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CHRM3-211 ,CHRM3 ,P20309
  • Number of Interaction partner in intact: 47
  • Number of Interaction partner in biogrid: 50
  • Number of Interaction partner in hippie: 87
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ARF1-201 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie 22 4 2 2 2
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie 16 5 0 0 0
ARL10-201 ARL10 Q8N8L6 ADP-ribosylation factor-like protein 10 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 14 19 0 0 0
ATL2-201 ATL2 Q8NHH9 Atlastin-2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 40 78 4 4 0
ATP1A3-214 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 151 116 21 21 41
ATP1A4-201 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 147 121 21 21 0
BSG-201 BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie 38 123 16 16 0
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 12 115 10 10 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 Not Cancer Driver No 1 hippie 13 115 8 8 6
CAND2-203 CAND2 O75155 Cullin-associated NEDD8-dissociated protein 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 96 97 11 11 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 23 2 0 0 0
CCDC184-201 CCDC184 Q52MB2 Coiled-coil domain-containing protein 184 chr12 Not Cancer Driver No 1 intact, hippie 15 185 15 15 0
CD2BP2-201 CD2BP2 O95400 CD2 antigen cytoplasmic tail-binding protein 2 chr16 Not Cancer Driver No 1 intact, hippie 35 260 28 28 0
CERS6-201 CERS6 Q6ZMG9 Ceramide synthase 6 chr2 Not Cancer Driver No 1 hippie, biogrid 33 32 6 6 0
CHRM3-211 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 Not Cancer Driver No 1 intact, hippie 155 137 35 35 0
CHRM5-201 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 Not Cancer Driver No 1 intact, hippie 51 157 15 15 0
COMMD7-201 COMMD7 Q86VX2 COMM domain-containing protein 7 chr20 Not Cancer Driver No 1 intact, hippie 22 21 0 0 0
CSNK1A1-202 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 34 46 2 2 0
DCP2-201 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 intact, hippie, biogrid 40 167 21 21 0
DNAJA3-201 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 44 152 19 19 0
DYM-201 DYM Q7RTS9 Dymeclin chr18 Not Cancer Driver No 2 intact, hippie, biogrid 57 22 0 0 3
ENST00000644613 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 151 115 21 21 39
EXOC2-201 EXOC2 Q96KP1 Exocyst complex component 2 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 74 134 10 10 0
FAM241B-201 FAM241B Q96D05 Protein FAM241B chr10 Not Cancer Driver No 1 intact, hippie 21 53 10 10 0
FARP2-201 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 100 252 29 29 0
FASTKD1-204 FASTKD1 Q53R41 FAST kinase domain-containing protein 1, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 79 0 0 0 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 intact, hippie, biogrid 203 259 33 33 14
FTSJ1-202 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 2 intact, hippie, biogrid 31 89 8 8 0
GBF1-223 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 161 670 62 62 0
GNAQ-201 GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie 82 14 1 1 1
GNAS-214 GNAS Q5JWF2 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas chr20 Census, Compendium Yes 1 hippie 112 718 33 33 2
GPN3-201 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 13 19 0 0 0
GPRASP1-205 GPRASP1 Q5JY77 G-protein coupled receptor-associated sorting protein 1 chrX Not Cancer Driver No 1 hippie 150 919 97 97 0
GRK6-201 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie 43 68 8 8 0
GTPBP2-202 GTPBP2 Q9BX10 GTP-binding protein 2 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 45 91 5 5 0
GZMB-201 GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 31 103 13 13 0
HEATR3-201 HEATR3 Q7Z4Q2 HEAT repeat-containing protein 3 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 56 134 7 7 2
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HOOK2-202 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 70 489 49 49 0
IPO13-202 IPO13 O94829 Importin-13 chr1 Not Cancer Driver No 2 hippie, biogrid 74 42 5 5 0
IPO7-201 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie, biogrid 108 202 25 25 0
IPO9-201 IPO9 Q96P70 Importin-9 chr1 Not Cancer Driver No 2 hippie, biogrid 101 103 15 15 0
ITPRIPL1-204 ITPRIPL1 Q6GPH6 Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 chr2 Not Cancer Driver No 1 hippie, biogrid 47 39 3 3 0
