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CLIC4-201 ,CLIC4 ,Q9Y696
  • Number of Interaction partner in intact: 11
  • Number of Interaction partner in biogrid: 87
  • Number of Interaction partner in hippie: 107
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACADS-201 ACADS P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 42 18 3 3 10
ACO2-201 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 77 172 16 16 5
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 96 43 5 5 4
ADA-201 ADA P00813 Adenosine deaminase chr20 Not Cancer Driver No 1 hippie, biogrid 43 45 9 9 22
ALDH4A1-202 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 48 47 8 8 1
ARCN1-201 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie, biogrid 39 194 22 22 0
BSG-201 BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 16 16 0
C1orf198-201 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 31 305 27 27 0
CDA-201 CDA P32320 Cytidine deaminase chr1 Not Cancer Driver No 1 hippie, biogrid 15 8 0 0 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 17 0 0 0 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CLEC4D-201 CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 52 18 3 3 0
CLIC1-208 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 28 27 4 4 0
CLIC2-202 CLIC2 O15247 Chloride intracellular channel protein 2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 29 58 4 4 1
CLIC5-201 CLIC5 Q9NZA1 Chloride intracellular channel protein 5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 47 206 21 21 0
CLIC6-202 CLIC6 Q96NY7 Chloride intracellular channel protein 6 chr21 Not Cancer Driver No 4 intact, hippie, biogrid 40 504 15 15 0
CLPP-201 CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 15 83 7 7 3
CMPK1-207 CMPK1 P30085 UMP-CMP kinase chr1 Not Cancer Driver No 1 hippie, biogrid 15 41 5 5 0
COA7-201 COA7 Q96BR5 Cytochrome c oxidase assembly factor 7 chr1 Not Cancer Driver No 1 hippie, biogrid 19 40 5 5 2
COASY-201 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie, biogrid 43 50 4 4 1
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 13 5 1 1 1
COX5A-201 COX5A P20674 Cytochrome c oxidase subunit 5A, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 17 14 4 4 1
CRKL-201 CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie, biogrid 24 160 17 17 0
CRYZ-201 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
CSK-201 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie, biogrid 37 18 1 1 0
CTSB-202 CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie, biogrid 36 7 2 2 0
CTSL-203 CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 36 34 5 5 0
DAG1-201 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 1 hippie, biogrid 71 486 43 43 4
DDAH1-201 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 20 45 1 1 0
DDAH2-212 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 14 96 4 4 0
DDB1-201 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 biogrid 98 50 8 8 3
DNAJC9-201 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 1 hippie, biogrid 17 126 8 8 0
DNM1-202 DNM1 Q05193 Dynamin-1 chr9 Not Cancer Driver No 1 hippie 75 280 19 19 4
ENO1-201 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie, biogrid 37 21 2 2 0
ENST00000442788 PSMA2 P25787 Proteasome subunit alpha type-2 chr7 Not Cancer Driver No 1 hippie, biogrid 0 0 0 0 0
ERCC6-201 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 142 837 82 82 9
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
ETHE1-201 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 18 6 0 0 8
EZR-202 EZR P15311 Ezrin chr6 Census Yes 1 hippie, biogrid 51 296 26 26 0
FDPS-202 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 1 hippie, biogrid 50 0 0 0 1
FXN-203 FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 17 75 1 1 8
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 55 352 38 38 0
GCSH-201 GCSH P23434 Glycine cleavage system H protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 6 26 0 0 0
GLRX5-201 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 5 23 0 0 2
GRHPR-201 GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 29 36 3 3 0
GSTP1-202 GSTP1 P09211 Glutathione S-transferase P chr11 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
GUK1-209 GUK1 Q16774 Guanylate kinase chr1 Not Cancer Driver No 1 hippie, biogrid 17 73 6 6 0
HADH-201 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 24 22 4 4 3
HDHD3-202 HDHD3 Q9BSH5 Haloacid dehalogenase-like hydrolase domain-containing protein 3 chr9 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 0
HIBCH-201 HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 31 26 0 0 1
HINT1-201 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 1 hippie, biogrid 7 6 0 0 7
HINT2-201 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 6 29 1 1 0
