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CLSPN-202 ,CLSPN ,Q9HAW4
  • Number of Interaction partner in intact: 8
  • Number of Interaction partner in biogrid: 16
  • Number of Interaction partner in hippie: 53
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ASF1A-201 ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 11 69 2 2 0
ATR-201 ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 hippie 261 107 11 11 1
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 57 45 3 3 0
CASP7-203 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 28 75 7 7 0
CBX3-202 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 18 119 13 13 0
CDC20-201 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 36 198 12 12 0
CDC45-201 CDC45 O75419 Cell division control protein 45 homolog chr22 Not Cancer Driver No 2 intact, hippie, biogrid 49 66 12 12 5
CDC7-201 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 1 hippie 49 187 17 17 0
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 intact, hippie 40 34 2 2 0
CEP250-202 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 192 1863 148 148 0
CHEK1-204 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 Not Cancer Driver No 2 intact, hippie 42 86 13 13 0
DHX40-201 DHX40 Q8IX18 Probable ATP-dependent RNA helicase DHX40 chr17 Not Cancer Driver No 1 hippie, biogrid 64 167 17 17 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
FBXO38-202 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 94 441 33 33 1
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 41 20 2 2 6
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GINS3-201 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 25 14 1 1 0
GJB2-202 GJB2 P29033 Gap junction beta-2 protein chr13 Not Cancer Driver No 1 intact, hippie 25 0 0 0 41
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 34 148 6 6 0
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 517 971 113 113 1
HUS1-201 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 biogrid 19 17 1 1 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 143 265 30 30 6
INSR-201 INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 biogrid 139 282 37 37 63
JAK2-201 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 biogrid 81 59 4 4 4
LACC1-201 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 Not Cancer Driver No 1 intact, hippie 40 4 0 0 1
LTA-213 LTA P01374 Lymphotoxin-alpha chr6 Not Cancer Driver No 1 hippie 32 20 4 4 0
LTN1-201 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 Not Cancer Driver No 1 intact, hippie 139 125 15 15 0
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 biogrid 52 2 0 0 6
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 biogrid 32 49 3 3 0
MCM2-201 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie, biogrid 77 277 33 33 1
MPP1-202 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX Not Cancer Driver No 1 hippie 58 194 29 29 0
MSH6-201 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 Census Yes 1 hippie 92 389 26 26 6
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYH7-201 MYH7 P12883 Myosin-7 chr14 Not Cancer Driver No 1 hippie 376 1108 228 228 168
NUP50-201 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 hippie, biogrid 43 335 30 30 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
PARP1-203 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 88 322 28 28 0
PCNA-201 PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 19 22 2 2 1
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 68 120 14 14 0
PMS2-201 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 Census, Compendium Yes 1 hippie 85 336 30 30 8
PRIMPOL-201 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 Not Cancer Driver No 1 intact, hippie 25 92 0 0 1
RAD17-208 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 Census Yes 1 hippie 53 207 12 12 0
RAD9A-201 RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 Not Cancer Driver No 1 hippie 32 136 7 7 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 45 98 7 7 1
RPA2-203 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 20 117 12 12 0
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 10 4 1 1 0
SMG7-201 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 95 664 67 67 0
SP110-203 SP110 Q9HB58 Sp110 nuclear body protein chr2 Not Cancer Driver No 1 hippie 49 374 28 28 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
TERF2IP-201 TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 20 312 12 12 0
TIMELESS-203 TIMELESS Q9UNS1 Protein timeless homolog chr12 Not Cancer Driver No 1 hippie 127 371 44 44 0
TNNC2-201 TNNC2 P02585 Troponin C, skeletal muscle chr20 Not Cancer Driver No 1 hippie, biogrid 21 88 10 10 2
USP20-203 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie 87 296 30 30 0
USP28-201 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 Not Cancer Driver No 1 hippie 106 311 18 18 0
USP29-201 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 Not Cancer Driver No 1 hippie 236 433 114 114 0
USP7-201 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 hippie 135 215 34 34 7
UTP4-201 UTP4 Q969X6 U3 small nucleolar RNA-associated protein 4 homolog chr16 Not Cancer Driver No 1 hippie 43 34 4 4 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0