JAKMIP1-201 JAKMIP1 Q96N16 Janus kinase and microtubule-interacting protein 1 chr4 Not Cancer Driver No 1 hippie 118 389 95 95 0
JPH1-201 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 102 422 67 67 0
LRP10-201 LRP10 Q7Z4F1 Low-density lipoprotein receptor-related protein 10 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 75 237 26 26 0
LTN1-201 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 Not Cancer Driver No 2 intact, hippie, biogrid 139 125 15 15 0
MAGED2-206 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie 72 328 38 38 1
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 39 298 24 24 0
NALCN-201 NALCN Q8IZF0 Sodium leak channel NALCN chr13 Not Cancer Driver No 1 intact, hippie 399 260 62 62 11
NARS2-201 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie, biogrid 48 22 2 2 3
NEK4-201 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 55 495 40 40 0
NOCT-201 NOCT Q9UK39 Nocturnin chr4 Not Cancer Driver No 1 intact, hippie 22 90 2 2 0
PBXIP1-202 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 69 606 60 60 0
PEX1-201 PEX1 O43933 Peroxisomal ATPase PEX1 chr7 Not Cancer Driver No 1 hippie, biogrid 98 304 22 22 17
PI4KA-201 PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 2 hippie, biogrid 198 142 10 10 7
PIGX-202 PIGX Q8TBF5 Phosphatidylinositol-glycan biosynthesis class X protein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 18 0 0 0 0
PIK3CB-214 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 Census, Compendium Yes 2 intact, hippie, biogrid 112 42 3 3 0
PIK3R3-201 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 42 149 17 17 0
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 2 hippie, biogrid 71 98 5 5 0
POM121C-206 POM121C A8CG34 Nuclear envelope pore membrane protein POM 121C chr7 Not Cancer Driver No 1 intact, hippie 63 1123 59 59 0
PPP1R9B-202 PPP1R9B Q96SB3 Neurabin-2 chr17 Not Cancer Driver No 1 hippie 37 698 27 27 0
PPP6R1-201 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 60 473 36 36 0
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie, biogrid 385 421 43 43 2
PTRH2-201 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 2 intact, hippie, biogrid 7 19 1 1 1
RAB5IF-203 RAB5IF Q9BUV8 GEL complex subunit OPTI chr20 Not Cancer Driver No 1 hippie 1 13 0 0 0
RANBP6-201 RANBP6 O60518 Ran-binding protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 99 46 3 3 0
RGS4-203 RGS4 P49798 Regulator of G-protein signaling 4 chr1 Not Cancer Driver No 1 intact, hippie 46 5 3 3 0
RGS7-205 RGS7 P49802 Regulator of G-protein signaling 7 chr1 Census, Compendium Yes 1 hippie 169 150 43 43 0
SEPTIN3-203 SEPTIN3 Q9UH03 Neuronal-specific septin-3 chr22 Not Cancer Driver No 1 intact 33 105 10 10 0
SET-204 SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 19 221 12 12 2
SGSM3-201 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 Not Cancer Driver No 1 intact, hippie 59 77 7 7 0
SLC4A7-201 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 2 hippie, biogrid 105 405 37 37 0
STARD3-201 STARD3 Q14849 StAR-related lipid transfer protein 3 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 45 34 4 4 0
STX18-201 STX18 Q9P2W9 Syntaxin-18 chr4 Not Cancer Driver No 2 hippie, biogrid 23 176 12 12 0
TAP1-201 TAP1 Q03518 Antigen peptide transporter 1 chr6 Not Cancer Driver No 1 hippie 52 42 2 2 0
TELO2-201 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 Not Cancer Driver No 1 intact, hippie, biogrid 82 155 15 15 5
TPM3-224 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 intact, hippie 17 230 13 13 18
TTI1-201 TTI1 O43156 TELO2-interacting protein 1 homolog chr20 Not Cancer Driver No 2 intact, hippie, biogrid 104 94 12 12 0
TUBA3C-201 TUBA3D P0DPH8 Tubulin alpha-3D chain chr13 Not Cancer Driver No 1 hippie 145 36 4 4 0
TUBA3D-201 TUBA3D P0DPH8 Tubulin alpha-3D chain chr2 Not Cancer Driver No 1 hippie 56 36 1 1 0
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 2 intact, hippie, biogrid 50 39 2 2 4
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie, biogrid 51 54 6 6 10
TUBB8-206 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 2 intact, hippie, biogrid 77 53 13 13 14
USP46-201 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 27 29 2 2 0
YIPF3-202 YIPF3 Q9GZM5 Protein YIPF3 chr6 Not Cancer Driver No 1 hippie 26 88 8 8 0
YIPF4-201 YIPF4 Q9BSR8 Protein YIPF4 chr2 Not Cancer Driver No 1 hippie, biogrid 17 22 0 0 0