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie, biogrid 33 290 22 22 4
HNRNPH2-201 HNRNPH2 P55795 Heterogeneous nuclear ribonucleoprotein H2 chrX Not Cancer Driver No 1 hippie, biogrid 47 168 21 21 2
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 70 255 29 29 0
ICAM1-201 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 52 253 25 25 0
IDH2-201 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 51 61 0 0 4
LACTB2-201 LACTB2 Q53H82 Endoribonuclease LACTB2 chr8 Not Cancer Driver No 1 hippie, biogrid 26 21 0 0 0
LAP3-201 LAP3 P28838 Cytosol aminopeptidase chr4 Not Cancer Driver No 1 hippie, biogrid 39 100 8 8 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 402 91 13 13 20
LSM3-201 LSM3 P62310 U6 snRNA-associated Sm-like protein LSm3 chr3 Not Cancer Driver No 1 hippie, biogrid 8 28 2 2 0
MAIP1-202 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 23 12 0 0 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 intact, hippie 100 750 99 99 17
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 104 593 69 69 0
MPST-201 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 18 72 9 9 0
MTPN-201 MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 7 11 3 3 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NDRG1-201 NDRG1 Q92597 Protein NDRG1 chr8 Census Yes 1 hippie, biogrid 44 141 18 18 0
NDUFAB1-201 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
NENF-201 NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 12 98 6 6 0
NOS2-201 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie, biogrid 147 201 26 26 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie, biogrid 41 80 13 13 1
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 hippie, biogrid 8 30 0 0 6
PDCD6-201 PDCD6 O75340 Programmed cell death protein 6 chr5 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
PDP1-201 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 51 96 7 7 0
PGLS-201 PGLS O95336 6-phosphogluconolactonase chr19 Not Cancer Driver No 1 hippie, biogrid 18 36 4 4 0
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 48 23 3 3 4
PRDX2-201 PRDX2 P32119 Peroxiredoxin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 22 30 3 3 0
PRDX6-201 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 32 13 3 3 0
PRNP-201 PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 28 117 8 8 19
PSMA1-201 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie, biogrid 33 51 7 7 0
PSMA2-201 PSMA2 P25787 Proteasome subunit alpha type-2 chr7 Not Cancer Driver No 1 hippie, biogrid 14 0 0 0 0
PSMA3-201 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie, biogrid 15 30 1 1 0
PSMA5-201 PSMA5 P28066 Proteasome subunit alpha type-5 chr1 Not Cancer Driver No 1 hippie, biogrid 18 23 1 1 0
PSMB1-201 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie, biogrid 20 15 2 2 0
PSMB4-201 PSMB4 P28070 Proteasome subunit beta type-4 chr1 Not Cancer Driver No 1 hippie, biogrid 19 18 2 2 0
PSMB7-201 PSMB7 Q99436 Proteasome subunit beta type-7 chr9 Not Cancer Driver No 1 hippie, biogrid 19 26 3 3 0
RABIF-201 RABIF P47224 Guanine nucleotide exchange factor MSS4 chr1 Not Cancer Driver No 1 hippie, biogrid 11 25 3 3 0
REL-201 REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 53 365 35 35 0
SEPHS1-201 SEPHS1 P49903 Selenide, water dikinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 43 29 6 6 0
SHC1-202 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 400 41 41 0
SOD1-201 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 14 94 9 9 57
SPR-201 SPR P35270 Sepiapterin reductase chr2 Not Cancer Driver No 1 hippie, biogrid 17 19 4 4 2
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 53 254 26 26 1
ST13-201 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 hippie, biogrid 27 298 21 21 0
SUGT1-202 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 Not Cancer Driver No 1 hippie, biogrid 21 119 0 0 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
TAGLN2-203 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 18 83 8 8 0
TAGLN3-205 TAGLN3 Q9UI15 Transgelin-3 chr3 Not Cancer Driver No 1 hippie, biogrid 19 86 12 12 0
TBCA-202 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 7 30 2 2 0
TPD52-202 TPD52 P55327 Tumor protein D52 chr8 Not Cancer Driver No 1 hippie, biogrid 18 176 14 14 0
TPI1-202 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 hippie, biogrid 27 15 0 0 7
TPRN-202 TPRN Q4KMQ1 Taperin chr9 Not Cancer Driver No 4 intact, hippie, biogrid 34 670 30 30 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
UBA2-201 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 62 221 22 22 4
UCHL1-201 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie, biogrid 23 34 5 5 4
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 24 41 1 1 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 19 81 7 7 0