BVK8 BOS complex subunit TMEM147 chr19 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 3
TP53BP2-201 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 Not Cancer Driver No 1 intact, hippie 106 866 83 83 0
TPR-201 TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 215 1994 184 184 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
USP14-201 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 38 86 4 4 0
WEE1-202 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 2 intact, hippie 42 399 20 20 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 4 intact, hippie, biogrid 19 110 3 3 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 4 intact, hippie, biogrid 24 41 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 5 intact, hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 4 intact, hippie, biogrid 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 3 intact, hippie, biogrid 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 4 intact, hippie, biogrid 19 81 7 7 0
ZBTB21-201 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 2 intact, hippie 91 649 48 48 0
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZNF638-201 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 2 intact, hippie 173 1674 153 153 0